iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107026

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01009390

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000012441.1	ENSSHAT00000014695.1	ENSSHAP00000014573.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-89	300.8	50	366

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           tGl+NlgNtCYmN++LQcL +i++l e++l+ k+  +l     ++++ge +++++ l++ +w +++  vsp+ + +a++k+ + f +  
   Q: 50   TGLRNLGNTCYMNAILQCLCSITPLVEYFLSgKYITAL-----QKDSGEAATAFAYLMTDMWLGDSDCVSPEVFRAAIGKIYPAFLKRT 133
           7******************************2222222.....5789****************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           qqDaqEfl ++l++l+e+lkk       + ++++++ ls +  +k  ++++s+i++lF+gql  +i+cl+c+n + ++e f+ lslp+p
   Q: 134  QQDAQEFLIYVLNELHEALKK------YRRKKTQENGLSTKCYRKVASSESSIITRLFEGQLNYDIVCLKCENCTYKNEVFTVLSLPIP 216
           *******************44......23333444688999999********************************************* PP
   S: 178  gkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfc 265
           ++ e+   slq+cL  f+++++l+ +n+++c  c++kq+a  + ++ k P++ i+hLkRf  ++++ +++k+ + +++pl+ Ldlsp+ 
   Q: 217  SECEC---SLQECLGCFFQQDTLTWNNQIHCAFCESKQDAAVRASIAKAPKTVIFHLKRF--DCQGRVKRKLRTDIHYPLNnLDLSPYI 300
           *****...****************************************************..99999********************** PP
   S: 266  tspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
               +k   + kY+L++vv+H G l++GHY+a++kn+ ++ W+ fdD++V e++ + v++   + aY+lfY 
   Q: 301  YPLFRK---HPKYSLCGVVNHFGDLDGGHYTAFCKNTVNQtWYSFDDTRVCEIPDSAVQT---AAAYLLFYS 366
           994443...89*************************98888*******************...********6 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

FIERSCCHPA PQNHLSFSLW HKHSTECTDY SDTSSVKESS MAQQHSQGVT GLRNLGNTCY 60
MNAILQCLCS ITPLVEYFLS GKYITALQKD SGEAATAFAY LMTDMWLGDS DCVSPEVFRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCATCGAGC GGAGTTGTTG CCATCCTGCC CCTCAAAATC ATCTCTCTTT TTCCCTGTGG 60
CACAAACACA GCACAGAATG TACAGATTAT AGTGACACCA GCTCTGTCAA AGAGTCTAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	74.46	6.00e-167	579.00
IUUC-Aca-005256	Anolis carolinensis	54.91	4.00e-102	364.00
IUUC-Bta-012753	Bos taurus	74.72	2.00e-160	557.00
IUUC-Cfa-020054	Canis familiaris	75.23	6.00e-150	523.00
IUUC-Cpo-021375	Cavia porcellus	71.35	3.00e-155	541.00
IUUC-Csa-023902	Chlorocebus sabaeus	77.11	2.00e-88	317.00
IUUC-Cho-024755	Choloepus hoffmanni	67.81	2.00e-124	438.00
IUUC-Dor-030311	Dipodomys ordii	75.27	2.00e-82	298.00
IUUC-Ete-032570	Echinops telfairi	60.62	3.00e-96	344.00
IUUC-Eca-034343	Equus caballus	75.00	2.00e-171	594.00
IUUC-Eeu-034510	Erinaceus europaeus	75.24	6.00e-149	519.00
IUUC-Fca-035920	Felis catus	76.09	6.00e-169	586.00
IUUC-Fal-036903	Ficedula albicollis	59.75	3.00e-109	387.00
IUUC-Ggo-045650	Gorilla gorilla	53.58	4.00e-87	314.00
IUUC-Hsa-046665	Homo sapiens	71.39	2.00e-138	484.00
IUUC-Itr-048167	Ictidomys tridecemlineatus	80.91	4.00e-176	610.00
IUUC-Lch-049925	Latimeria chalumnae	53.54	2.00e-106	378.00
IUUC-Loc-051880	Lepisosteus oculatus	49.54	2.00e-80	293.00
IUUC-Laf-054494	Loxodonta africana	80.46	1.00e-172	598.00
IUUC-Mcc-055507	Macaca mulatta	74.58	4.00e-159	553.00
IUUC-Meu-055906	Macropus eugenii	92.83	5.00e-178	616.00
IUUC-Mmr-061564	Microcebus murinus	56.29	9.00e-90	322.00
IUUC-Mdo-061800	Monodelphis domestica	96.02	0.00e+00	705.00
IUUC-Mmu-063618	Mus musculus	69.87	1.00e-163	568.00
IUUC-Mpu-066699	Mustela putorius furo	75.54	9.00e-170	588.00
IUUC-Mlu-067672	Myotis lucifugus	76.64	8.00e-166	575.00
IUUC-Opr-070949	Ochotona princeps	76.01	1.00e-134	471.00
IUUC-Oan-073725	Ornithorhynchus anatinus	69.01	2.00e-146	511.00
IUUC-Ocu-074021	Oryctolagus cuniculus	78.92	1.00e-172	598.00
IUUC-Oga-088258	Otolemur garnettii	76.85	8.00e-150	522.00
IUUC-Oar-089881	Ovis aries	76.92	4.00e-166	577.00
IUUC-Ptr-090988	Pan troglodytes	72.27	3.00e-134	471.00
IUUC-Pan-091773	Papio anubis	78.25	4.00e-169	587.00
IUUC-Psi-093243	Pelodiscus sinensis	73.35	2.00e-142	498.00
IUUC-Pab-097713	Pongo abelii	74.55	1.00e-149	521.00
IUUC-Pca-100226	Procavia capensis	60.59	7.00e-115	406.00
IUUC-Pva-103172	Pteropus vampyrus	78.06	8.00e-152	529.00
IUUC-Rno-105950	Rattus norvegicus	77.78	3.00e-165	574.00
IUUC-Ssc-116383	Sus scrofa	78.69	1.00e-171	595.00
IUUC-Tgu-116511	Taeniopygia guttata	58.46	2.00e-104	371.00
IUUC-Tbe-127808	Tupaia belangeri	75.00	1.00e-57	216.00
IUUC-Ttr-129046	Tursiops truncatus	73.75	5.00e-142	496.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence