iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067987

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02033443

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000027650.1	ENSMLUT00000012169.2	ENSMLUP00000021067.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.80e-43	147.0	6	141

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl+kel+e++k  +++++  +vde++l +w+ li+ p++ pY++g+F++ei+fp +YPfkPP+++f tki+hPn++e+G+vCl ++ ++
   Q: 6    RLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEISFPAEYPFKPPTITFKTKIYHPNIDEKGQVCLPVI-SA 92
           9**********************************.**************************************************.5* PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           e+W+pa++  +v+ s+++l+++p++e+pl+++ ae+++k+r+++ k+++
   Q: 93   ENWKPATKTDQVIQSLIALVNDPQTEHPLRADLAEEYSKDRKKFCKNAE 141
           *********************************************9986 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAASRRLMKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEISFPAE 60
YPFKPPTITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQVIQSLIA LVNDPQTEHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGCCA GCAGGAGGCT GATGAAGGAG CTTGAAGAAA TCCGCAAATG TGGAATGAAA 60
AACTTCCGTA ACATCCAGGT TGATGAAGCT AATTTACTGA CTTGGCAAGG GCTTATTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003723--F:RNA binding
GO:0003713--F:transcription coactivator activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0044770--P:cell cycle phase transition
GO:0008283--P:cell proliferation
GO:0071385--P:cellular response to glucocorticoid stimulus
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018332	Caenorhabditis elegans	57.89	5.00e-57	213.00
IUUC-Cja-019062	Callithrix jacchus	98.05	5.00e-77	279.00
IUUC-Cfa-020027	Canis familiaris	98.05	5.00e-77	279.00
IUUC-Cpo-022341	Cavia porcellus	98.05	5.00e-77	279.00
IUUC-Cho-024916	Choloepus hoffmanni	91.18	2.00e-42	163.00
IUUC-Cin-025130	Ciona intestinalis	64.94	6.00e-46	176.00
IUUC-Csv-026183	Ciona savignyi	64.24	8.00e-47	179.00
IUUC-Dre-027710	Danio rerio	93.51	5.00e-73	266.00
IUUC-Dor-031017	Dipodomys ordii	93.51	4.00e-71	259.00
IUUC-Dme-031814	Drosophila melanogaster	72.08	6.00e-67	245.00
IUUC-Ete-032754	Echinops telfairi	98.05	5.00e-77	279.00
IUUC-Eca-034056	Equus caballus	94.81	1.00e-74	271.00
IUUC-Eeu-034942	Erinaceus europaeus	96.75	4.00e-76	276.00
IUUC-Fca-036173	Felis catus	98.05	5.00e-77	279.00
IUUC-Gga-041039	Gallus gallus	98.05	5.00e-77	279.00
IUUC-Gac-041571	Gasterosteus aculeatus	76.16	6.00e-56	209.00
IUUC-Ggo-044482	Gorilla gorilla	97.96	1.00e-72	265.00
IUUC-Hsa-046287	Homo sapiens	98.05	5.00e-77	279.00
IUUC-Loc-052000	Lepisosteus oculatus	91.67	6.00e-71	259.00
IUUC-Mcc-054978	Macaca mulatta	96.75	2.00e-86	310.00
IUUC-Meu-056738	Macropus eugenii	98.06	2.00e-47	179.00
IUUC-Mga-060134	Meleagris gallopavo	95.39	4.00e-72	263.00
IUUC-Mvi-060255	Microbotryum violaceum	45.27	6.00e-35	140.00
IUUC-Mmr-060627	Microcebus murinus	94.16	3.00e-82	296.00
IUUC-Mdo-062043	Monodelphis domestica	80.75	5.00e-72	263.00
IUUC-Mmu-063615	Mus musculus	98.05	5.00e-77	279.00
IUUC-Nle-069967	Nomascus leucogenys	96.10	1.00e-85	308.00
IUUC-Opr-070315	Ochotona princeps	98.05	5.00e-77	279.00
IUUC-Ont-072036	Oreochromis niloticus	91.56	4.00e-71	259.00
IUUC-Oga-088085	Otolemur garnettii	92.21	6.00e-82	295.00
IUUC-Ptr-090890	Pan troglodytes	97.40	2.00e-86	310.00
IUUC-Pan-092445	Papio anubis	97.96	1.00e-72	265.00
IUUC-Pma-094445	Petromyzon marinus	77.70	2.00e-53	201.00
IUUC-Pfo-096258	Poecilia formosa	91.56	1.00e-70	258.00
IUUC-Pab-097654	Pongo abelii	98.05	5.00e-77	279.00
IUUC-Pca-100712	Procavia capensis	77.92	3.00e-55	206.00
IUUC-Ssc-115442	Sus scrofa	98.05	5.00e-77	279.00
IUUC-Tru-117653	Takifugu rubripes	91.56	2.00e-71	260.00
IUUC-Tsy-119345	Tarsius syrichta	77.27	6.00e-53	199.00
IUUC-Tni-119709	Tetraodon nigroviridis	91.56	2.00e-71	260.00
IUUC-Tbe-127451	Tupaia belangeri	92.21	1.00e-81	295.00
IUUC-Ttr-128840	Tursiops truncatus	98.05	5.00e-77	279.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence