iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089263

Ensembl Protein ID

ENSOARP00000010272.1

UniProt Accession

W5PIK3; W5PIK3_SHEEP

Genbank Protein ID

ENSOARP00000010272

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01117864

Gene Name

USP26

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000009577.1	ENSOART00000010424.1	ENSOARP00000010272.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.10e-74	249.4	283	872

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklf..eelwkskkkavsprellkalkkeaeefsgy 87
           +G+ NlgNtCYmN+vLQ+L+ ip++ ++ll+   ++ ++   k p  +l+++l++lf  + +++ + k+    +++k+++++ae f  +
   Q: 283  QGFPNLGNTCYMNAVLQSLFLIPSFGDDLLN---RTYPWC--KIPPDALSMCLAQLFvlKDIYNINIKKRLLANIKKTISAVAEIFADN 366
           59*****************************...666665..46888999999999822455699999999****************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           +q+Da+Efl + l+q++e+++k ++  k++ e++++++l+     +  k+   +++ ++F+++l  +i+c++c++   ++e  ++l+++
   Q: 367  AQNDAHEFLGHYLSQMKENMEKLNKVWKTKIESKEENSLQPFfVGSAAKEALLCPVITNFEFELLCSITCKACGHAVLKTEVSNYLPIN 455
           ********************883333334444444445555426677777888************************************ PP
   S: 176  vpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
           +p+ ++  + s+q++L+ f+++e+le    y ce+ck+k+ +  k k+++lP+vLi+hLkR++f e   s +k +++v + ++L++s++
   Q: 456  LPQGRQALPFSIQSSLDLFFETENLE----YTCEQCKHKK-SHVKYKFSRLPRVLIVHLKRYNFIEF-RSLKKDDQEVIISKNLKISSH 538
           *************************9....*******998.56677******************998.5567***************** PP
   S: 265  cts...................................................................................... 267
           c++                                                                                      
   Q: 539  CNEntrppfplnkkahlinlkflkifrnlnseaiskltpsakmtsefmkslpsyivpddepepekdhvhheglreeekqkdlgkysilk 627
           **************************************999999999999999999999999999999999999888888888888888 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 628  ildsalansqdglivarellavalmmnmedcsfslreitisdpdvcqkvfenpklkederinmfadfeavakitkdkdenakisedvsp 716
           88888888888888888888888888888888888888888888888888888888888888888888888887777777777777777 PP
   S: 268  ............................peekqke...................................................... 274
                                       p     +                                                      
   Q: 717  vaeqtqnkermktyeqalwlallqsfpkP-----Ktqkkkcteklkrpkesgvqgtkvnspgasgrnkksrkksclgtekteaasnepk 800
           77666666666666666666666666551.....0444555666666666666666666677777777777777788888888888888 PP
   S: 275  .......kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
                  ++ Y+Li+v++H G sl+sGHY++++++  ++ W++++D +Vt ++e+++++ + s++Yv+fY++
   Q: 801  geaemedRQAYRLIGVLSHLGkSLNSGHYISDAYDFVRQeWFTYNDLQVTNIEEATMQKARLSSGYVFFYMH 872
           8888888****************************77777*******************999********98 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MVPVAAHGFV QLWNKKNGMS KSKEAVVEVS GKKKKTKLVI CFCNGESRTF ELHNNIKNVV 60
VRSYGEKVNH LHLTFQNNSF FFMEKISSKD VKKLKAFLDG VHQNHLPPPI KPDVDSSAFA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTTCCTG TAGCAGCACA TGGTTTTGTC CAATTATGGA ACAAGAAGAA TGGGATGTCT 60
AAGTCGAAGG AAGCAGTCGT CGAAGTATCG GGAAAAAAGA AGAAAACTAA ATTGGTGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002281	Ailuropoda melanoleuca	55.51	0.00e+00	926.00
IUUC-Bta-012832	Bos taurus	89.11	0.00e+00	1538.00
IUUC-Cja-019801	Callithrix jacchus	45.29	0.00e+00	692.00
IUUC-Cfa-020088	Canis familiaris	54.85	0.00e+00	909.00
IUUC-Cpo-022049	Cavia porcellus	37.80	1.00e-156	546.00
IUUC-Csa-023990	Chlorocebus sabaeus	48.03	0.00e+00	724.00
IUUC-Dor-030370	Dipodomys ordii	37.91	6.00e-153	534.00
IUUC-Ete-033046	Echinops telfairi	47.58	4.00e-84	305.00
IUUC-Eca-034060	Equus caballus	54.73	0.00e+00	853.00
IUUC-Fca-035628	Felis catus	53.08	0.00e+00	864.00
IUUC-Ggo-045311	Gorilla gorilla	47.30	0.00e+00	716.00
IUUC-Hsa-046292	Homo sapiens	47.54	0.00e+00	707.00
IUUC-Itr-047983	Ictidomys tridecemlineatus	46.06	0.00e+00	717.00
IUUC-Laf-054311	Loxodonta africana	44.21	0.00e+00	648.00
IUUC-Mmr-061542	Microcebus murinus	51.78	0.00e+00	846.00
IUUC-Mmu-063365	Mus musculus	38.22	5.00e-113	402.00
IUUC-Mpu-066846	Mustela putorius furo	53.48	0.00e+00	897.00
IUUC-Mlu-068224	Myotis lucifugus	51.89	0.00e+00	837.00
IUUC-Ocu-073860	Oryctolagus cuniculus	46.56	0.00e+00	698.00
IUUC-Oga-088020	Otolemur garnettii	42.74	0.00e+00	634.00
IUUC-Pan-092928	Papio anubis	47.26	0.00e+00	697.00
IUUC-Pab-098555	Pongo abelii	47.59	0.00e+00	738.00
IUUC-Sar-113624	Sorex araneus	40.07	1.00e-152	533.00
IUUC-Ssc-116225	Sus scrofa	58.97	0.00e+00	1023.00
IUUC-Tbe-127615	Tupaia belangeri	49.78	5.00e-100	359.00
IUUC-Ttr-129071	Tursiops truncatus	49.94	0.00e+00	830.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence