iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090050

Ensembl Protein ID

ENSOARP00000014245.1

UniProt Accession

W5PUW3; W5PUW3_SHEEP

Genbank Protein ID

ENSOARP00000014245

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01036095

Gene Name

TRIO

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000013279.1	ENSOART00000014452.1	ENSOARP00000014245.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-12	47.7	1649	1700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk..elegkrGlfP 55
             v++d++a n+ eLt+++G +v+v+e  +   +W+           +Gl+P
   Q: 1649 TVVIHDFTACNSTELTIRRGQTVEVLERPHDKPDWCLVRTtdRSPAAEGLVP 1700
           679********************************97755334445678887 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MGVKKAAVLA LEIRVVQKLN DTQATQSLYF LLCLSGFRKN DEMKAMDVLP ILKEKVAYLS 60
GGRDKRGGPI LTFPARSNHD RIRQEDLRRL ISYLACIPSE EVCKRGFTVI VDMRGSKWDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTGTAA AGAAAGCAGC TGTGTTGGCA TTGGAGATAA GGGTGGTTCA GAAATTAAAT 60
GACACTCAAG CAACCCAGTC ATTATATTTT CTCCTTTGTC TTTCAGGGTT TCGAAAAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR001251--CRAL-TRIO_dom
IPR000219--DH-domain
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR013098--Ig_I-set
IPR003598--Ig_sub2
IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain
IPR018159--Spectrin/alpha-actinin
IPR002017--Spectrin_repeat
IPR028570--TRIO

PROSITE

PS50191--CRAL_TRIO
PS50010--DH_2
PS50835--IG_LIKE
PS50003--PH_DOMAIN
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF00650--CRAL_TRIO
PF07679--I-set
PF00169--PH
PF00069--Pkinase
PF00621--RhoGEF
PF00018--SH3_1
PF00435--Spectrin

SMART

SM00408--IGc2
SM00233--PH
SM00325--RhoGEF
SM00220--S_TKc
SM00516--SEC14
SM00326--SH3
SM00150--SPEC

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001797	Ailuropoda melanoleuca	96.03	0.00e+00	4271.00
IUUC-Apl-003498	Anas platyrhynchos	94.28	0.00e+00	4185.00
IUUC-Bta-013121	Bos taurus	95.68	0.00e+00	4233.00
IUUC-Cja-018919	Callithrix jacchus	95.72	0.00e+00	4264.00
IUUC-Cfa-020547	Canis familiaris	95.79	0.00e+00	4244.00
IUUC-Cpo-022301	Cavia porcellus	95.63	0.00e+00	4263.00
IUUC-Csa-023889	Chlorocebus sabaeus	95.76	0.00e+00	4263.00
IUUC-Dre-028386	Danio rerio	85.71	0.00e+00	3783.00
IUUC-Dno-028888	Dasypus novemcinctus	95.39	0.00e+00	4222.00
IUUC-Dor-030992	Dipodomys ordii	88.76	0.00e+00	3879.00
IUUC-Ete-033167	Echinops telfairi	89.29	0.00e+00	1653.00
IUUC-Eca-033685	Equus caballus	96.05	0.00e+00	4238.00
IUUC-Fca-035647	Felis catus	95.62	0.00e+00	4264.00
IUUC-Fal-036845	Ficedula albicollis	94.30	0.00e+00	4218.00
IUUC-Gga-040959	Gallus gallus	94.69	0.00e+00	4231.00
IUUC-Gac-041349	Gasterosteus aculeatus	84.26	0.00e+00	3653.00
IUUC-Ggo-045170	Gorilla gorilla	96.01	0.00e+00	4256.00
IUUC-Hsa-046059	Homo sapiens	95.72	0.00e+00	4267.00
IUUC-Lch-050010	Latimeria chalumnae	89.50	0.00e+00	3940.00
IUUC-Loc-052783	Lepisosteus oculatus	89.14	0.00e+00	3981.00
IUUC-Laf-053884	Loxodonta africana	95.52	0.00e+00	4240.00
IUUC-Mcc-055804	Macaca mulatta	95.13	0.00e+00	4252.00
IUUC-Mga-060008	Meleagris gallopavo	94.43	0.00e+00	4212.00
IUUC-Mmr-061081	Microcebus murinus	95.60	0.00e+00	4266.00
IUUC-Mdo-062888	Monodelphis domestica	94.90	0.00e+00	3893.00
IUUC-Mmu-063327	Mus musculus	95.27	0.00e+00	4220.00
IUUC-Mpu-066905	Mustela putorius furo	95.77	0.00e+00	4275.00
IUUC-Mlu-068215	Myotis lucifugus	92.78	0.00e+00	4169.00
IUUC-Nle-069414	Nomascus leucogenys	93.26	0.00e+00	4117.00
IUUC-Opr-070819	Ochotona princeps	92.19	0.00e+00	4076.00
IUUC-Ont-072678	Oreochromis niloticus	85.71	0.00e+00	3754.00
IUUC-Oan-072974	Ornithorhynchus anatinus	94.88	0.00e+00	4236.00
IUUC-Ocu-074919	Oryctolagus cuniculus	95.67	0.00e+00	4253.00
IUUC-Oga-088068	Otolemur garnettii	95.43	0.00e+00	4268.00
IUUC-Ptr-090841	Pan troglodytes	95.76	0.00e+00	4262.00
IUUC-Psi-093088	Pelodiscus sinensis	94.89	0.00e+00	4192.00
IUUC-Pfo-097201	Poecilia formosa	85.81	0.00e+00	2495.00
IUUC-Pab-098130	Pongo abelii	95.67	0.00e+00	4254.00
IUUC-Pca-100839	Procavia capensis	92.65	0.00e+00	2528.00
IUUC-Pva-102115	Pteropus vampyrus	96.76	0.00e+00	2654.00
IUUC-Rno-105207	Rattus norvegicus	95.28	0.00e+00	4214.00
IUUC-Sha-107011	Sarcophilus harrisii	88.96	0.00e+00	2925.00
IUUC-Tgu-116970	Taeniopygia guttata	94.14	0.00e+00	4157.00
IUUC-Tru-117758	Takifugu rubripes	84.52	0.00e+00	3719.00
IUUC-Ttr-128857	Tursiops truncatus	88.76	0.00e+00	2579.00
IUUC-Xtr-131909	Xenopus tropicalis	89.79	0.00e+00	3981.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence