iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048657

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01046192

Gene Name

UBA7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000013749.2	ENSSTOT00000013757.2	ENSSTOP00000012328.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	5.30e-193	641.8	402	880

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkel 84
           YD+Qi+++G+  q+kl+ ++++lvG g++GcEllK ++l+G+     g +t+ Dmd+ve snl+rqFLfr +dvg++KAevaaea+++l
   Q: 402  YDGQIAVFGAGFQKKLSLQHYFLVGTGAIGCELLKDFALVGLgaggcGGVTIADMDHVEHSNLSRQFLFRTHDVGRPKAEVAAEAAQKL 490
           ***************************************************************************************** PP
   S: 85   npdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd...dpp 167
           npd +v++   s+++++e+i+   Ff+++d+Vv+ald++ ar +v+ +c+++ +pl+e+gt G++G ++v+i+++te ys +     ++
   Q: 491  NPDLRVTPLIRSLDPTTEHIFgdnFFSNVDGVVAALDSFPARHYVAARCTHYLKPLLEAGTQGTWGSASVFIPHVTEVYSGPVsasASE 579
           **********************************************************************************9999999 PP
   S: 168  qktiPfctlketpnaaehtiewa............vlfnklleeeag.e...eevlekldseekeegkdkvkselksedeenfeeaiei 240
           +   P+ct + +p++aeh+++wa              +n+++ ++++      + l+++d++++++ +   + ++ +++++++++++ +
   Q: 580  DAPHPVCTGRYFPSTAEHSLQWArnefealfqlsaKTINQTQLQTSFfLhraRTSLADMDRQQILTLL---RLGVLGQRPQTWQNCVVW 665
           9999***************************6666444444333332121113444444444444444...445888************ PP
   S: 241  avkafakttinsikqllksfecdivtkskspfwv...............................................sfcsnaea 282
           a+ +++ +++++i+qllk+f++d+v k+++pfw+                                                       
   Q: 666  ALGQWQFCFHYGITQLLKHFPPDKVLKDGTPFWSspkqcpqplefdanqdmhllyvlaaanlyaqmhgipgssdqtalrelL------- 747
           **********************************999999999777777777777777777777777666665555544331....... PP
   S: 283  lqvp.............ekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds.avdlvtaaanlraeslgiepk 352
              +              ++++ +++++   +     l+ l +ale + k + +kp  l+fekdd   ++d+vtaaa+lr +++gi + 
   Q: 748  ---KlpqpdpqhlslifTNNLELTWASA---EfgpemLKKLQEALEVWGKFPPLKP--LMFEKDDSNfHMDFVTAAASLRSQNYGIIS- 827
           ...0333333334433344444444333...24558899999*************9..******************************. PP
   S: 353  ldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfda 403
           +++++ k+i+g+iipaiatt+a+v+Gl+ +E++Kvv g    +++++ +l++a
   Q: 828  VNYSQSKRIMGQIIPAIATTTAAVAGLVGLELYKVVYGarSLSAFRHSYLHLA 880
           ************************************99777778888888776 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSLDEEIYSR QLYVLGPLAM QRIQKAKVLL SGLKGLGAEV AKNLVLMGIG SLTLHDPHPT 60
CWSDLAAQVF LSENDLEKNR ADASQKHLAQ LNEAVQVFVH TGDITEDLLL NFQVVVLTAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGCTGG ATGAGGAGAT ATACTCCCGG CAGCTGTGAG CCTTGAGGTG GATAGGGAGT 60
GGGGTGGCCT TCAGACCTCT CTGATCTCTA GATGCCTGTC CTCCTACTTC CCATCCACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0019782--F:ISG15 activating enzyme activity
GO:0032020--P:ISG15-protein conjugation
GO:0019941--P:modification-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001816	Ailuropoda melanoleuca	73.72	0.00e+00	1375.00
IUUC-Bta-012665	Bos taurus	71.95	0.00e+00	1265.00
IUUC-Cja-019047	Callithrix jacchus	75.07	0.00e+00	1403.00
IUUC-Cfa-021225	Canis familiaris	76.56	0.00e+00	1450.00
IUUC-Cpo-022336	Cavia porcellus	70.19	0.00e+00	1302.00
IUUC-Csa-023462	Chlorocebus sabaeus	78.83	0.00e+00	1400.00
IUUC-Cho-024436	Choloepus hoffmanni	71.31	2.00e-93	337.00
IUUC-Dno-029347	Dasypus novemcinctus	73.91	0.00e+00	1368.00
IUUC-Dor-030997	Dipodomys ordii	72.69	0.00e+00	1360.00
IUUC-Ete-033124	Echinops telfairi	70.99	0.00e+00	937.00
IUUC-Eca-033929	Equus caballus	76.68	0.00e+00	1475.00
IUUC-Eeu-034717	Erinaceus europaeus	65.95	0.00e+00	925.00
IUUC-Fca-036564	Felis catus	76.21	0.00e+00	1420.00
IUUC-Ggo-044480	Gorilla gorilla	78.49	0.00e+00	1398.00
IUUC-Hsa-046498	Homo sapiens	77.65	0.00e+00	1380.00
IUUC-Laf-054119	Loxodonta africana	73.39	0.00e+00	1392.00
IUUC-Mcc-055597	Macaca mulatta	76.70	0.00e+00	1324.00
IUUC-Meu-056534	Macropus eugenii	47.81	0.00e+00	845.00
IUUC-Mdo-063058	Monodelphis domestica	56.06	0.00e+00	993.00
IUUC-Mmu-063578	Mus musculus	71.47	0.00e+00	1361.00
IUUC-Mpu-066255	Mustela putorius furo	75.62	0.00e+00	1420.00
IUUC-Mlu-067814	Myotis lucifugus	71.41	0.00e+00	1263.00
IUUC-Nle-069193	Nomascus leucogenys	78.25	0.00e+00	1399.00
IUUC-Opr-070715	Ochotona princeps	70.23	0.00e+00	1294.00
IUUC-Ocu-074162	Oryctolagus cuniculus	73.42	0.00e+00	1362.00
IUUC-Oga-088895	Otolemur garnettii	76.31	0.00e+00	1390.00
IUUC-Oar-089579	Ovis aries	71.49	0.00e+00	1261.00
IUUC-Ptr-090581	Pan troglodytes	77.52	0.00e+00	1358.00
IUUC-Pan-092458	Papio anubis	78.54	0.00e+00	1382.00
IUUC-Pab-098653	Pongo abelii	73.29	0.00e+00	1305.00
IUUC-Pca-100578	Procavia capensis	70.17	0.00e+00	800.00
IUUC-Pva-102914	Pteropus vampyrus	74.17	0.00e+00	1128.00
IUUC-Rno-106066	Rattus norvegicus	71.91	0.00e+00	1377.00
IUUC-Sha-107368	Sarcophilus harrisii	57.09	0.00e+00	1067.00
IUUC-Ssc-115743	Sus scrofa	76.06	0.00e+00	1416.00
IUUC-Tbe-127587	Tupaia belangeri	77.23	0.00e+00	1074.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence