iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097907

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01350403

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000005050.2	ENSPPYT00000005974.2	ENSPPYP00000005754.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-14	54.4	660	725

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede.....k.....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++     +     +l+eC++C+e++Hp+Clk++     v++elpn+  w+CpkC+++
   Q: 660  AVCLVCGEAGKEDtveeeEgkfnlMLMECSICNEIIHPGCLKIKesegvVNDELPNC--WECPKCNHA 725
           79*********9977765156789*********************************..*******85 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAGPQMGGYA EDHPPRKRHA AEKQKKKTVI YTKCFEFESA IQRPIDRQRY DENEDLSDVE 60
EIVSVRGFSL EEKLRSQLYQ GDFVHAMEGK DFNYEYVQRE ALRVPLIFRE KDGLGIKMPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGGTC CGCAAATGGG GGGATATGCA GAGGATCACC CCCCACGAAA AAGACATGCA 60
GCAGAAAAGC AAAAAAAAGA AAACAGTTAT ATATACAAAA TGCTTTGAAT TTGAGTCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0048596--P:embryonic camera-type eye morphogenesis
GO:0021592--P:fourth ventricle development
GO:0035518--P:histone H2A monoubiquitination
GO:0070544--P:histone H3-K36 demethylation
GO:0021993--P:initiation of neural tube closure
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0021555--P:midbrain-hindbrain boundary morphogenesis
GO:2000178--P:negative regulation of neural precursor cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030307--P:positive regulation of cell growth
GO:1902459--P:positive regulation of stem cell population maintenance
GO:0007283--P:spermatogenesis
GO:0021678--P:third ventricle development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	91.56	0.00e+00	2122.00
IUUC-Apl-003787	Anas platyrhynchos	79.60	0.00e+00	1776.00
IUUC-Aca-004247	Anolis carolinensis	74.48	0.00e+00	1661.00
IUUC-Ago-007912	Ashbya gossypii	40.86	2.00e-48	186.00
IUUC-Acl-008303	Aspergillus clavatus	45.25	1.00e-63	239.00
IUUC-Afl-008579	Aspergillus flavus	42.55	2.00e-23	104.00
IUUC-Afu-008903	Aspergillus fumigatus	43.71	5.00e-64	239.00
IUUC-Ani-009279	Aspergillus nidulans	46.83	2.00e-63	238.00
IUUC-Ang-009645	Aspergillus niger	45.08	1.00e-60	228.00
IUUC-Aor-010233	Aspergillus oryzae	46.01	2.00e-63	238.00
IUUC-Ate-010345	Aspergillus terreus	46.01	4.00e-65	243.00
IUUC-Ame-011463	Astyanax mexicanus	75.00	4.00e-168	585.00
IUUC-Bta-013531	Bos taurus	91.76	0.00e+00	2154.00
IUUC-Cel-018303	Caenorhabditis elegans	44.55	2.00e-82	300.00
IUUC-Cja-018876	Callithrix jacchus	88.25	0.00e+00	2090.00
IUUC-Cfa-020857	Canis familiaris	92.30	0.00e+00	2165.00
IUUC-Cpo-021967	Cavia porcellus	88.43	0.00e+00	1962.00
IUUC-Csa-023210	Chlorocebus sabaeus	94.53	0.00e+00	2139.00
IUUC-Cin-025140	Ciona intestinalis	60.43	1.00e-105	377.00
IUUC-Csv-025861	Ciona savignyi	56.79	4.00e-115	409.00
IUUC-Cne-026797	Cryptococcus neoformans	38.55	3.00e-57	216.00
IUUC-Cme-027118	Cyanidioschyzon merolae	36.00	1.00e-48	187.00
IUUC-Dre-028272	Danio rerio	60.20	0.00e+00	1378.00
IUUC-Dno-030034	Dasypus novemcinctus	89.98	0.00e+00	2073.00
IUUC-Dor-030736	Dipodomys ordii	77.91	0.00e+00	837.00
IUUC-Dse-031402	Dothistroma septosporum	42.81	3.00e-60	228.00
IUUC-Dme-032039	Drosophila melanogaster	59.51	2.00e-120	427.00
IUUC-Eca-034255	Equus caballus	92.46	0.00e+00	2078.00
IUUC-Eeu-035038	Erinaceus europaeus	88.87	0.00e+00	1030.00
IUUC-Fca-035786	Felis catus	91.63	0.00e+00	2128.00
IUUC-Fal-037589	Ficedula albicollis	79.27	0.00e+00	1883.00
IUUC-Gmo-038781	Gadus morhua	63.47	0.00e+00	689.00
IUUC-Gga-041103	Gallus gallus	86.47	0.00e+00	1148.00
IUUC-Gac-041304	Gasterosteus aculeatus	57.35	0.00e+00	1360.00
IUUC-Ggo-044522	Gorilla gorilla	93.85	0.00e+00	1608.00
IUUC-Hsa-045877	Homo sapiens	94.99	0.00e+00	2247.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	89.13	0.00e+00	1165.00
IUUC-Kpa-049384	Komagataella pastoris	39.67	1.00e-53	204.00
IUUC-Lch-049950	Latimeria chalumnae	73.42	0.00e+00	1746.00
IUUC-Loc-051972	Lepisosteus oculatus	71.91	0.00e+00	1093.00
IUUC-Lma-053190	Leptosphaeria maculans	43.35	2.00e-59	224.00
IUUC-Laf-053623	Loxodonta africana	91.73	0.00e+00	2041.00
IUUC-Mcc-054943	Macaca mulatta	94.54	0.00e+00	2239.00
IUUC-Meu-056259	Macropus eugenii	81.76	0.00e+00	1926.00
IUUC-Mla-058890	Melampsora laricipopulina	49.22	1.00e-70	259.00
IUUC-Mga-059671	Meleagris gallopavo	80.06	0.00e+00	1835.00
IUUC-Mvi-060481	Microbotryum violaceum	43.70	5.00e-65	243.00
IUUC-Mmr-061003	Microcebus murinus	91.67	0.00e+00	2135.00
IUUC-Mmu-063584	Mus musculus	90.06	0.00e+00	2077.00
IUUC-Mpu-066056	Mustela putorius furo	92.07	0.00e+00	2130.00
IUUC-Mlu-067850	Myotis lucifugus	91.22	0.00e+00	2118.00
IUUC-Nfi-068537	Neosartorya fischeri	45.25	1.00e-63	239.00
IUUC-Nle-069837	Nomascus leucogenys	91.48	0.00e+00	1921.00
IUUC-Opr-070943	Ochotona princeps	87.05	0.00e+00	2005.00
IUUC-Ont-071663	Oreochromis niloticus	61.22	0.00e+00	1446.00
IUUC-Oan-072934	Ornithorhynchus anatinus	69.83	0.00e+00	1102.00
IUUC-Ocu-074706	Oryctolagus cuniculus	91.67	0.00e+00	2145.00
IUUC-Ola-086543	Oryzias latipes	59.76	0.00e+00	1412.00
IUUC-Oga-088671	Otolemur garnettii	84.07	0.00e+00	1006.00
IUUC-Oar-089560	Ovis aries	86.92	0.00e+00	2055.00
IUUC-Ptr-090875	Pan troglodytes	94.99	0.00e+00	2280.00
IUUC-Pan-091788	Papio anubis	90.96	0.00e+00	2161.00
IUUC-Psi-093382	Pelodiscus sinensis	79.68	0.00e+00	1878.00
IUUC-Pno-094984	Phaeosphaeria nodorum	44.87	6.00e-61	229.00
IUUC-Ppa-095609	Physcomitrella patens	42.06	6.00e-56	210.00
IUUC-Pfo-096272	Poecilia formosa	58.53	0.00e+00	1307.00
IUUC-Pca-100628	Procavia capensis	81.25	0.00e+00	1714.00
IUUC-Pva-102956	Pteropus vampyrus	95.09	0.00e+00	1187.00
IUUC-Pgr-103554	Puccinia graminis	45.55	2.00e-72	266.00
IUUC-Ptt-103859	Puccinia triticina	44.29	1.00e-72	268.00
IUUC-Pte-104241	Pyrenophora teres	41.84	2.00e-59	224.00
IUUC-Pyt-104741	Pyrenophora triticirepentis	41.84	9.00e-59	222.00
IUUC-Rno-105722	Rattus norvegicus	89.70	0.00e+00	1661.00
IUUC-Sce-106445	Saccharomyces cerevisiae	44.30	8.00e-49	187.00
IUUC-Sha-106626	Sarcophilus harrisii	76.53	0.00e+00	1691.00
IUUC-Sja-107763	Schizosaccharomyces japonicus	31.44	2.00e-41	164.00
IUUC-Spo-108120	Schizosaccharomyces pombe	30.79	6.00e-48	186.00
IUUC-Smo-109024	Selaginella moellendorffii	39.10	1.00e-55	211.00
IUUC-Sre-115112	Sporisorium reilianum	40.16	1.00e-57	217.00
IUUC-Ssc-115918	Sus scrofa	89.54	0.00e+00	1601.00
IUUC-Tgu-117229	Taeniopygia guttata	74.44	0.00e+00	1112.00
IUUC-Tru-118638	Takifugu rubripes	69.27	0.00e+00	990.00
IUUC-Tni-120020	Tetraodon nigroviridis	50.86	0.00e+00	659.00
IUUC-Tme-127054	Tuber melanosporum	40.15	1.00e-52	202.00
IUUC-Tbe-127654	Tupaia belangeri	74.78	0.00e+00	1510.00
IUUC-Ttr-128821	Tursiops truncatus	84.17	0.00e+00	1944.00
IUUC-Uma-129458	Ustilago maydis	39.15	2.00e-57	217.00
IUUC-Vpa-130655	Vicugna pacos	57.50	0.00e+00	714.00
IUUC-Xtr-131823	Xenopus tropicalis	70.50	0.00e+00	1609.00
IUUC-Xma-133305	Xiphophorus maculatus	60.81	0.00e+00	1385.00
IUUC-Yli-134626	Yarrowia lipolytica	42.71	1.00e-55	211.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence