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Tag Content
iUUCD ID IUUC-Ssc-116344
Ensembl Protein ID ENSSSCP00000009255.2
UniProt Accession F1S8S0; F1S8S0_PIG
Genbank Protein ID ENSSSCP00000009255
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID FP102127
Gene Name WHSC1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000008682.2 ENSSSCT00000009499.2 ENSSSCP00000009255.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.30e-15 57.6 829 869
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 829  WCFVCSKGGS----LLCCESCPAAFHPDCLNIE----MPDGS-WFCNDCR 869
           8*********....*******************....9***8.******8 PP
   
Organism Sus scrofa
Protein Sequence
(Fasta)
ERIQPQQSPL SGPKAVPRAR MKQAPEILGS PNGKAPSCDV SRECSVFLSK AQLSASLQEG 60
VVQKFNGHDA LPFIPAEKLK DLTSRVFNGE PGAHDARLRF ESQEVKGLGT PPHTTPVKNG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ssc-116344|E3,PHD|Sus scrofa
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GATTCCTGTC CTTTTGCCAA TATTAGAGCG GCCTCCTGGA GTTGCCGCTG TGGGTGAAGA 60
ATCCAACGGC AGCAGCTCAG GCTGCTGGAG CGGCGTGGGT TCGGGGCCCG GCCCGCGCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ssc-116344|E3,PHD|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET
SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00184--RING
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0003289--P:atrial septum primum morphogenesis
GO:0003290--P:atrial septum secundum morphogenesis
GO:0060348--P:bone development
GO:0010452--P:histone H3-K36 methylation
GO:0034770--P:histone H4-K20 methylation
GO:0003149--P:membranous septum morphogenesis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:2001032--P:regulation of double-strand break repair via nonhomologous end joining
GO:0070201--P:regulation of establishment of protein localization
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002181 Ailuropoda melanoleuca 86.59 0.00e+00 2317.00
IUUC-Apl-003677 Anas platyrhynchos 75.73 0.00e+00 2017.00
IUUC-Aca-004278 Anolis carolinensis 74.07 0.00e+00 1357.00
IUUC-Ame-011932 Astyanax mexicanus 70.22 0.00e+00 1014.00
IUUC-Bta-012522 Bos taurus 87.01 0.00e+00 2261.00
IUUC-Cja-018908 Callithrix jacchus 85.62 0.00e+00 2235.00
IUUC-Cfa-020894 Canis familiaris 85.91 0.00e+00 2358.00
IUUC-Cpo-021982 Cavia porcellus 83.06 0.00e+00 2214.00
IUUC-Csa-023807 Chlorocebus sabaeus 86.15 0.00e+00 2253.00
IUUC-Cho-024405 Choloepus hoffmanni 68.98 0.00e+00 672.00
IUUC-Dre-027492 Danio rerio 70.77 0.00e+00 1054.00
IUUC-Dno-030020 Dasypus novemcinctus 82.57 0.00e+00 1934.00
IUUC-Dor-031103 Dipodomys ordii 78.21 0.00e+00 2013.00
IUUC-Ete-032488 Echinops telfairi 77.58 0.00e+00 1993.00
IUUC-Eca-034066 Equus caballus 85.84 0.00e+00 2328.00
IUUC-Eeu-035199 Erinaceus europaeus 69.07 0.00e+00 727.00
IUUC-Fca-035434 Felis catus 84.77 0.00e+00 1942.00
IUUC-Fal-037113 Ficedula albicollis 73.79 0.00e+00 2008.00
IUUC-Gmo-039686 Gadus morhua 70.73 0.00e+00 1007.00
IUUC-Gga-040273 Gallus gallus 73.95 0.00e+00 1986.00
IUUC-Gac-042123 Gasterosteus aculeatus 49.89 0.00e+00 1201.00
IUUC-Ggo-044643 Gorilla gorilla 85.82 0.00e+00 2280.00
IUUC-Hsa-046380 Homo sapiens 85.75 0.00e+00 2244.00
IUUC-Itr-048658 Ictidomys tridecemlineatus 89.39 0.00e+00 1401.00
IUUC-Lch-050217 Latimeria chalumnae 65.58 0.00e+00 1673.00
IUUC-Lpe-051201 Leersia perrieri 27.54 2.00e-10 60.80
IUUC-Loc-052766 Lepisosteus oculatus 57.96 0.00e+00 1256.00
IUUC-Laf-053780 Loxodonta africana 83.90 0.00e+00 2279.00
IUUC-Mcc-054928 Macaca mulatta 86.23 0.00e+00 2284.00
IUUC-Mga-059576 Meleagris gallopavo 74.78 0.00e+00 1994.00
IUUC-Mmr-061045 Microcebus murinus 84.23 0.00e+00 2284.00
IUUC-Mdo-062576 Monodelphis domestica 77.41 0.00e+00 2082.00
IUUC-Mmu-063640 Mus musculus 83.50 0.00e+00 2217.00
IUUC-Mac-065303 Musa acuminata 28.66 4.00e-10 59.70
IUUC-Mpu-066512 Mustela putorius furo 86.50 0.00e+00 2300.00
IUUC-Mlu-067280 Myotis lucifugus 78.82 0.00e+00 1078.00
IUUC-Nle-069896 Nomascus leucogenys 85.78 0.00e+00 2162.00
IUUC-Ont-072197 Oreochromis niloticus 71.51 0.00e+00 1015.00
IUUC-Oan-072724 Ornithorhynchus anatinus 76.17 0.00e+00 1306.00
IUUC-Ocu-074758 Oryctolagus cuniculus 82.32 0.00e+00 2164.00
IUUC-Ogl-077641 Oryza glaberrima 28.25 2.00e-10 59.70
IUUC-Oin-079557 Oryza indica 28.90 3.00e-10 59.30
IUUC-Olo-080702 Oryza longistaminata 41.47 2.00e-45 177.00
IUUC-Opu-083371 Oryza punctata 41.88 2.00e-47 184.00
IUUC-Osa-085353 Oryza sativa 28.25 2.00e-10 59.70
IUUC-Oga-088702 Otolemur garnettii 83.97 0.00e+00 1945.00
IUUC-Oar-089736 Ovis aries 80.60 0.00e+00 1916.00
IUUC-Ptr-091055 Pan troglodytes 85.97 0.00e+00 2243.00
IUUC-Pan-092752 Papio anubis 91.98 0.00e+00 1388.00
IUUC-Psi-093620 Pelodiscus sinensis 76.69 0.00e+00 2035.00
IUUC-Pfo-097464 Poecilia formosa 50.45 0.00e+00 1192.00
IUUC-Pab-098051 Pongo abelii 85.67 0.00e+00 2271.00
IUUC-Pop-099927 Populus trichocarpa 28.10 8.00e-12 65.50
IUUC-Pca-100273 Procavia capensis 83.59 0.00e+00 2235.00
IUUC-Ppe-101635 Prunus persica 28.80 2.00e-11 64.30
IUUC-Pva-102473 Pteropus vampyrus 79.32 0.00e+00 1915.00
IUUC-Rno-105056 Rattus norvegicus 83.84 0.00e+00 2235.00
IUUC-Sha-107494 Sarcophilus harrisii 78.05 0.00e+00 2071.00
IUUC-Sar-113310 Sorex araneus 85.59 0.00e+00 1776.00
IUUC-Sbi-114581 Sorghum bicolor 31.48 3.00e-09 55.50
IUUC-Tgu-116786 Taeniopygia guttata 75.89 0.00e+00 2004.00
IUUC-Tru-117638 Takifugu rubripes 50.04 0.00e+00 1221.00
IUUC-Tsy-118937 Tarsius syrichta 89.37 0.00e+00 1474.00
IUUC-Tni-120452 Tetraodon nigroviridis 54.46 0.00e+00 1164.00
IUUC-Tae-125237 Triticum aestivum 28.08 2.00e-06 46.20
IUUC-Tbe-127291 Tupaia belangeri 82.16 0.00e+00 1461.00
IUUC-Ttr-129017 Tursiops truncatus 83.38 0.00e+00 1727.00
IUUC-Xtr-132673 Xenopus tropicalis 66.23 0.00e+00 1726.00
Created Date 25-Jun-2017

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