iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027440

Ensembl Protein ID

ENSDARP00000123759.1

UniProt Accession

F8W580; F8W580_DANRE

Genbank Protein ID

ENSDARP00000123759

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

CT027748

Gene Name

kmt2bb; mll4b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000060697.9	ENSDART00000148870.2	ENSDARP00000123759.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.50e-20	71.6	1786	1844

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek...slveCekCrewfHpaClkls.....veeelpnsekwiCpkCr 52
           ++C +C++++ed++   ++++C+ C++w+H++C +l+     + ++lp+s  + C+ C 
   Q: 1786 NYCTMCFKCYEDNDydsQMMQCSTCNHWVHAKCEGLTddlyeILSSLPESVVYSCQPCL 1844
           79*********998888*****************************************6 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MMAAAGCGSA TAAAVVGAGG VGAARGRFPG RPWSSRSRLR SEKRWQLGRC GTDLDEISAN 60
GGPRPTCLVL APNEDQPLSR LLGLEASYKR LGEAGYSSSG SEEGSEFKGF EVQNENRSIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTTTTGGA CAATTTTAAA AAGCCTTTTT GATCCATTTG TTTACTACTA TATATCGTTC 60
TCTTGTGATA TATAAAACAA CAATATTTTC CATAAACTAG ATCGACGTTG TGGACGCGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

KEGG

dre:566825

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002367	Ailuropoda melanoleuca	48.63	0.00e+00	780.00
IUUC-Atr-002455	Amborella trichopoda	39.09	8.00e-40	159.00
IUUC-Aca-004718	Anolis carolinensis	44.73	0.00e+00	998.00
IUUC-Ame-010705	Astyanax mexicanus	59.54	0.00e+00	3821.00
IUUC-Bta-013578	Bos taurus	51.27	0.00e+00	779.00
IUUC-Bdi-014882	Brachypodium distachyon	32.47	1.00e-26	115.00
IUUC-Cja-019138	Callithrix jacchus	51.79	0.00e+00	771.00
IUUC-Cfa-020020	Canis familiaris	51.31	0.00e+00	768.00
IUUC-Cre-022891	Chlamydomonas reinhardtii	52.34	5.00e-38	154.00
IUUC-Csa-024216	Chlorocebus sabaeus	51.52	0.00e+00	766.00
IUUC-Dno-029583	Dasypus novemcinctus	48.63	0.00e+00	792.00
IUUC-Dor-030903	Dipodomys ordii	48.34	0.00e+00	775.00
IUUC-Dme-032023	Drosophila melanogaster	48.99	5.00e-96	348.00
IUUC-Eca-034026	Equus caballus	48.53	0.00e+00	777.00
IUUC-Eeu-034687	Erinaceus europaeus	64.72	2.00e-158	554.00
IUUC-Fca-036311	Felis catus	50.73	0.00e+00	776.00
IUUC-Gmo-039265	Gadus morhua	56.89	0.00e+00	2300.00
IUUC-Gac-042202	Gasterosteus aculeatus	54.96	0.00e+00	2236.00
IUUC-Ggo-044791	Gorilla gorilla	51.38	0.00e+00	763.00
IUUC-Hsa-046988	Homo sapiens	51.24	0.00e+00	766.00
IUUC-Hvu-047762	Hordeum vulgare	32.92	3.00e-19	90.10
IUUC-Itr-048907	Ictidomys tridecemlineatus	51.40	0.00e+00	791.00
IUUC-Lpe-051476	Leersia perrieri	32.26	2.00e-23	104.00
IUUC-Loc-052252	Lepisosteus oculatus	60.68	0.00e+00	1322.00
IUUC-Mcc-054782	Macaca mulatta	50.61	0.00e+00	760.00
IUUC-Mmr-061316	Microcebus murinus	51.27	0.00e+00	779.00
IUUC-Mmu-063579	Mus musculus	51.27	0.00e+00	783.00
IUUC-Nle-070085	Nomascus leucogenys	51.38	0.00e+00	761.00
IUUC-Opr-071148	Ochotona princeps	51.00	0.00e+00	777.00
IUUC-Ont-071626	Oreochromis niloticus	52.96	0.00e+00	2422.00
IUUC-Ocu-074475	Oryctolagus cuniculus	50.40	0.00e+00	754.00
IUUC-Obr-076458	Oryza brachyantha	34.36	2.00e-28	120.00
IUUC-Ogl-077851	Oryza glaberrima	32.90	3.00e-27	117.00
IUUC-Ogu-078706	Oryza glumaepatula	34.16	4.00e-27	117.00
IUUC-Oin-079802	Oryza indica	30.00	4.00e-22	100.00
IUUC-Osa-085421	Oryza sativa	34.16	1.00e-26	115.00
IUUC-Ola-086609	Oryzias latipes	58.53	0.00e+00	1385.00
IUUC-Oga-088140	Otolemur garnettii	51.27	0.00e+00	780.00
IUUC-Ptr-090902	Pan troglodytes	51.38	0.00e+00	764.00
IUUC-Pan-091930	Papio anubis	51.38	0.00e+00	765.00
IUUC-Ppa-095221	Physcomitrella patens	33.73	7.00e-32	132.00
IUUC-Pva-102634	Pteropus vampyrus	48.39	0.00e+00	777.00
IUUC-Rno-105870	Rattus norvegicus	51.27	0.00e+00	790.00
IUUC-Sit-110552	Setaria italica	32.77	1.00e-28	121.00
IUUC-Sar-113289	Sorex araneus	47.40	0.00e+00	675.00
IUUC-Ssc-115509	Sus scrofa	51.94	0.00e+00	772.00
IUUC-Tru-118413	Takifugu rubripes	61.46	0.00e+00	1301.00
IUUC-Tni-119794	Tetraodon nigroviridis	56.13	0.00e+00	879.00
IUUC-Tae-125629	Triticum aestivum	32.92	2.00e-19	90.50
IUUC-Tbe-127825	Tupaia belangeri	77.53	3.00e-149	524.00
IUUC-Vvi-131476	Vitis vinifera	39.51	4.00e-39	157.00
IUUC-Xtr-132838	Xenopus tropicalis	39.17	0.00e+00	739.00
IUUC-Xma-133119	Xiphophorus maculatus	53.61	0.00e+00	1508.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence