iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074569

Ensembl Protein ID

ENSOCUP00000019631.1

UniProt Accession

G1TRH5; G1TRH5_RABIT

Protein Name

Coronin

Gene Name

CORO1C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000014233.3	ENSOCUT00000025446.1	ENSOCUP00000019631.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-16	58.6	129	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 129  GHTGPVLDIDWcphNDQVIASGSEDCTVMVWQI 161
           8***********977799*************86 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MYGPSSQLER SGNSWAKEHR LPAACQESVA SAQLNPLLGE RPLLHMSWKD TMRRVVRQSK 60
FRHVFGQAVK NDQCYDDIRV SRVTWDSSFC AVNPRFVAII VEASGGGAFL VLPLHKTGRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTATGGAC CTAGCTCTCA GCTGGAAAGG TCTGGCAACA GCTGGGCTAA GGAGCACAGA 60
CTTCCGGCGG CCTGCCAAGA GTCTGTTGCC TCAGCCCAGC TCAATGCCCT TGCTTGGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027333--CORO1C
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0016600--C:flotillin complex
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0016328--C:lateral plasma membrane
GO:0031982--C:vesicle
GO:0030036--P:actin cytoskeleton organization
GO:0090630--P:activation of GTPase activity
GO:0045184--P:establishment of protein localization
GO:0010633--P:negative regulation of epithelial cell migration
GO:0051895--P:negative regulation of focal adhesion assembly
GO:0044387--P:negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:1900025--P:negative regulation of substrate adhesion-dependent cell spreading
GO:0001755--P:neural crest cell migration
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0010762--P:regulation of fibroblast migration
GO:1900027--P:regulation of ruffle assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002236	Ailuropoda melanoleuca	96.66	0.00e+00	973.00
IUUC-Apl-003861	Anas platyrhynchos	94.53	0.00e+00	949.00
IUUC-Aca-005056	Anolis carolinensis	71.34	0.00e+00	733.00
IUUC-Acl-008280	Aspergillus clavatus	43.32	4.00e-98	352.00
IUUC-Afl-008393	Aspergillus flavus	43.32	5.00e-97	348.00
IUUC-Afu-008865	Aspergillus fumigatus	41.59	5.00e-94	338.00
IUUC-Ani-009155	Aspergillus nidulans	42.86	8.00e-99	354.00
IUUC-Ang-009523	Aspergillus niger	41.09	2.00e-88	319.00
IUUC-Aor-010049	Aspergillus oryzae	42.82	8.00e-94	338.00
IUUC-Ate-010368	Aspergillus terreus	42.61	3.00e-94	338.00
IUUC-Ame-011256	Astyanax mexicanus	80.61	0.00e+00	790.00
IUUC-Bta-013225	Bos taurus	91.63	0.00e+00	974.00
IUUC-Bci-013935	Botrytis cinerea	43.28	2.00e-100	359.00
IUUC-Cja-019948	Callithrix jacchus	92.80	0.00e+00	1016.00
IUUC-Cfa-020591	Canis familiaris	94.67	0.00e+00	1042.00
IUUC-Cpo-021480	Cavia porcellus	97.26	0.00e+00	970.00
IUUC-Csa-024152	Chlorocebus sabaeus	96.27	0.00e+00	978.00
IUUC-Cho-024687	Choloepus hoffmanni	96.78	0.00e+00	895.00
IUUC-Csv-026184	Ciona savignyi	42.21	2.00e-87	315.00
IUUC-Cgl-026456	Colletotrichum gloeosporioides	43.18	6.00e-97	348.00
IUUC-Dre-028541	Danio rerio	83.97	0.00e+00	795.00
IUUC-Dno-029552	Dasypus novemcinctus	97.01	0.00e+00	892.00
IUUC-Dor-030989	Dipodomys ordii	73.33	0.00e+00	762.00
IUUC-Dse-031378	Dothistroma septosporum	41.96	3.00e-91	329.00
IUUC-Dme-032091	Drosophila melanogaster	54.08	3.00e-155	541.00
IUUC-Ete-032839	Echinops telfairi	87.97	0.00e+00	868.00
IUUC-Eca-034118	Equus caballus	97.06	0.00e+00	972.00
IUUC-Fca-035549	Felis catus	97.26	0.00e+00	971.00
IUUC-Fal-037065	Ficedula albicollis	93.49	0.00e+00	947.00
IUUC-Fox-037737	Fusarium oxysporum	43.03	4.00e-93	335.00
IUUC-Fso-038184	Fusarium solani	42.93	2.00e-98	353.00
IUUC-Gmo-038678	Gadus morhua	77.59	0.00e+00	781.00
IUUC-Ggr-039956	Gaeumannomyces graminis	42.39	3.00e-96	345.00
IUUC-Gga-040842	Gallus gallus	94.32	0.00e+00	953.00
IUUC-Gac-041543	Gasterosteus aculeatus	78.03	0.00e+00	775.00
IUUC-Ggo-044477	Gorilla gorilla	93.74	0.00e+00	1031.00
IUUC-Hsa-046610	Homo sapiens	93.93	0.00e+00	1031.00
IUUC-Itr-048583	Ictidomys tridecemlineatus	92.03	0.00e+00	1008.00
IUUC-Lch-050453	Latimeria chalumnae	83.30	0.00e+00	831.00
IUUC-Loc-052911	Lepisosteus oculatus	83.79	0.00e+00	835.00
IUUC-Lma-053160	Leptosphaeria maculans	43.03	6.00e-99	354.00
IUUC-Laf-053416	Loxodonta africana	96.62	0.00e+00	967.00
IUUC-Mcc-055113	Macaca mulatta	97.48	0.00e+00	976.00
IUUC-Meu-056732	Macropus eugenii	81.68	0.00e+00	753.00
IUUC-Mor-056978	Magnaporthe oryzae	39.29	5.00e-99	355.00
IUUC-Mpo-057410	Magnaporthe poae	42.89	5.00e-90	325.00
IUUC-Mla-058883	Melampsora laricipopulina	42.08	6.00e-87	314.00
IUUC-Mga-060143	Meleagris gallopavo	94.29	0.00e+00	946.00
IUUC-Mmr-061130	Microcebus murinus	93.52	0.00e+00	1019.00
IUUC-Mdo-062851	Monodelphis domestica	86.34	0.00e+00	809.00
IUUC-Mmu-063663	Mus musculus	95.78	0.00e+00	954.00
IUUC-Mpu-066179	Mustela putorius furo	96.62	0.00e+00	966.00
IUUC-Mlu-068175	Myotis lucifugus	96.47	0.00e+00	975.00
IUUC-Nfi-068476	Neosartorya fischeri	42.33	2.00e-96	346.00
IUUC-Ncr-068781	Neurospora crassa	42.64	3.00e-98	352.00
IUUC-Nle-070001	Nomascus leucogenys	93.60	0.00e+00	793.00
IUUC-Opr-070617	Ochotona princeps	97.47	0.00e+00	941.00
IUUC-Ont-072629	Oreochromis niloticus	82.24	0.00e+00	839.00
IUUC-Oan-073547	Ornithorhynchus anatinus	95.13	0.00e+00	950.00
IUUC-Ola-086558	Oryzias latipes	80.71	0.00e+00	830.00
IUUC-Oga-089145	Otolemur garnettii	97.05	0.00e+00	970.00
IUUC-Oar-089654	Ovis aries	91.83	0.00e+00	980.00
IUUC-Ptr-090763	Pan troglodytes	97.26	0.00e+00	971.00
IUUC-Pan-091885	Papio anubis	96.94	0.00e+00	930.00
IUUC-Psi-093011	Pelodiscus sinensis	92.84	0.00e+00	936.00
IUUC-Pno-094994	Phaeosphaeria nodorum	43.89	9.00e-98	350.00
IUUC-Pfo-097309	Poecilia formosa	82.24	0.00e+00	843.00
IUUC-Pab-097542	Pongo abelii	88.82	0.00e+00	866.00
IUUC-Pca-100630	Procavia capensis	83.30	0.00e+00	783.00
IUUC-Pva-102659	Pteropus vampyrus	72.88	0.00e+00	768.00
IUUC-Pgr-103354	Puccinia graminis	41.15	4.00e-90	325.00
IUUC-Ptt-103735	Puccinia triticina	34.57	2.00e-69	256.00
IUUC-Pte-104194	Pyrenophora teres	42.64	2.00e-98	353.00
IUUC-Pyt-104437	Pyrenophora triticirepentis	42.64	2.00e-98	352.00
IUUC-Rno-105330	Rattus norvegicus	96.20	0.00e+00	960.00
IUUC-Sha-106695	Sarcophilus harrisii	93.17	0.00e+00	767.00
IUUC-Sja-107992	Schizosaccharomyces japonicus	41.46	2.00e-97	349.00
IUUC-Spo-108364	Schizosaccharomyces pombe	40.12	1.00e-99	357.00
IUUC-Ssc-115348	Sus scrofa	91.63	0.00e+00	997.00
IUUC-Tgu-116597	Taeniopygia guttata	94.53	0.00e+00	948.00
IUUC-Tru-118425	Takifugu rubripes	80.67	0.00e+00	823.00
IUUC-Tsy-119223	Tarsius syrichta	86.21	0.00e+00	756.00
IUUC-Tni-120610	Tetraodon nigroviridis	80.38	0.00e+00	818.00
IUUC-Tre-122159	Trichoderma reesei	41.26	1.00e-93	337.00
IUUC-Tvi-122480	Trichoderma virens	41.75	6.00e-95	341.00
IUUC-Tbe-127679	Tupaia belangeri	86.44	0.00e+00	637.00
IUUC-Ttr-129226	Tursiops truncatus	86.67	0.00e+00	832.00
IUUC-Vda-129792	Verticillium dahliae	42.14	1.00e-94	340.00
IUUC-Vpa-130339	Vicugna pacos	97.60	0.00e+00	697.00
IUUC-Xtr-132873	Xenopus tropicalis	74.53	0.00e+00	748.00
IUUC-Xma-134047	Xiphophorus maculatus	82.49	0.00e+00	845.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence