iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035858

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02049438

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000006160.3	ENSFCAT00000006164.3	ENSFCAP00000005728.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.10e-220	732.0	420	907

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G++ ++kl++ +++lvG+g++GcE+lKn++l+Gv      g++tv+D d +e+snlnrqFLfr+++++k+K+ +aa+a  +
   Q: 420  YDALRACIGDTLCQKLQKLNIFLVGCGAIGCEMLKNFALLGVgtgkekGMVTVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLK 508
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +np+ +++ah +++++ +e i+   F++k d++++aldn+earr+v+++cl++ +pl++sgt+G++G+++vi+++lte+y++++dpp++
   Q: 509  INPQFKIDAHLNKVCPATEAIYndeFYTKQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEE 597
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk++++++++eevl+k+++ +++eg+++v  +l s++++n+++++e+a+ +f+
   Q: 598  EIPFCTLKSFPAAIEHTIQWArdkfessfshkpSLFNKFWQTYPSAEEVLQKIQTGHSLEGCFQV-IKLLSRRPRNWSQCVELARLKFE 685
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll++f+ d + k++s fw+                                                         +f++
   Q: 686  KYFNHKALQLLHCFPLDTRLKDGSLFWQspkrppspikfdlneplhfsfllnaaklyaavycipfteedlsadallnilsevkiqEFKP 774
           ***************************************************************************************** PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e++ k+e+v  +s++     ++l++++ ++ ++++++++++lsfekddd+  ++d++taa+nlra++++iep +d++++k+
   Q: 775  SNKVVQTDETARKPEQVPISSEDernaiFQLEKAISSNKATTSDLQMAVLSFEKDDDHngHIDFITAASNLRAKMYNIEP-ADRFKTKR 862
           ******************999999********************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           iag+iipaiat +a+v+Gl+a+E+iKv+   +fe++kn+fl++a+
   Q: 863  IAGKIIPAIATSTAAVSGLVALEMIKVAGDyPFEAYKNCFLNLAI 907
           *****************************************9886 PP

Organism

Felis catus

Protein Sequence
(Fasta)

STNTNLPIMS AESVEIDDAL YSRQRYVLGD TAMQKMAKSH VFLSGMGGLG LEIAKNLVLA 60
GIKALTIHDT EKCQAWDLGA NFFLCEDDVV NMRNRAEAVL QHIAELNPYV HVTSSSIPLN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTACCAATA CAAATTTGCC CATCATGTCA GCAGAATCTG TGGAGATTGA TGATGCATTA 60
TACAGGTGAG AACCTTACGG AAACTGAAAC TTATTTTCCT CATTTGTTGT TCTAAAGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	96.11	0.00e+00	2068.00
IUUC-Apl-004158	Anas platyrhynchos	81.25	0.00e+00	1731.00
IUUC-Aca-005349	Anolis carolinensis	80.71	0.00e+00	1769.00
IUUC-Bta-012696	Bos taurus	94.35	0.00e+00	2038.00
IUUC-Cja-019563	Callithrix jacchus	93.78	0.00e+00	1991.00
IUUC-Cfa-020951	Canis familiaris	96.30	0.00e+00	2075.00
IUUC-Cpo-022307	Cavia porcellus	88.81	0.00e+00	1912.00
IUUC-Csa-023647	Chlorocebus sabaeus	94.27	0.00e+00	2009.00
IUUC-Cho-024682	Choloepus hoffmanni	78.78	0.00e+00	956.00
IUUC-Dre-028022	Danio rerio	67.09	0.00e+00	1478.00
IUUC-Dno-029796	Dasypus novemcinctus	92.12	0.00e+00	1968.00
IUUC-Dor-030981	Dipodomys ordii	76.19	0.00e+00	1526.00
IUUC-Ete-032514	Echinops telfairi	78.69	0.00e+00	1153.00
IUUC-Eca-033697	Equus caballus	94.66	0.00e+00	2048.00
IUUC-Eeu-035323	Erinaceus europaeus	85.66	0.00e+00	1352.00
IUUC-Fal-036848	Ficedula albicollis	80.90	0.00e+00	1739.00
IUUC-Gmo-039326	Gadus morhua	66.73	0.00e+00	1395.00
IUUC-Gga-040747	Gallus gallus	80.90	0.00e+00	1726.00
IUUC-Gac-041406	Gasterosteus aculeatus	67.48	0.00e+00	1404.00
IUUC-Ggo-044577	Gorilla gorilla	93.59	0.00e+00	1998.00
IUUC-Hsa-046007	Homo sapiens	93.59	0.00e+00	1991.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	94.38	0.00e+00	1057.00
IUUC-Lch-049992	Latimeria chalumnae	73.31	0.00e+00	1549.00
IUUC-Loc-051899	Lepisosteus oculatus	69.18	0.00e+00	1503.00
IUUC-Laf-054413	Loxodonta africana	93.03	0.00e+00	1881.00
IUUC-Mcc-054656	Macaca mulatta	94.27	0.00e+00	2006.00
IUUC-Meu-056463	Macropus eugenii	71.73	0.00e+00	1420.00
IUUC-Mga-059721	Meleagris gallopavo	80.41	0.00e+00	1629.00
IUUC-Mmr-060908	Microcebus murinus	90.57	0.00e+00	1942.00
IUUC-Mdo-062096	Monodelphis domestica	86.10	0.00e+00	1889.00
IUUC-Mmu-064114	Mus musculus	90.93	0.00e+00	1966.00
IUUC-Mpu-066017	Mustela putorius furo	96.02	0.00e+00	2078.00
IUUC-Mlu-068037	Myotis lucifugus	91.59	0.00e+00	1942.00
IUUC-Nle-069494	Nomascus leucogenys	93.39	0.00e+00	1987.00
IUUC-Opr-070910	Ochotona princeps	67.09	3.00e-175	609.00
IUUC-Ont-071592	Oreochromis niloticus	68.43	0.00e+00	1451.00
IUUC-Oan-073268	Ornithorhynchus anatinus	80.71	0.00e+00	1602.00
IUUC-Ocu-074296	Oryctolagus cuniculus	93.85	0.00e+00	2024.00
IUUC-Ola-086376	Oryzias latipes	69.05	0.00e+00	1415.00
IUUC-Oga-088186	Otolemur garnettii	92.61	0.00e+00	1977.00
IUUC-Oar-089307	Ovis aries	94.55	0.00e+00	2038.00
IUUC-Ptr-090609	Pan troglodytes	93.88	0.00e+00	1993.00
IUUC-Pan-092905	Papio anubis	93.91	0.00e+00	1908.00
IUUC-Psi-093489	Pelodiscus sinensis	82.43	0.00e+00	1768.00
IUUC-Pma-094203	Petromyzon marinus	66.22	1.00e-57	214.00
IUUC-Pfo-096670	Poecilia formosa	69.28	0.00e+00	1474.00
IUUC-Pab-098418	Pongo abelii	93.88	0.00e+00	1993.00
IUUC-Pca-100889	Procavia capensis	76.56	0.00e+00	1594.00
IUUC-Pva-103144	Pteropus vampyrus	82.80	0.00e+00	1740.00
IUUC-Rno-105612	Rattus norvegicus	91.22	0.00e+00	1968.00
IUUC-Sha-107388	Sarcophilus harrisii	86.71	0.00e+00	1881.00
IUUC-Sar-113128	Sorex araneus	89.68	0.00e+00	1949.00
IUUC-Ssc-116117	Sus scrofa	94.56	0.00e+00	2041.00
IUUC-Tgu-116565	Taeniopygia guttata	81.21	0.00e+00	1750.00
IUUC-Tru-118591	Takifugu rubripes	67.35	0.00e+00	1426.00
IUUC-Tsy-119436	Tarsius syrichta	82.92	0.00e+00	1703.00
IUUC-Tni-120880	Tetraodon nigroviridis	66.73	0.00e+00	1409.00
IUUC-Tbe-127714	Tupaia belangeri	80.23	0.00e+00	1412.00
IUUC-Ttr-129159	Tursiops truncatus	81.73	0.00e+00	1696.00
IUUC-Vpa-130716	Vicugna pacos	91.76	0.00e+00	1924.00
IUUC-Xtr-132947	Xenopus tropicalis	70.34	0.00e+00	1538.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence