iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062851

Ensembl Protein ID

ENSMODP00000031347.2

UniProt Accession

F6UVC8; F6UVC8_MONDO

Protein Name

Coronin

Gene Name

CORO1C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000002824.3	ENSMODT00000032919.2	ENSMODP00000031347.2
ENSMODG00000002824.3	ENSMODT00000003507.2	ENSMODP00000003435.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-15	55.3	345	377

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 345  GHTGPVLDIDWcphNDQVIASGSEDCTVMVWQI 377
           8***********977799*************86 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MQTSVWPPRG GAACTRTRAT SDPDEEPPET SRLLRVSSET VWLSRRRQPG PVVYVREESE 60
LHVRSLASTR GPAGPVVSSA RGCLSRQSSG ASDGVPDGGG RQVSRLPCAV AGNWTPEPRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGAGCCCGA GAAGCCGCTG CGTCCGCGGG GGTGGGGGGT GGGGCCGGAA AAAAAGGATC 60
ACCTCCCTCC CCCCCCCCCC CGCCCCAGCA GGCCCCCAAG TCCATCCAGG GATCCCGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027333--CORO1C
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0016328--C:lateral plasma membrane
GO:0031982--C:vesicle
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0010633--P:negative regulation of epithelial cell migration
GO:0051895--P:negative regulation of focal adhesion assembly
GO:0044387--P:negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:1900025--P:negative regulation of substrate adhesion-dependent cell spreading
GO:0001755--P:neural crest cell migration
GO:2000394--P:positive regulation of lamellipodium morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002236	Ailuropoda melanoleuca	86.97	0.00e+00	848.00
IUUC-Apl-003861	Anas platyrhynchos	85.47	0.00e+00	834.00
IUUC-Ame-011256	Astyanax mexicanus	71.73	0.00e+00	682.00
IUUC-Bta-013225	Bos taurus	85.13	0.00e+00	848.00
IUUC-Cja-019948	Callithrix jacchus	85.42	0.00e+00	845.00
IUUC-Cfa-020591	Canis familiaris	85.16	0.00e+00	848.00
IUUC-Cpo-021480	Cavia porcellus	86.92	0.00e+00	844.00
IUUC-Csa-024152	Chlorocebus sabaeus	87.00	0.00e+00	852.00
IUUC-Cho-024687	Choloepus hoffmanni	85.75	0.00e+00	773.00
IUUC-Dre-028541	Danio rerio	74.05	0.00e+00	686.00
IUUC-Dno-029552	Dasypus novemcinctus	86.67	0.00e+00	774.00
IUUC-Eca-034118	Equus caballus	86.97	0.00e+00	847.00
IUUC-Fca-035549	Felis catus	87.13	0.00e+00	845.00
IUUC-Fal-037065	Ficedula albicollis	81.37	0.00e+00	850.00
IUUC-Gmo-038678	Gadus morhua	70.60	0.00e+00	684.00
IUUC-Gga-040842	Gallus gallus	85.47	0.00e+00	838.00
IUUC-Gac-041543	Gasterosteus aculeatus	68.70	0.00e+00	679.00
IUUC-Ggo-044477	Gorilla gorilla	86.21	0.00e+00	851.00
IUUC-Hsa-046610	Homo sapiens	87.00	0.00e+00	851.00
IUUC-Itr-048583	Ictidomys tridecemlineatus	85.95	0.00e+00	847.00
IUUC-Lch-050453	Latimeria chalumnae	75.52	0.00e+00	734.00
IUUC-Loc-052911	Lepisosteus oculatus	74.27	0.00e+00	738.00
IUUC-Laf-053416	Loxodonta africana	86.71	0.00e+00	844.00
IUUC-Mcc-055113	Macaca mulatta	87.18	0.00e+00	849.00
IUUC-Meu-056732	Macropus eugenii	74.95	0.00e+00	655.00
IUUC-Mga-060143	Meleagris gallopavo	85.62	0.00e+00	832.00
IUUC-Mmr-061130	Microcebus murinus	86.95	0.00e+00	846.00
IUUC-Mmu-063663	Mus musculus	85.86	0.00e+00	834.00
IUUC-Mpu-066179	Mustela putorius furo	87.13	0.00e+00	847.00
IUUC-Mlu-068175	Myotis lucifugus	87.39	0.00e+00	849.00
IUUC-Nle-070001	Nomascus leucogenys	86.58	0.00e+00	642.00
IUUC-Opr-070617	Ochotona princeps	86.71	0.00e+00	808.00
IUUC-Ont-072629	Oreochromis niloticus	75.42	0.00e+00	745.00
IUUC-Oan-073547	Ornithorhynchus anatinus	84.96	0.00e+00	827.00
IUUC-Ocu-074569	Oryctolagus cuniculus	86.16	0.00e+00	845.00
IUUC-Ola-086558	Oryzias latipes	72.08	0.00e+00	727.00
IUUC-Oga-089145	Otolemur garnettii	87.37	0.00e+00	848.00
IUUC-Oar-089654	Ovis aries	86.76	0.00e+00	848.00
IUUC-Ptr-090763	Pan troglodytes	87.13	0.00e+00	846.00
IUUC-Pan-091885	Papio anubis	86.46	0.00e+00	805.00
IUUC-Psi-093011	Pelodiscus sinensis	84.21	0.00e+00	824.00
IUUC-Pfo-097309	Poecilia formosa	74.68	0.00e+00	745.00
IUUC-Pab-097542	Pongo abelii	95.16	0.00e+00	865.00
IUUC-Pca-100630	Procavia capensis	72.67	0.00e+00	659.00
IUUC-Rno-105330	Rattus norvegicus	86.29	0.00e+00	840.00
IUUC-Sha-106695	Sarcophilus harrisii	86.83	0.00e+00	682.00
IUUC-Ssc-115348	Sus scrofa	84.43	0.00e+00	842.00
IUUC-Tgu-116597	Taeniopygia guttata	85.47	0.00e+00	833.00
IUUC-Tru-118425	Takifugu rubripes	73.00	0.00e+00	722.00
IUUC-Tsy-119223	Tarsius syrichta	75.40	0.00e+00	635.00
IUUC-Tni-120610	Tetraodon nigroviridis	72.30	0.00e+00	716.00
IUUC-Tbe-127679	Tupaia belangeri	87.57	0.00e+00	640.00
IUUC-Ttr-129226	Tursiops truncatus	85.16	0.00e+00	807.00
IUUC-Vpa-130339	Vicugna pacos	87.09	1.00e-173	602.00
IUUC-Xtr-132873	Xenopus tropicalis	67.58	0.00e+00	650.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence