iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-061954

Ensembl Protein ID

ENSMODP00000009135.2

UniProt Accession

F7ADB3; F7ADB3_MONDO

Protein Name

Uncharacterized protein

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000007365.2	ENSMODT00000009316.2	ENSMODP00000009135.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	88.39	0.00e+00	782.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MVDTESQICP LSPLDDDDLE SPLSEEFLQE MGSIQDISQS IGDDSSGAFT FADYHCLGSG 60
PGSDGSIITD TLSPASSPSS VNYTPVVGSA EDSATTTLNI ECRICGDKAS GYHYGVHACE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTAAAGACC TATAAAGGGT CCAGCATCAC TTTGCCAAGA TGGTAGACAC CGAGAGCCAG 60
ATCTGCCCCC TTTCCCCACT TGATGATGAT GACCTGGAAA GTCCACTTTC TGAAGAGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	89.96	0.00e+00	844.00
IUUC-Apl-003330	Anas platyrhynchos	86.67	0.00e+00	791.00
IUUC-Aca-004598	Anolis carolinensis	85.87	0.00e+00	786.00
IUUC-Acl-008339	Aspergillus clavatus	45.45	2.10e-01	28.90
IUUC-Ame-011508	Astyanax mexicanus	71.46	0.00e+00	674.00
IUUC-Bta-012621	Bos taurus	89.25	0.00e+00	827.00
IUUC-Cja-019688	Callithrix jacchus	87.74	0.00e+00	818.00
IUUC-Cfa-020859	Canis familiaris	90.58	0.00e+00	847.00
IUUC-Cpo-021607	Cavia porcellus	81.25	0.00e+00	766.00
IUUC-Csa-023313	Chlorocebus sabaeus	87.74	0.00e+00	810.00
IUUC-Cho-024741	Choloepus hoffmanni	78.06	0.00e+00	691.00
IUUC-Dre-027446	Danio rerio	70.17	0.00e+00	657.00
IUUC-Dno-029173	Dasypus novemcinctus	86.45	0.00e+00	796.00
IUUC-Dor-030581	Dipodomys ordii	86.74	0.00e+00	752.00
IUUC-Dme-031794	Drosophila melanogaster	33.83	3.00e-56	214.00
IUUC-Ete-032330	Echinops telfairi	87.67	0.00e+00	807.00
IUUC-Eca-033712	Equus caballus	87.96	0.00e+00	811.00
IUUC-Fca-036555	Felis catus	90.40	0.00e+00	844.00
IUUC-Fal-036677	Ficedula albicollis	86.77	0.00e+00	790.00
IUUC-Gmo-039240	Gadus morhua	78.71	2.00e-176	611.00
IUUC-Gga-040473	Gallus gallus	87.22	0.00e+00	795.00
IUUC-Gac-041872	Gasterosteus aculeatus	70.36	0.00e+00	677.00
IUUC-Ggo-045226	Gorilla gorilla	88.39	0.00e+00	818.00
IUUC-Hsa-046893	Homo sapiens	88.39	0.00e+00	818.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	86.45	0.00e+00	801.00
IUUC-Lch-050116	Latimeria chalumnae	77.63	0.00e+00	728.00
IUUC-Loc-052131	Lepisosteus oculatus	80.05	0.00e+00	656.00
IUUC-Laf-054323	Loxodonta africana	88.17	0.00e+00	821.00
IUUC-Mcc-054841	Macaca mulatta	91.03	0.00e+00	820.00
IUUC-Meu-056833	Macropus eugenii	82.15	0.00e+00	729.00
IUUC-Mga-059995	Meleagris gallopavo	77.78	0.00e+00	692.00
IUUC-Mmu-064295	Mus musculus	84.52	0.00e+00	764.00
IUUC-Mpu-066216	Mustela putorius furo	91.03	0.00e+00	855.00
IUUC-Nle-069970	Nomascus leucogenys	90.81	0.00e+00	816.00
IUUC-Ont-071594	Oreochromis niloticus	71.22	0.00e+00	669.00
IUUC-Oan-073501	Ornithorhynchus anatinus	90.44	0.00e+00	719.00
IUUC-Ocu-074634	Oryctolagus cuniculus	79.63	0.00e+00	761.00
IUUC-Oni-082926	Oryza nivara	30.19	2.80e-02	29.60
IUUC-Ola-086585	Oryzias latipes	76.74	1.00e-175	608.00
IUUC-Oga-088738	Otolemur garnettii	88.60	0.00e+00	814.00
IUUC-Oar-090453	Ovis aries	89.03	0.00e+00	828.00
IUUC-Ptr-091518	Pan troglodytes	88.36	0.00e+00	819.00
IUUC-Pan-092006	Papio anubis	88.36	0.00e+00	818.00
IUUC-Psi-093352	Pelodiscus sinensis	86.00	0.00e+00	802.00
IUUC-Pfo-096060	Poecilia formosa	69.98	0.00e+00	654.00
IUUC-Pab-098602	Pongo abelii	84.96	0.00e+00	718.00
IUUC-Pva-102175	Pteropus vampyrus	82.15	0.00e+00	782.00
IUUC-Rno-105283	Rattus norvegicus	85.16	0.00e+00	769.00
IUUC-Sce-106436	Saccharomyces cerevisiae	29.03	2.50e-02	30.40
IUUC-Sha-106560	Sarcophilus harrisii	93.33	0.00e+00	861.00
IUUC-Smo-109075	Selaginella moellendorffii	28.00	5.20e-01	27.70
IUUC-Ssc-115266	Sus scrofa	91.26	0.00e+00	854.00
IUUC-Tgu-116778	Taeniopygia guttata	87.00	0.00e+00	793.00
IUUC-Tru-118436	Takifugu rubripes	70.36	0.00e+00	670.00
IUUC-Tsy-119642	Tarsius syrichta	90.35	8.00e-119	420.00
IUUC-Tni-119859	Tetraodon nigroviridis	71.22	0.00e+00	669.00
IUUC-Tvi-122624	Trichoderma virens	29.63	7.60e-01	26.60
IUUC-Tbe-127464	Tupaia belangeri	89.91	0.00e+00	833.00
IUUC-Ttr-129307	Tursiops truncatus	85.19	0.00e+00	777.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence