iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000004646.1	ENSOART00000005052.1	ENSOARP00000004967.1
ENSOARG00000004646.1	ENSOART00000005054.1	ENSOARP00000004969.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.90e-10	40.3	16	66

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw.....pglknssskefrCPlCr 46
           C+iCl+ f d p+ + CgH f+++C+   w     + + ++ +++f CP Cr
   Q: 16   CSICLDYFTD-PVMTTCGHNFCRECIqLTWekakgQKKRRKRKGSFPCPECR 66
           **********.999************888899999888889**********8 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MDAVELARKL QEEATCSICL DYFTDPVMTT CGHNFCRECI QLTWEKAKGQ KKRRKRKGSF 60
PCPECRELSP QRNNLRPNRP LAKMAEMARR LHPPSPVPQG VCAAHREPLA AFCGDELRLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCGCTCCCT GCCGCCCCGC ACGCCTTCCC CTCCGCAGAC AAGGCTCCCA CCACCGTCTA 60
CCCCTCCCCC TTCCCGCCTG ACTGCCTAAC CCCTGCCCTG TTCCCGCTCC TTCCGCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0050768--P:negative regulation of neurogenesis
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0046598--P:positive regulation of viral entry into host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001800	Ailuropoda melanoleuca	80.09	0.00e+00	631.00
IUUC-Bta-012332	Bos taurus	91.84	0.00e+00	782.00
IUUC-Cja-019969	Callithrix jacchus	73.43	1.00e-171	596.00
IUUC-Cfa-020491	Canis familiaris	89.12	0.00e+00	775.00
IUUC-Cpo-021936	Cavia porcellus	80.54	0.00e+00	683.00
IUUC-Csa-024151	Chlorocebus sabaeus	84.94	0.00e+00	675.00
IUUC-Cho-024990	Choloepus hoffmanni	68.58	4.00e-96	343.00
IUUC-Dno-029580	Dasypus novemcinctus	74.50	1.00e-167	582.00
IUUC-Ete-032556	Echinops telfairi	64.34	2.00e-103	369.00
IUUC-Eca-033612	Equus caballus	80.61	3.00e-146	511.00
IUUC-Fca-035821	Felis catus	95.47	7.00e-163	566.00
IUUC-Ggo-044629	Gorilla gorilla	85.15	0.00e+00	679.00
IUUC-Hsa-046332	Homo sapiens	85.15	0.00e+00	679.00
IUUC-Itr-047946	Ictidomys tridecemlineatus	83.26	0.00e+00	689.00
IUUC-Laf-054350	Loxodonta africana	74.75	2.00e-143	501.00
IUUC-Mcc-055827	Macaca mulatta	83.68	0.00e+00	658.00
IUUC-Meu-056122	Macropus eugenii	66.04	2.00e-172	598.00
IUUC-Mmr-061700	Microcebus murinus	83.23	0.00e+00	701.00
IUUC-Mdo-062921	Monodelphis domestica	57.32	6.00e-145	507.00
IUUC-Mmu-063762	Mus musculus	79.92	0.00e+00	657.00
IUUC-Mpu-065873	Mustela putorius furo	89.12	0.00e+00	775.00
IUUC-Mlu-067379	Myotis lucifugus	75.96	0.00e+00	652.00
IUUC-Nle-069440	Nomascus leucogenys	84.65	0.00e+00	675.00
IUUC-Opr-070901	Ochotona princeps	74.89	9.00e-161	559.00
IUUC-Ocu-074038	Oryctolagus cuniculus	74.73	2.00e-164	572.00
IUUC-Oga-088948	Otolemur garnettii	78.46	0.00e+00	671.00
IUUC-Ptr-090615	Pan troglodytes	88.94	5.00e-99	354.00
IUUC-Pan-092626	Papio anubis	84.94	0.00e+00	676.00
IUUC-Pab-097895	Pongo abelii	79.29	0.00e+00	674.00
IUUC-Pca-100435	Procavia capensis	82.81	0.00e+00	686.00
IUUC-Pva-102288	Pteropus vampyrus	78.24	0.00e+00	639.00
IUUC-Rno-105938	Rattus norvegicus	80.13	0.00e+00	665.00
IUUC-Sha-107354	Sarcophilus harrisii	69.96	3.00e-179	621.00
IUUC-Ssc-115951	Sus scrofa	49.78	4.00e-105	374.00
IUUC-Tbe-127733	Tupaia belangeri	85.05	0.00e+00	697.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence