iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023524

Ensembl Protein ID

ENSCSAP00000009911.1

UniProt Accession

A0A0D9RMS2; A0A0D9RMS2_CHLSB

Genbank Protein ID

ENSCSAP00000009911

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01137822

Gene Name

PAFAH1B1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000013754.1	ENSCSAT00000011851.1	ENSCSAP00000009911.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-59	194.5	271	309
UBD/Beta-Prp	3.00e-94	315.5	42	345

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH ++v+++ f s+ ++++s++dD+t++vWD++  ++ k
   Q: 271  GHDNWVRGVLFhSGgKFILSCADDKTLRVWDYKNKRCMK 309
           8**********9888****************99998876 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h s++t v f+p  s+++++s+d+tikvwd++tg++ r+l+gh++ v++++f+++gk+l ++s D+tik+wd++ ++c++t++gh+++v
   Q: 42   HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLTSCSADMTIKLWDFQGFECIRTMHGHDHNV 130
           5668888********************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysl 186
            s++++p+gd+lvs+s+d+ti++w+++tg+c++ t++gh+++v++v+ ++dg l++s+s+D+tvr+W ++t+++  +l++ h++ v+++
   Q: 131  SSVAIMPNGDHLVSASRDKTIKMWEVQTGYCVK-TFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE-HEHVVECI 217
           *********************************.*********************************************9.******** PP
   S: 187  sfdsng....................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgd 255
           s+ +++                    ++l+sgs+d+t+k+wd++tg c++tl gh+++v+ v f++ +++++s+++D+++r+Wd++++ 
   Q: 218  SWAPESsyssiseatgsetkksgkpgPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKR 306
           ***************************************************************************************** PP
   S: 256  llktlqlhnssvisvavlsfgdnvlvlgsedskvniwklk 295
           ++ktl+ h++ v+s ++ + + +++v+gs d++v++w+++
   Q: 307  CMKTLNAHEHFVTSLDF-HKTAPYVVTGSVDQTVKVWECR 345
           *****************.99*****************985 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MELESKLNEA KEEFTSGGPL GQKRDPKEWI PRPPEKYALS GHRSPVTRVI FHPVFSVMVS 60
ASEDATIKVW DYETGDFERT LKGHTDSVQD ISFDHSGKLL TSCSADMTIK LWDFQGFECI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATGAGTAA TCTTTGGCTT GAGGATCATA GTTAAGCCAT TCTTAAAAGG TTCTAACTTT 60
ATTTTCTCTA GAATGAAGAA TTAGATAAAA AGTATGCTGG TCTTTTGGAA AAAAAATGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR017252--Dynein_regulator_LIS1
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000235--C:astral microtubule
GO:1904115--C:axon cytoplasm
GO:0005938--C:cell cortex
GO:0031252--C:cell leading edge
GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0000776--C:kinetochore
GO:0005875--C:microtubule associated complex
GO:0031514--C:motile cilium
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0032420--C:stereocilium
GO:0001675--P:acrosome assembly
GO:0030036--P:actin cytoskeleton organization
GO:0008344--P:adult locomotory behavior
GO:0001667--P:ameboidal-type cell migration
GO:0060117--P:auditory receptor cell development
GO:0048854--P:brain morphogenesis
GO:0051301--P:cell division
GO:0007268--P:chemical synaptic transmission
GO:0090102--P:cochlea development
GO:0021540--P:corpus callosum morphogenesis
GO:0043622--P:cortical microtubule organization
GO:0000132--P:establishment of mitotic spindle orientation
GO:0042249--P:establishment of planar polarity of embryonic epithelium
GO:0021766--P:hippocampus development
GO:0021819--P:layer formation in cerebral cortex
GO:0007611--P:learning or memory
GO:0051661--P:maintenance of centrosome location
GO:0090176--P:microtubule cytoskeleton organization involved in establishment of planar polarity
GO:0031023--P:microtubule organizing center organization
GO:0007067--P:mitotic nuclear division
GO:0046329--P:negative regulation of JNK cascade
GO:0007405--P:neuroblast proliferation
GO:0050885--P:neuromuscular process controlling balance
GO:0001764--P:neuron migration
GO:0051081--P:nuclear envelope disassembly
GO:0036035--P:osteoclast development
GO:0001961--P:positive regulation of cytokine-mediated signaling pathway
GO:0061003--P:positive regulation of dendritic spine morphogenesis
GO:0040019--P:positive regulation of embryonic development
GO:0009306--P:protein secretion
GO:0043087--P:regulation of GTPase activity
GO:0070507--P:regulation of microtubule cytoskeleton organization
GO:0008090--P:retrograde axonal transport
GO:0019226--P:transmission of nerve impulse
GO:0047496--P:vesicle transport along microtubule

KEGG

csab:103242137

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001589	Ailuropoda melanoleuca	99.42	0.00e+00	720.00
IUUC-Apl-004024	Anas platyrhynchos	98.26	0.00e+00	717.00
IUUC-Aca-004564	Anolis carolinensis	97.97	0.00e+00	711.00
IUUC-Acl-008360	Aspergillus clavatus	47.04	6.00e-88	317.00
IUUC-Afl-008502	Aspergillus flavus	46.99	6.00e-83	301.00
IUUC-Afu-008848	Aspergillus fumigatus	47.81	1.00e-89	323.00
IUUC-Ani-009173	Aspergillus nidulans	44.61	3.00e-78	285.00
IUUC-Ang-009873	Aspergillus niger	44.98	3.00e-78	285.00
IUUC-Aor-009973	Aspergillus oryzae	47.19	3.00e-81	295.00
IUUC-Ate-010523	Aspergillus terreus	42.90	4.00e-76	278.00
IUUC-Ame-010969	Astyanax mexicanus	93.62	0.00e+00	687.00
IUUC-Bgr-011972	Blumeria graminis	49.29	2.00e-89	323.00
IUUC-Bta-013106	Bos taurus	99.42	0.00e+00	721.00
IUUC-Bci-013615	Botrytis cinerea	44.25	1.00e-81	296.00
IUUC-Cel-018459	Caenorhabditis elegans	57.68	2.00e-125	442.00
IUUC-Cja-018755	Callithrix jacchus	99.42	0.00e+00	721.00
IUUC-Cfa-020749	Canis familiaris	99.42	0.00e+00	721.00
IUUC-Cpo-022371	Cavia porcellus	99.42	0.00e+00	721.00
IUUC-Cho-024764	Choloepus hoffmanni	87.83	6.00e-180	623.00
IUUC-Cin-025753	Ciona intestinalis	71.01	1.00e-152	532.00
IUUC-Csv-025817	Ciona savignyi	69.28	5.00e-155	540.00
IUUC-Cgl-026529	Colletotrichum gloeosporioides	47.61	4.00e-84	305.00
IUUC-Cne-027087	Cryptococcus neoformans	51.35	1.00e-102	366.00
IUUC-Dre-028314	Danio rerio	92.75	0.00e+00	686.00
IUUC-Dno-029050	Dasypus novemcinctus	99.13	0.00e+00	720.00
IUUC-Dor-030222	Dipodomys ordii	89.57	0.00e+00	639.00
IUUC-Dse-031164	Dothistroma septosporum	43.64	2.00e-84	305.00
IUUC-Dme-031745	Drosophila melanogaster	70.30	4.00e-144	504.00
IUUC-Ete-032508	Echinops telfairi	98.92	6.00e-167	580.00
IUUC-Eca-034288	Equus caballus	99.42	0.00e+00	720.00
IUUC-Eeu-034984	Erinaceus europaeus	89.28	0.00e+00	635.00
IUUC-Fca-036498	Felis catus	99.42	0.00e+00	721.00
IUUC-Fal-036920	Ficedula albicollis	98.26	0.00e+00	717.00
IUUC-Fox-037996	Fusarium oxysporum	46.88	1.00e-87	317.00
IUUC-Fso-038160	Fusarium solani	45.14	5.00e-85	308.00
IUUC-Gmo-038983	Gadus morhua	92.75	0.00e+00	678.00
IUUC-Ggr-040051	Gaeumannomyces graminis	44.57	3.00e-83	302.00
IUUC-Gga-040623	Gallus gallus	98.26	0.00e+00	717.00
IUUC-Gac-041613	Gasterosteus aculeatus	91.59	0.00e+00	677.00
IUUC-Ggo-045410	Gorilla gorilla	90.14	0.00e+00	644.00
IUUC-Hsa-046358	Homo sapiens	99.42	0.00e+00	721.00
IUUC-Itr-047890	Ictidomys tridecemlineatus	99.42	0.00e+00	721.00
IUUC-Lch-049936	Latimeria chalumnae	95.65	0.00e+00	697.00
IUUC-Loc-052476	Lepisosteus oculatus	94.78	0.00e+00	691.00
IUUC-Lma-053170	Leptosphaeria maculans	47.03	8.00e-87	314.00
IUUC-Laf-053713	Loxodonta africana	99.13	0.00e+00	720.00
IUUC-Mcc-054628	Macaca mulatta	100.00	0.00e+00	723.00
IUUC-Meu-055927	Macropus eugenii	85.92	1.00e-138	485.00
IUUC-Mor-056962	Magnaporthe oryzae	45.14	3.00e-83	302.00
IUUC-Mpo-057583	Magnaporthe poae	44.79	2.00e-79	290.00
IUUC-Mla-058819	Melampsora laricipopulina	47.76	3.00e-98	352.00
IUUC-Mga-059945	Meleagris gallopavo	97.97	0.00e+00	716.00
IUUC-Mvi-060403	Microbotryum violaceum	48.81	5.00e-107	381.00
IUUC-Mmr-061289	Microcebus murinus	99.42	0.00e+00	720.00
IUUC-Mdo-061912	Monodelphis domestica	98.55	0.00e+00	714.00
IUUC-Mmu-063253	Mus musculus	99.42	0.00e+00	721.00
IUUC-Mpu-066638	Mustela putorius furo	99.42	0.00e+00	721.00
IUUC-Mlu-067267	Myotis lucifugus	99.13	0.00e+00	718.00
IUUC-Nfi-068571	Neosartorya fischeri	48.90	2.00e-86	312.00
IUUC-Ncr-068895	Neurospora crassa	48.82	1.00e-90	326.00
IUUC-Nle-069087	Nomascus leucogenys	98.89	4.00e-162	563.00
IUUC-Opr-070579	Ochotona princeps	99.13	0.00e+00	720.00
IUUC-Ont-072432	Oreochromis niloticus	93.62	0.00e+00	690.00
IUUC-Oan-073072	Ornithorhynchus anatinus	99.42	0.00e+00	721.00
IUUC-Ocu-074180	Oryctolagus cuniculus	99.13	0.00e+00	720.00
IUUC-Ola-086772	Oryzias latipes	93.04	0.00e+00	681.00
IUUC-Oga-088219	Otolemur garnettii	99.42	0.00e+00	722.00
IUUC-Oar-090394	Ovis aries	99.42	0.00e+00	721.00
IUUC-Ptr-091517	Pan troglodytes	99.42	0.00e+00	721.00
IUUC-Pan-092421	Papio anubis	100.00	0.00e+00	723.00
IUUC-Psi-093370	Pelodiscus sinensis	98.55	0.00e+00	718.00
IUUC-Pma-094319	Petromyzon marinus	89.05	0.00e+00	635.00
IUUC-Pno-094815	Phaeosphaeria nodorum	47.59	1.00e-87	317.00
IUUC-Pfo-097089	Poecilia formosa	92.46	0.00e+00	682.00
IUUC-Pab-098421	Pongo abelii	99.42	0.00e+00	721.00
IUUC-Pca-100120	Procavia capensis	72.17	3.00e-130	458.00
IUUC-Pva-102960	Pteropus vampyrus	99.13	0.00e+00	717.00
IUUC-Pgr-103538	Puccinia graminis	45.93	7.00e-97	347.00
IUUC-Pte-104261	Pyrenophora teres	47.31	6.00e-87	314.00
IUUC-Pyt-104780	Pyrenophora triticirepentis	47.59	2.00e-87	315.00
IUUC-Rno-105123	Rattus norvegicus	99.42	0.00e+00	721.00
IUUC-Sha-107010	Sarcophilus harrisii	98.26	0.00e+00	712.00
IUUC-Sja-107899	Schizosaccharomyces japonicus	31.15	4.00e-51	195.00
IUUC-Ssl-108571	Sclerotinia sclerotiorum	44.54	5.00e-82	298.00
IUUC-Sar-113309	Sorex araneus	99.42	0.00e+00	720.00
IUUC-Sre-115003	Sporisorium reilianum	49.06	9.00e-104	370.00
IUUC-Ssc-116148	Sus scrofa	99.42	0.00e+00	721.00
IUUC-Tgu-117299	Taeniopygia guttata	98.26	0.00e+00	716.00
IUUC-Tru-118179	Takifugu rubripes	90.72	0.00e+00	675.00
IUUC-Tsy-119493	Tarsius syrichta	97.68	0.00e+00	704.00
IUUC-Tni-120355	Tetraodon nigroviridis	91.88	0.00e+00	650.00
IUUC-Tre-121977	Trichoderma reesei	44.16	4.00e-86	311.00
IUUC-Tvi-122661	Trichoderma virens	43.69	4.00e-85	308.00
IUUC-Tme-127031	Tuber melanosporum	51.29	8.00e-89	320.00
IUUC-Tbe-127492	Tupaia belangeri	82.69	2.00e-114	405.00
IUUC-Ttr-128929	Tursiops truncatus	99.13	0.00e+00	719.00
IUUC-Uma-129347	Ustilago maydis	46.92	1.00e-101	363.00
IUUC-Vda-129837	Verticillium dahliae	45.43	1.00e-82	300.00
IUUC-Vpa-130532	Vicugna pacos	82.24	6.00e-153	533.00
IUUC-Xtr-131985	Xenopus tropicalis	96.52	0.00e+00	707.00
IUUC-Xma-133314	Xiphophorus maculatus	93.04	0.00e+00	685.00
IUUC-Yli-134403	Yarrowia lipolytica	39.26	9.00e-67	247.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence