iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073076

Ensembl Protein ID

ENSOANP00000004227.1

UniProt Accession

F7B6C6; F7B6C6_ORNAN

Protein Name

Uncharacterized protein

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000002654.2	ENSOANT00000004228.2	ENSOANP00000004227.1
ENSOANG00000002654.2	ENSOANT00000004229.2	ENSOANP00000004228.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.20e-16	58.9	282	338

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ i ++e ++gW+kg + + g+ Gl P+n+ve ++
   Q: 282  RVRALYDYEGQEHDELSFKAGDELTKI-EDEDEQGWCKG-RLDGGQVGLYPANYVEAIQ 338
           699************************.9**********.5999***********9885 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

VEAAKKAYHA ACKEEKLAIS RETNSKADPS LNPEQLKKLQ DKVEKCKQDV LKTKEKYEKS 60
LKELDQGTPQ YMENMEQMFE QCQQFEEKRL RFFREVLLEV QKHLDLSNAV SYKTIYRDME 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCAGCAGC TGGAAATGTG ATGATGTTTA AAATTCTGCC CTTAGGTGGA GGCTGCGAAG 60
AAAGCCTACC ATGCTGCTTG CAAAGAGGAG AAGTTGGCGA TATCAAGGGA AACGAATAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome
GO:0030100--P:regulation of endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	84.32	1.00e-157	549.00
IUUC-Apl-003574	Anas platyrhynchos	81.60	2.00e-149	521.00
IUUC-Aca-004251	Anolis carolinensis	78.87	1.00e-143	501.00
IUUC-Bta-013193	Bos taurus	81.95	1.00e-144	505.00
IUUC-Cja-018756	Callithrix jacchus	82.57	1.00e-146	512.00
IUUC-Cfa-020545	Canis familiaris	85.21	3.00e-159	554.00
IUUC-Cpo-022000	Cavia porcellus	81.45	2.00e-164	571.00
IUUC-Csa-024030	Chlorocebus sabaeus	80.43	3.00e-144	504.00
IUUC-Csv-026244	Ciona savignyi	40.52	6.00e-52	196.00
IUUC-Dno-029429	Dasypus novemcinctus	81.38	3.00e-144	505.00
IUUC-Dor-030122	Dipodomys ordii	78.90	2.00e-140	491.00
IUUC-Eca-033367	Equus caballus	84.59	2.00e-156	545.00
IUUC-Eeu-034821	Erinaceus europaeus	72.46	2.00e-127	448.00
IUUC-Fca-036079	Felis catus	84.32	8.00e-158	549.00
IUUC-Fal-036682	Ficedula albicollis	81.60	2.00e-149	521.00
IUUC-Gga-040717	Gallus gallus	81.90	2.00e-150	525.00
IUUC-Ggo-044841	Gorilla gorilla	81.35	1.00e-144	505.00
IUUC-Hsa-046411	Homo sapiens	81.04	4.00e-144	504.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	82.57	1.00e-149	522.00
IUUC-Laf-053839	Loxodonta africana	81.45	8.00e-154	536.00
IUUC-Mcc-055783	Macaca mulatta	81.04	2.00e-144	505.00
IUUC-Mga-060087	Meleagris gallopavo	73.59	2.00e-129	455.00
IUUC-Mvi-060548	Microbotryum violaceum	41.51	3.00e-07	50.80
IUUC-Mmr-060827	Microcebus murinus	83.83	4.00e-155	540.00
IUUC-Mmu-064109	Mus musculus	83.53	1.00e-154	539.00
IUUC-Mpu-066591	Mustela putorius furo	85.21	1.00e-159	555.00
IUUC-Mlu-067826	Myotis lucifugus	83.14	8.00e-156	542.00
IUUC-Nle-069797	Nomascus leucogenys	81.65	4.00e-145	507.00
IUUC-Ocu-074425	Oryctolagus cuniculus	84.31	6.00e-151	526.00
IUUC-Oga-089009	Otolemur garnettii	81.09	1.00e-148	519.00
IUUC-Oar-089806	Ovis aries	82.54	1.00e-145	509.00
IUUC-Ptr-091111	Pan troglodytes	80.73	5.00e-143	500.00
IUUC-Pan-091749	Papio anubis	81.04	1.00e-144	505.00
IUUC-Psi-093704	Pelodiscus sinensis	81.01	9.00e-152	529.00
IUUC-Pab-098584	Pongo abelii	81.35	2.00e-144	504.00
IUUC-Pva-102649	Pteropus vampyrus	81.04	5.00e-146	510.00
IUUC-Rno-105431	Rattus norvegicus	81.84	3.00e-156	544.00
IUUC-Sha-106641	Sarcophilus harrisii	83.48	7.00e-152	529.00
IUUC-Sar-113461	Sorex araneus	70.12	3.00e-124	437.00
IUUC-Ssc-115349	Sus scrofa	84.27	7.00e-148	516.00
IUUC-Tgu-116876	Taeniopygia guttata	81.90	5.00e-150	523.00
IUUC-Tsy-118901	Tarsius syrichta	79.88	1.00e-146	512.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence