iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-021241

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03010573

Gene Name

LOC611374

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000029429.1	ENSCAFT00000038090.2	ENSCAFP00000040809.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.80e-76	255.6	81	375

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl+N+gNtCY+N++LQcL+ +++l++++l++++ ++ +     ++ ++l++lq  ++ +         p ++l+ l  +   f+  +q+
   Q: 81   GLQNMGNTCYVNATLQCLTYTEPLASYMLSQQHGTTCR----RQTSCMLCTLQAHLTRV------LCHPGRVLRPLPLLLAAFHRHKQE 159
           9*****************************33333322....35678888888888888......455666666666666779999*** PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+E+l+f+ld++++++          +        +d+ ++ +  + ++li++lF+g ++sqi+cl+c+ +ss+ ep ld+sl++ + 
   Q: 160  DAHEYLMFILDAMQQAC----------L-------PEDKLSDPERPQDSTLIQQLFEGYWRSQIQCLHCQGISSTLEPYLDISLDIGDA 231
           *****************..........2.......22334567888999**************************************** PP
   S: 180  eetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctsp 268
           +     s++++Le+ +k+e legen+y+c+kc +k+ a+k l+l++ P+vLil L Rf    +    +k++k+v++p++Ld++++++++
   Q: 232  H-----SVSQALEQLVKPELLEGENAYHCRKCLEKVPASKVLTLHTSPKVLILVLRRF----SDLTGNKMTKEVQYPERLDMQHYLSEQ 311
           *.....9***************************************************....346778********************6 PP
   S: 269  eekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
             +   +  Y L+av+vH G s++sGHY+++vk  +g+W+++dD kV++++ +  l+   + aYvlfY++
   Q: 312  RAG---PLVYVLYAVLVHAGrSCHSGHYFCFVKAGNGQWYKMDDAKVSACDVTCALR---QPAYVLFYMQ 375
           655...9********************************************999999...9*******98 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MEAAHLHPSE EPQFSASPKP QSCWSRRGGA EVHGGPSVPE TTSPASKTLS SPTDPLAPAS 60
AGLPPTKTPL SWKSLSQVGA GLQNMGNTCY VNATLQCLTY TEPLASYMLS QQHGTTCRRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCTG CCCACCTCCA CCCCTCAGAG GAGCCTCAGT TCAGCGCCTC TCCCAAACCC 60
CAGTCATGCT GGTCAAGGAG AGGCGGTGCT GAAGTCCACG GAGGACCCTC TGTGCCCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006861--HABP4_PAIRBP1-bd
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF04774--HABP4_PAI-RBP1
PF00443--UCH

SMART

SM01233--HABP4_PAI-RBP1

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002148	Ailuropoda melanoleuca	69.49	0.00e+00	679.00
IUUC-Ggo-044751	Gorilla gorilla	54.14	1.00e-141	496.00
IUUC-Hsa-046171	Homo sapiens	53.95	2.00e-142	499.00
IUUC-Ptr-091297	Pan troglodytes	53.57	1.00e-140	493.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence