iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108319

Ensembl Protein ID

SPCC162.07.1:pep

UniProt Accession

O74423; ENT1_SCHPO

Genbank Protein ID

CAA19587.1

Protein Name

Epsin-1

Genbank Nucleotide ID

CU329672

Gene Name

ent1; SPCC162.07

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPCC162.07	SPCC162.07.1	SPCC162.07.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UIM	53.24	8.00e-42	167.00	IUUC-Sce-106406

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.

Protein Sequence
(Fasta)

MKAAVRSVKN FSKGYTDTQI KVRNATTNDS WGPSGTAMAE IAELTYDQNE MLEVMDIIDR 60
RLNDKGKNWR HVFKSLSLLE YCLHNGSENV VRWAKDNIYI ITTLREFVYV DDNGHDQGQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCAACCTT AACCATAACC CATCAGCAGT GTTGCCGAAG TAGGGAAAGA AGGACGATAG 60
AGCATATAGC TTGGTGATTT TTCAGAAGGA TTTGGAATTT GCATATTAAC GAGACATTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0254--Endocytosis
KW-0446--Lipid-binding
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR013182--DUF1720
IPR013809--ENTH
IPR008942--ENTH_VHS
IPR003903--UIM_dom

PROSITE

PS50942--ENTH
PS50330--UIM

Pfam

PF08226--DUF1720
PF01417--ENTH

SMART

SM00273--ENTH
SM00726--UIM

Gene Ontology

GO:0030479--C:actin cortical patch
GO:0016020--C:membrane
GO:0030276--F:clathrin binding
GO:0005546--F:phosphatidylinositol-4,5-bisphosphate binding
GO:0043130--F:ubiquitin binding
GO:0000147--P:actin cortical patch assembly
GO:0007015--P:actin filament organization
GO:0006897--P:endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000113	Aegilops tauschii	41.46	3.00e-30	125.00
IUUC-Aml-002304	Ailuropoda melanoleuca	51.20	5.00e-38	150.00
IUUC-Atr-002956	Amborella trichopoda	43.80	1.00e-31	129.00
IUUC-Apl-003474	Anas platyrhynchos	52.24	9.00e-42	162.00
IUUC-Aca-005208	Anolis carolinensis	53.33	1.00e-42	166.00
IUUC-Aly-006457	Arabidopsis lyrata	41.32	5.00e-30	124.00
IUUC-Ath-007675	Arabidopsis thaliana	42.15	3.00e-30	125.00
IUUC-Ago-007809	Ashbya gossypii	45.60	6.00e-31	126.00
IUUC-Acl-008167	Aspergillus clavatus	63.91	1.00e-51	195.00
IUUC-Afl-008626	Aspergillus flavus	63.49	1.00e-47	181.00
IUUC-Afu-009110	Aspergillus fumigatus	63.91	4.00e-52	197.00
IUUC-Ani-009183	Aspergillus nidulans	62.41	7.00e-51	192.00
IUUC-Ang-009835	Aspergillus niger	64.66	2.00e-52	198.00
IUUC-Aor-009899	Aspergillus oryzae	65.41	2.00e-52	197.00
IUUC-Ate-010292	Aspergillus terreus	63.91	3.00e-52	197.00
IUUC-Ame-010832	Astyanax mexicanus	56.30	2.00e-43	168.00
IUUC-Bgr-012103	Blumeria graminis	62.86	8.00e-54	202.00
IUUC-Bta-013258	Bos taurus	52.24	6.00e-42	163.00
IUUC-Bci-013887	Botrytis cinerea	63.91	7.00e-52	196.00
IUUC-Bdi-014129	Brachypodium distachyon	42.28	2.00e-31	129.00
IUUC-Bol-016058	Brassica oleracea	43.80	3.00e-31	128.00
IUUC-Bra-017893	Brassica rapa	42.15	5.00e-30	124.00
IUUC-Cel-018350	Caenorhabditis elegans	51.49	5.00e-39	153.00
IUUC-Cja-019818	Callithrix jacchus	50.75	3.00e-41	161.00
IUUC-Cfa-020229	Canis familiaris	50.75	2.00e-41	161.00
IUUC-Cpo-021844	Cavia porcellus	53.97	1.00e-38	152.00
IUUC-Csa-023208	Chlorocebus sabaeus	51.20	7.00e-38	149.00
IUUC-Cho-024649	Choloepus hoffmanni	43.61	7.00e-34	136.00
IUUC-Cin-025755	Ciona intestinalis	50.40	3.00e-37	146.00
IUUC-Csv-025907	Ciona savignyi	50.40	2.00e-37	148.00
IUUC-Cgl-026614	Colletotrichum gloeosporioides	61.43	1.00e-53	202.00
IUUC-Cne-027047	Cryptococcus neoformans	71.21	4.00e-57	213.00
IUUC-Cme-027132	Cyanidioschyzon merolae	41.67	4.00e-16	77.40
IUUC-Dre-028015	Danio rerio	50.40	3.00e-38	150.00
IUUC-Dno-029660	Dasypus novemcinctus	51.49	3.00e-41	161.00
IUUC-Dor-030230	Dipodomys ordii	50.75	2.00e-41	161.00
IUUC-Dse-031529	Dothistroma septosporum	60.71	9.00e-53	199.00
IUUC-Dme-032149	Drosophila melanogaster	55.22	8.00e-42	163.00
IUUC-Ete-032944	Echinops telfairi	50.75	5.00e-41	160.00
IUUC-Eca-034189	Equus caballus	51.20	4.00e-38	150.00
IUUC-Eeu-034710	Erinaceus europaeus	47.01	9.00e-38	149.00
IUUC-Fca-036270	Felis catus	51.20	5.00e-38	150.00
IUUC-Fal-036640	Ficedula albicollis	52.24	7.00e-42	163.00
IUUC-Fox-037900	Fusarium oxysporum	64.08	2.00e-38	152.00
IUUC-Fso-038083	Fusarium solani	57.14	3.00e-46	177.00
IUUC-Gmo-038468	Gadus morhua	52.99	1.00e-40	158.00
IUUC-Ggr-039910	Gaeumannomyces graminis	63.57	1.00e-53	202.00
IUUC-Gga-040781	Gallus gallus	52.24	5.00e-42	163.00
IUUC-Gac-042085	Gasterosteus aculeatus	49.60	1.00e-37	149.00
IUUC-Gma-042967	Glycine max	44.17	2.00e-31	129.00
IUUC-Ggo-044421	Gorilla gorilla	50.75	2.00e-41	161.00
IUUC-Hsa-046033	Homo sapiens	51.20	6.00e-38	150.00
IUUC-Hvu-047135	Hordeum vulgare	41.13	4.00e-30	124.00
IUUC-Itr-048041	Ictidomys tridecemlineatus	51.20	5.00e-38	150.00
IUUC-Kpa-049233	Komagataella pastoris	58.14	9.00e-44	169.00
IUUC-Lch-050652	Latimeria chalumnae	52.90	2.00e-41	162.00
IUUC-Lpe-051296	Leersia perrieri	43.33	4.00e-32	131.00
IUUC-Loc-052572	Lepisosteus oculatus	51.85	5.00e-41	160.00
IUUC-Lma-053140	Leptosphaeria maculans	61.65	3.00e-50	192.00
IUUC-Laf-054571	Loxodonta africana	51.20	5.00e-38	150.00
IUUC-Mcc-055036	Macaca mulatta	51.20	7.00e-38	149.00
IUUC-Meu-056064	Macropus eugenii	52.17	3.00e-41	161.00
IUUC-Mor-057254	Magnaporthe oryzae	63.57	7.00e-54	202.00
IUUC-Mpo-057426	Magnaporthe poae	37.50	8.00e-04	36.60
IUUC-Mtr-058328	Medicago truncatula	44.63	9.00e-32	130.00
IUUC-Mla-058947	Melampsora laricipopulina	59.57	5.00e-50	189.00
IUUC-Mga-060111	Meleagris gallopavo	52.24	7.00e-42	163.00
IUUC-Mvi-060293	Microbotryum violaceum	61.59	1.00e-51	195.00
IUUC-Mmr-060634	Microcebus murinus	51.20	5.00e-38	150.00
IUUC-Mdo-061941	Monodelphis domestica	52.24	2.00e-41	161.00
IUUC-Mmu-063799	Mus musculus	51.20	6.00e-38	150.00
IUUC-Mac-064643	Musa acuminata	44.63	1.00e-31	129.00
IUUC-Mpu-066803	Mustela putorius furo	51.20	4.00e-38	150.00
IUUC-Mlu-067895	Myotis lucifugus	51.20	1.00e-37	149.00
IUUC-Nfi-068548	Neosartorya fischeri	63.91	4.00e-52	197.00
IUUC-Ncr-068627	Neurospora crassa	59.38	2.00e-46	178.00
IUUC-Nle-069810	Nomascus leucogenys	51.20	7.00e-38	149.00
IUUC-Opr-070654	Ochotona princeps	50.72	8.00e-41	159.00
IUUC-Ont-072334	Oreochromis niloticus	55.56	2.00e-43	168.00
IUUC-Oan-073743	Ornithorhynchus anatinus	52.24	6.00e-42	163.00
IUUC-Ocu-074139	Oryctolagus cuniculus	50.75	4.00e-41	160.00
IUUC-Oba-075922	Oryza barthii	43.33	5.00e-31	127.00
IUUC-Obr-076552	Oryza brachyantha	42.50	3.00e-30	125.00
IUUC-Ogl-077885	Oryza glaberrima	43.33	5.00e-31	127.00
IUUC-Ogu-078795	Oryza glumaepatula	43.33	5.00e-31	127.00
IUUC-Oin-080196	Oryza indica	43.33	6.00e-31	127.00
IUUC-Olo-080509	Oryza longistaminata	43.33	5.00e-31	127.00
IUUC-Ome-081531	Oryza meridionalis	43.33	5.00e-31	127.00
IUUC-Oni-083003	Oryza nivara	43.33	6.00e-31	127.00
IUUC-Opu-083829	Oryza punctata	43.33	7.00e-31	127.00
IUUC-Oru-084248	Oryza rufipogon	43.33	6.00e-31	127.00
IUUC-Osa-085910	Oryza sativa	43.33	6.00e-31	127.00
IUUC-Ola-087447	Oryzias latipes	50.40	3.00e-38	150.00
IUUC-Olu-087896	Ostreococcus lucimarinus	34.29	5.00e-18	82.00
IUUC-Oga-088369	Otolemur garnettii	51.20	6.00e-38	150.00
IUUC-Oar-090233	Ovis aries	52.24	5.00e-42	164.00
IUUC-Ptr-091336	Pan troglodytes	51.20	8.00e-38	149.00
IUUC-Pan-092050	Papio anubis	50.75	3.00e-41	161.00
IUUC-Psi-093688	Pelodiscus sinensis	52.24	9.00e-42	162.00
IUUC-Pma-094335	Petromyzon marinus	50.40	1.00e-37	149.00
IUUC-Pno-095066	Phaeosphaeria nodorum	64.22	2.00e-41	161.00
IUUC-Ppa-095284	Physcomitrella patens	43.20	1.00e-31	129.00
IUUC-Pfo-097478	Poecilia formosa	55.97	1.00e-43	169.00
IUUC-Pab-098722	Pongo abelii	51.20	5.00e-38	150.00
IUUC-Pop-098881	Populus trichocarpa	42.98	8.00e-31	127.00
IUUC-Pca-100297	Procavia capensis	51.20	5.00e-38	150.00
IUUC-Ppe-101157	Prunus persica	44.63	4.00e-31	128.00
IUUC-Pva-102611	Pteropus vampyrus	49.28	4.00e-40	157.00
IUUC-Pgr-103451	Puccinia graminis	61.65	3.00e-50	189.00
IUUC-Ptt-103708	Puccinia triticina	63.03	2.00e-46	177.00
IUUC-Pte-104048	Pyrenophora teres	60.90	6.00e-49	186.00
IUUC-Pyt-104596	Pyrenophora triticirepentis	60.90	1.00e-48	186.00
IUUC-Rno-104941	Rattus norvegicus	51.20	7.00e-38	149.00
IUUC-Sce-106406	Saccharomyces cerevisiae	53.24	3.00e-43	167.00
IUUC-Sha-107254	Sarcophilus harrisii	52.24	1.00e-41	162.00
IUUC-Sja-107671	Schizosaccharomyces japonicus	60.37	1.00e-111	395.00
IUUC-Ssl-108625	Sclerotinia sclerotiorum	63.91	9.00e-52	196.00
IUUC-Smo-109370	Selaginella moellendorffii	46.28	1.00e-28	117.00
IUUC-Sit-109784	Setaria italica	42.15	3.00e-30	125.00
IUUC-Sly-111438	Solanum lycopersicum	38.10	3.00e-31	128.00
IUUC-Stu-112874	Solanum tuberosum	38.10	2.00e-31	129.00
IUUC-Sar-113696	Sorex araneus	51.49	1.00e-40	159.00
IUUC-Sbi-114540	Sorghum bicolor	40.50	4.00e-30	124.00
IUUC-Sre-114959	Sporisorium reilianum	67.42	3.00e-54	204.00
IUUC-Ssc-115921	Sus scrofa	50.78	1.00e-37	149.00
IUUC-Tgu-117395	Taeniopygia guttata	51.45	1.00e-41	162.00
IUUC-Tru-117791	Takifugu rubripes	50.40	3.00e-38	151.00
IUUC-Tsy-119034	Tarsius syrichta	45.86	9.00e-37	146.00
IUUC-Tni-120827	Tetraodon nigroviridis	51.49	4.00e-39	154.00
IUUC-Tca-121377	Theobroma cacao	43.80	6.00e-31	127.00
IUUC-Tre-122134	Trichoderma reesei	57.86	2.00e-49	188.00
IUUC-Tvi-122308	Trichoderma virens	58.57	7.00e-51	192.00
IUUC-Tae-122690	Triticum aestivum	41.46	3.00e-30	125.00
IUUC-Tur-126042	Triticum urartu	41.46	3.00e-30	125.00
IUUC-Tme-127215	Tuber melanosporum	62.14	1.00e-54	205.00
IUUC-Tbe-127405	Tupaia belangeri	50.00	1.00e-40	158.00
IUUC-Ttr-128552	Tursiops truncatus	50.72	1.00e-40	159.00
IUUC-Uma-129605	Ustilago maydis	67.42	3.00e-54	204.00
IUUC-Vda-129905	Verticillium dahliae	62.14	5.00e-54	203.00
IUUC-Vpa-130825	Vicugna pacos	45.86	9.00e-37	146.00
IUUC-Vvi-131209	Vitis vinifera	45.45	1.00e-30	125.00
IUUC-Xtr-131804	Xenopus tropicalis	54.07	1.00e-42	166.00
IUUC-Xma-133599	Xiphophorus maculatus	58.12	2.00e-39	155.00
IUUC-Yli-134375	Yarrowia lipolytica	65.12	1.00e-53	202.00
IUUC-Zma-134885	Zea mays	40.50	3.00e-29	121.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence