iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088307

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03176416

Gene Name

FBXL5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000007026.2	ENSOGAT00000007030.2	ENSOGAP00000006290.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	9.10e-06	25.8	179	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 100  aglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
           ++ +++lp e++++i+++l+++el+r+++v+ +w++la++ +lwk++
   Q: 179  STGITHLPPEVMLSIFSYLNPQELCRCSQVSTKWSQLAKTGSLWKHL 225
           556789*********************************9****987 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

LLCVKLSKTN FSNNNDFRAL LQSLYATFKE FKMHEQIENE YIIGLLQQRS QTIYNVHSDN 60
KLSEMLSLFE KGLKNVKNEY EQLNYAKQLK ERLEAFTRDF LPHMKEEEEV FQPMLMEYFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCTGTGTG TAAAAGTAAA TAGGGAAGTA TTTGAATATT TCTCATTGTT GGATATTTGC 60
ATGTATTGAT TATGCCTTTC TTTTTAAATT TTTATTCAGC TTTCTAAAAC GAATTTTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005506--F:iron ion binding
GO:0055072--P:iron ion homeostasis
GO:1903364--P:positive regulation of cellular protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002319	Ailuropoda melanoleuca	95.06	0.00e+00	1205.00
IUUC-Apl-003755	Anas platyrhynchos	80.12	0.00e+00	1014.00
IUUC-Aca-004798	Anolis carolinensis	76.72	0.00e+00	1003.00
IUUC-Ame-011091	Astyanax mexicanus	58.08	0.00e+00	721.00
IUUC-Bta-013204	Bos taurus	93.41	0.00e+00	1213.00
IUUC-Cja-019594	Callithrix jacchus	94.69	0.00e+00	1048.00
IUUC-Cfa-020965	Canis familiaris	95.33	0.00e+00	1195.00
IUUC-Cpo-021308	Cavia porcellus	91.92	0.00e+00	1186.00
IUUC-Csa-023865	Chlorocebus sabaeus	95.06	0.00e+00	1258.00
IUUC-Cho-024778	Choloepus hoffmanni	83.24	4.00e-165	574.00
IUUC-Dre-027628	Danio rerio	53.46	2.00e-160	559.00
IUUC-Dno-029899	Dasypus novemcinctus	92.51	0.00e+00	1238.00
IUUC-Dor-031105	Dipodomys ordii	79.97	0.00e+00	1003.00
IUUC-Ete-032314	Echinops telfairi	86.58	0.00e+00	1085.00
IUUC-Eca-033797	Equus caballus	94.03	0.00e+00	1145.00
IUUC-Eeu-034811	Erinaceus europaeus	85.56	0.00e+00	904.00
IUUC-Fca-036516	Felis catus	94.73	0.00e+00	1186.00
IUUC-Fal-036824	Ficedula albicollis	78.18	0.00e+00	946.00
IUUC-Gga-040271	Gallus gallus	79.82	0.00e+00	1019.00
IUUC-Gac-041399	Gasterosteus aculeatus	61.97	0.00e+00	755.00
IUUC-Ggo-044415	Gorilla gorilla	95.21	0.00e+00	1258.00
IUUC-Hsa-047001	Homo sapiens	95.36	0.00e+00	1283.00
IUUC-Itr-048356	Ictidomys tridecemlineatus	93.07	0.00e+00	1054.00
IUUC-Lch-049897	Latimeria chalumnae	64.84	0.00e+00	788.00
IUUC-Loc-052162	Lepisosteus oculatus	65.13	0.00e+00	815.00
IUUC-Laf-054031	Loxodonta africana	94.61	0.00e+00	1215.00
IUUC-Mcc-054680	Macaca mulatta	95.06	0.00e+00	1258.00
IUUC-Meu-056199	Macropus eugenii	81.55	1.00e-105	377.00
IUUC-Mga-059675	Meleagris gallopavo	80.36	0.00e+00	1029.00
IUUC-Mmr-061694	Microcebus murinus	95.51	0.00e+00	1265.00
IUUC-Mdo-062900	Monodelphis domestica	88.92	0.00e+00	1165.00
IUUC-Mmu-063178	Mus musculus	92.64	0.00e+00	1209.00
IUUC-Mpu-066584	Mustela putorius furo	94.16	0.00e+00	1199.00
IUUC-Mlu-067859	Myotis lucifugus	93.67	0.00e+00	1196.00
IUUC-Nle-069172	Nomascus leucogenys	95.81	0.00e+00	1236.00
IUUC-Opr-070992	Ochotona princeps	90.63	0.00e+00	1022.00
IUUC-Ont-072577	Oreochromis niloticus	60.72	0.00e+00	754.00
IUUC-Oan-072870	Ornithorhynchus anatinus	84.34	0.00e+00	909.00
IUUC-Ocu-074849	Oryctolagus cuniculus	93.54	0.00e+00	1226.00
IUUC-Ola-087146	Oryzias latipes	59.45	0.00e+00	739.00
IUUC-Oar-090192	Ovis aries	93.98	0.00e+00	1211.00
IUUC-Ptr-091049	Pan troglodytes	95.51	0.00e+00	1263.00
IUUC-Pan-091995	Papio anubis	95.21	0.00e+00	1260.00
IUUC-Psi-093154	Pelodiscus sinensis	80.06	0.00e+00	1003.00
IUUC-Pma-094334	Petromyzon marinus	46.86	3.00e-142	498.00
IUUC-Pfo-096154	Poecilia formosa	59.16	0.00e+00	723.00
IUUC-Pab-098264	Pongo abelii	95.78	0.00e+00	1261.00
IUUC-Pca-100884	Procavia capensis	71.71	0.00e+00	889.00
IUUC-Pva-102114	Pteropus vampyrus	93.72	0.00e+00	1229.00
IUUC-Rno-105392	Rattus norvegicus	93.69	0.00e+00	1218.00
IUUC-Sha-106508	Sarcophilus harrisii	89.02	0.00e+00	1165.00
IUUC-Sar-113107	Sorex araneus	91.12	0.00e+00	855.00
IUUC-Ssc-115489	Sus scrofa	94.61	0.00e+00	1191.00
IUUC-Tgu-116734	Taeniopygia guttata	78.48	0.00e+00	994.00
IUUC-Tru-117632	Takifugu rubripes	59.85	0.00e+00	740.00
IUUC-Tsy-119400	Tarsius syrichta	94.42	0.00e+00	1224.00
IUUC-Tni-120602	Tetraodon nigroviridis	58.58	0.00e+00	754.00
IUUC-Tbe-127833	Tupaia belangeri	91.57	0.00e+00	642.00
IUUC-Ttr-129289	Tursiops truncatus	92.87	0.00e+00	750.00
IUUC-Vpa-130253	Vicugna pacos	95.86	0.00e+00	642.00
IUUC-Vvi-131468	Vitis vinifera	32.39	2.00e-05	43.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence