iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117536

Ensembl Protein ID

ENSTRUP00000017915.1

UniProt Accession

H2SZS7; H2SZS7_TAKRU

Protein Name

Phosphoinositide phospholipase C

Gene Name

plcg2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000007265.1	ENSTRUT00000017988.1	ENSTRUP00000017914.1
ENSTRUG00000007265.1	ENSTRUT00000017989.1	ENSTRUP00000017915.1
ENSTRUG00000007265.1	ENSTRUT00000017990.1	ENSTRUP00000017916.1
ENSTRUG00000007265.1	ENSTRUT00000017991.1	ENSTRUP00000017917.1
ENSTRUG00000007265.1	ENSTRUT00000017992.1	ENSTRUP00000017918.1
ENSTRUG00000007265.1	ENSTRUT00000017993.1	ENSTRUP00000017919.1
ENSTRUG00000007265.1	ENSTRUT00000017994.1	ENSTRUP00000017920.1
ENSTRUG00000007265.1	ENSTRUT00000017995.1	ENSTRUP00000017921.1
ENSTRUG00000007265.1	ENSTRUT00000017996.1	ENSTRUP00000017922.1
ENSTRUG00000007265.1	ENSTRUT00000017997.1	ENSTRUP00000017923.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.60e-10	40.5	782	840

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           sk +v++ly+y+a+  deL++ kG  ++ i   +++++W+kg     + + +fP+n ve+++
   Q: 782  SKSVVRALYSYQAARPDELSFSKGALIYNI--SKENGDWWKGD-YGGKVQHFFPANHVEEVS 840
           6889**************************..788999****3.5555678********996 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

WSLVFSFLFI NPAVEMAERG QQGEMTDYKK ILIKRDLEMG AVMTVFRQKA ERLTVQVIME 60
TRQVAWTRTV DKTDGVLDLF EIREIRPGRN SKDFERFKDG KDKHDDNACF TIFYGSQFVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAAACAGTC TCCCATACAT CATCTATCTC TCCCAAACAC ACCAACACAC ACAGCTACGC 60
ACACACATAA TTGAGTAAGC CTTGTCCTAA TCATCTTGGT CATTGGTATT TTCATTCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0732--Signal
KW-0807--Transducer

Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR011993--PH_dom-like
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR028381--PLC-gamma2
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3

Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0035556--P:intracellular signal transduction
GO:0009395--P:phospholipid catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003345	Anas platyrhynchos	59.49	0.00e+00	1410.00
IUUC-Aca-004266	Anolis carolinensis	57.34	0.00e+00	1447.00
IUUC-Ame-011540	Astyanax mexicanus	67.08	0.00e+00	1644.00
IUUC-Bta-013196	Bos taurus	57.39	0.00e+00	1411.00
IUUC-Cpo-021890	Cavia porcellus	56.93	0.00e+00	1461.00
IUUC-Csa-024233	Chlorocebus sabaeus	56.48	0.00e+00	1451.00
IUUC-Dre-028650	Danio rerio	66.80	0.00e+00	1645.00
IUUC-Dno-028871	Dasypus novemcinctus	57.04	0.00e+00	1423.00
IUUC-Eca-033458	Equus caballus	57.11	0.00e+00	1457.00
IUUC-Eeu-035329	Erinaceus europaeus	54.74	0.00e+00	1383.00
IUUC-Fal-037390	Ficedula albicollis	58.17	0.00e+00	1474.00
IUUC-Gga-040918	Gallus gallus	58.42	0.00e+00	1469.00
IUUC-Ggo-045625	Gorilla gorilla	55.96	0.00e+00	1422.00
IUUC-Hsa-046129	Homo sapiens	56.99	0.00e+00	1461.00
IUUC-Loc-052025	Lepisosteus oculatus	67.24	0.00e+00	1677.00
IUUC-Mcc-054831	Macaca mulatta	57.52	0.00e+00	1437.00
IUUC-Mga-059368	Meleagris gallopavo	58.50	0.00e+00	1449.00
IUUC-Mvi-060364	Microbotryum violaceum	43.86	9.00e-11	60.80
IUUC-Mmr-060898	Microcebus murinus	54.97	0.00e+00	1316.00
IUUC-Mmu-064334	Mus musculus	56.64	0.00e+00	1446.00
IUUC-Mlu-067230	Myotis lucifugus	57.22	0.00e+00	1459.00
IUUC-Nle-069318	Nomascus leucogenys	53.32	0.00e+00	1323.00
IUUC-Opr-070718	Ochotona princeps	53.46	0.00e+00	696.00
IUUC-Ocu-073814	Oryctolagus cuniculus	57.27	0.00e+00	1455.00
IUUC-Ola-086501	Oryzias latipes	75.28	0.00e+00	1949.00
IUUC-Oar-089556	Ovis aries	56.45	0.00e+00	1400.00
IUUC-Ptr-091001	Pan troglodytes	56.91	0.00e+00	1458.00
IUUC-Pan-092744	Papio anubis	56.56	0.00e+00	1447.00
IUUC-Psi-093987	Pelodiscus sinensis	57.47	0.00e+00	1466.00
IUUC-Pfo-096249	Poecilia formosa	77.99	0.00e+00	2001.00
IUUC-Pab-098268	Pongo abelii	56.00	0.00e+00	1426.00
IUUC-Pva-102939	Pteropus vampyrus	56.36	0.00e+00	1360.00
IUUC-Ssc-115308	Sus scrofa	55.30	0.00e+00	1300.00
IUUC-Tgu-116811	Taeniopygia guttata	58.01	0.00e+00	1466.00
IUUC-Tsy-119139	Tarsius syrichta	54.90	6.00e-174	605.00
IUUC-Ttr-128392	Tursiops truncatus	54.39	0.00e+00	1366.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence