iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059664

Ensembl Protein ID

ENSMGAP00000014332.1

UniProt Accession

G1NLE2; G1NLE2_MELGA

Protein Name

Uncharacterized protein

Gene Name

STRAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000013559.1	ENSMGAT00000015262.1	ENSMGAP00000014332.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.90e-27	91.9	264	298
UBD/Beta-Prp	2.30e-41	141.6	46	300

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtll.vsGsdDgtikvWDlrtg 33
           gH ++++c++f +d+ l +sGs Dgt+++W ++ g
   Q: 264  GHFGPIHCVRFsPDGELyASGSEDGTLRLWQTTVG 298
           799*********997776************98765 PP

UBD/Beta-Prp

   S: 38   dvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletg 126
           + +tg+ + ++ gh+++v+  ++++d+   +t++ D t+kvwd  +g+ ++tl  h++ v s++f +++++l++G++d+ +r++dl++ 
   Q: 46   QGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELITLA-HKHIVKSVDFTQDSNYLLTGGQDKLLRIYDLSKP 133
           55678889**********************************************.********************************** PP
   S: 127  qcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng....................... 192
           +   ++ sgh++ +  + +++d++ + s ++D+tvrlWd +t++ ++ l      sv s+++ ++g                       
   Q: 134  EAEPDVVSGHTSGIKKALWSSDDKQILS-ADDKTVRLWDRSTMTEVKALN--VAMSVSSMEYVPEGqilvitygktiafhsaetleqik 219
           *********************9987766.69*********6666666663..4666666665555555555555555555555555555 PP
   S: 193  .................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
                            ++lv+g++d ++  +d+ tge +++++gh  ++ +vrfsp++e+++sgs+Dg++r+W ++ g++
   Q: 220  sfeapatinsaslhpekECLVAGGEDFKLYKYDYNTGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTTVGKT 300
           55555555555555555*********************************************************8776665 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MAMRQTPLTC SGHTRPVVDL AFSGVTPYGY FLISACKEDG KPMLRQGDTG DWIGTFLGHK 60
GAVWGATLNK DATKAATAAA DFTAKVWDAV SGDELITLAH KHIVKSVDFT QDSNYLLTGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCCCGAGC TCAGCCGCCG CCATGGCCAT GAGGCAGACC CCTCTGACGT GCTCCGGGCA 60
CACGCGGCCC GTGGTGGACC TGGCCTTCAG CGGCGTCACC CCCTACGGCT ACTTCCTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0032797--C:SMN complex
GO:0034719--C:SMN-Sm protein complex
GO:0003723--F:RNA binding
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0010633--P:negative regulation of epithelial cell migration
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0060394--P:negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000668	Aegilops tauschii	49.31	1.00e-73	269.00
IUUC-Aml-002091	Ailuropoda melanoleuca	85.16	1.00e-166	578.00
IUUC-Atr-002571	Amborella trichopoda	52.05	5.00e-77	280.00
IUUC-Apl-003327	Anas platyrhynchos	98.10	3.00e-159	553.00
IUUC-Aca-005324	Anolis carolinensis	91.74	4.00e-177	613.00
IUUC-Aly-006452	Arabidopsis lyrata	49.31	2.00e-75	275.00
IUUC-Ath-006646	Arabidopsis thaliana	49.31	2.00e-75	275.00
IUUC-Acl-008014	Aspergillus clavatus	41.54	2.00e-48	185.00
IUUC-Afl-008701	Aspergillus flavus	40.00	5.00e-33	134.00
IUUC-Afu-008942	Aspergillus fumigatus	30.85	2.00e-33	135.00
IUUC-Ani-009394	Aspergillus nidulans	40.84	1.00e-48	186.00
IUUC-Ang-009593	Aspergillus niger	38.18	2.00e-34	139.00
IUUC-Aor-010206	Aspergillus oryzae	42.56	2.00e-49	188.00
IUUC-Ame-011328	Astyanax mexicanus	81.41	8.00e-140	489.00
IUUC-Bgr-012308	Blumeria graminis	41.74	2.00e-57	215.00
IUUC-Bta-013429	Bos taurus	88.32	8.00e-166	575.00
IUUC-Bci-013803	Botrytis cinerea	41.09	8.00e-54	203.00
IUUC-Bdi-014996	Brachypodium distachyon	48.78	9.00e-74	269.00
IUUC-Bol-016595	Brassica oleracea	49.83	4.00e-77	281.00
IUUC-Bra-017775	Brassica rapa	48.64	7.00e-76	278.00
IUUC-Cja-018740	Callithrix jacchus	84.30	1.00e-162	565.00
IUUC-Cfa-021145	Canis familiaris	88.03	2.00e-166	577.00
IUUC-Cpo-022373	Cavia porcellus	88.03	6.00e-166	576.00
IUUC-Cre-022806	Chlamydomonas reinhardtii	44.37	4.00e-60	224.00
IUUC-Csa-023098	Chlorocebus sabaeus	87.18	1.00e-163	568.00
IUUC-Cho-024856	Choloepus hoffmanni	80.34	5.00e-144	503.00
IUUC-Cin-025541	Ciona intestinalis	59.21	1.00e-104	372.00
IUUC-Csv-026287	Ciona savignyi	58.28	1.00e-94	338.00
IUUC-Cgl-026513	Colletotrichum gloeosporioides	41.27	1.00e-52	199.00
IUUC-Cne-026869	Cryptococcus neoformans	47.00	2.00e-68	252.00
IUUC-Dre-028457	Danio rerio	74.43	1.00e-142	498.00
IUUC-Dno-029213	Dasypus novemcinctus	88.03	4.00e-168	583.00
IUUC-Dse-031350	Dothistroma septosporum	40.95	3.00e-50	191.00
IUUC-Dme-031857	Drosophila melanogaster	62.01	8.00e-105	372.00
IUUC-Ete-032558	Echinops telfairi	80.31	1.00e-109	388.00
IUUC-Eca-033934	Equus caballus	88.89	1.00e-166	578.00
IUUC-Eeu-034650	Erinaceus europaeus	75.21	9.00e-145	505.00
IUUC-Fca-035909	Felis catus	88.03	1.00e-166	578.00
IUUC-Fal-036706	Ficedula albicollis	98.41	1.00e-156	545.00
IUUC-Fox-037780	Fusarium oxysporum	42.14	7.00e-52	197.00
IUUC-Fso-038197	Fusarium solani	42.26	1.00e-54	206.00
IUUC-Gmo-039707	Gadus morhua	77.10	2.00e-130	457.00
IUUC-Ggr-040054	Gaeumannomyces graminis	40.48	4.00e-54	204.00
IUUC-Gga-040901	Gallus gallus	99.72	0.00e+00	644.00
IUUC-Gac-041876	Gasterosteus aculeatus	72.57	2.00e-138	484.00
IUUC-Gma-043984	Glycine max	51.37	6.00e-77	280.00
IUUC-Ggo-044583	Gorilla gorilla	81.25	9.00e-150	522.00
IUUC-Hsa-046553	Homo sapiens	84.02	4.00e-164	570.00
IUUC-Hvu-047544	Hordeum vulgare	49.83	1.00e-75	276.00
IUUC-Itr-047980	Ictidomys tridecemlineatus	88.32	1.00e-168	584.00
IUUC-Lch-050078	Latimeria chalumnae	80.40	3.00e-152	530.00
IUUC-Lpe-051246	Leersia perrieri	49.83	2.00e-76	278.00
IUUC-Loc-052598	Lepisosteus oculatus	76.99	1.00e-145	508.00
IUUC-Lma-053226	Leptosphaeria maculans	45.25	5.00e-56	210.00
IUUC-Laf-054053	Loxodonta africana	88.03	6.00e-168	582.00
IUUC-Mcc-054652	Macaca mulatta	84.34	1.00e-163	568.00
IUUC-Mor-057256	Magnaporthe oryzae	39.05	4.00e-52	197.00
IUUC-Mpo-057303	Magnaporthe poae	40.24	3.00e-54	205.00
IUUC-Mtr-058421	Medicago truncatula	51.03	7.00e-77	280.00
IUUC-Mla-059073	Melampsora laricipopulina	45.91	2.00e-63	235.00
IUUC-Mvi-060534	Microbotryum violaceum	35.79	8.00e-40	157.00
IUUC-Mmr-061044	Microcebus murinus	88.96	1.00e-159	555.00
IUUC-Mdo-063019	Monodelphis domestica	87.75	4.00e-167	580.00
IUUC-Mmu-064092	Mus musculus	89.17	7.00e-167	578.00
IUUC-Mac-065143	Musa acuminata	51.55	6.00e-76	276.00
IUUC-Mpu-066557	Mustela putorius furo	88.32	1.00e-168	584.00
IUUC-Mlu-068179	Myotis lucifugus	88.03	1.00e-167	582.00
IUUC-Nfi-068553	Neosartorya fischeri	41.54	7.00e-48	184.00
IUUC-Ncr-068934	Neurospora crassa	39.59	1.00e-48	186.00
IUUC-Nle-069482	Nomascus leucogenys	83.75	7.00e-163	566.00
IUUC-Opr-071055	Ochotona princeps	68.95	1.00e-115	409.00
IUUC-Ont-072663	Oreochromis niloticus	75.07	8.00e-138	482.00
IUUC-Ocu-074942	Oryctolagus cuniculus	88.60	3.00e-166	577.00
IUUC-Oba-075160	Oryza barthii	49.83	2.00e-76	278.00
IUUC-Obr-076864	Oryza brachyantha	49.83	2.00e-76	278.00
IUUC-Ogl-077076	Oryza glaberrima	49.83	2.00e-76	278.00
IUUC-Ogu-078591	Oryza glumaepatula	49.83	2.00e-76	278.00
IUUC-Oin-079631	Oryza indica	48.80	1.00e-74	273.00
IUUC-Olo-080389	Oryza longistaminata	42.92	2.00e-49	188.00
IUUC-Ome-081693	Oryza meridionalis	48.45	2.00e-73	268.00
IUUC-Oni-082190	Oryza nivara	50.17	1.00e-76	279.00
IUUC-Opu-084163	Oryza punctata	49.83	2.00e-76	278.00
IUUC-Oru-084730	Oryza rufipogon	49.83	2.00e-76	278.00
IUUC-Osa-086010	Oryza sativa	49.83	2.00e-76	278.00
IUUC-Ola-086704	Oryzias latipes	74.72	2.00e-143	501.00
IUUC-Olu-087796	Ostreococcus lucimarinus	51.86	1.00e-78	286.00
IUUC-Oga-088932	Otolemur garnettii	67.32	2.00e-111	395.00
IUUC-Oar-090398	Ovis aries	88.60	3.00e-166	577.00
IUUC-Ptr-091202	Pan troglodytes	86.89	2.00e-165	574.00
IUUC-Pan-091948	Papio anubis	87.46	2.00e-165	574.00
IUUC-Psi-093863	Pelodiscus sinensis	90.74	9.00e-158	548.00
IUUC-Pma-094255	Petromyzon marinus	79.03	1.00e-139	488.00
IUUC-Pno-095075	Phaeosphaeria nodorum	46.18	2.00e-57	215.00
IUUC-Ppa-095206	Physcomitrella patens	49.66	7.00e-81	293.00
IUUC-Pfo-096438	Poecilia formosa	75.57	1.00e-142	498.00
IUUC-Pab-097994	Pongo abelii	86.61	6.00e-165	572.00
IUUC-Pop-099172	Populus trichocarpa	50.52	4.00e-76	277.00
IUUC-Pca-100761	Procavia capensis	79.14	9.00e-138	482.00
IUUC-Ppe-102035	Prunus persica	51.37	1.00e-74	272.00
IUUC-Pva-102794	Pteropus vampyrus	80.34	5.00e-148	516.00
IUUC-Pgr-103581	Puccinia graminis	47.63	1.00e-64	239.00
IUUC-Ptt-103862	Puccinia triticina	47.42	5.00e-62	230.00
IUUC-Pte-104245	Pyrenophora teres	46.50	2.00e-58	218.00
IUUC-Pyt-104537	Pyrenophora triticirepentis	46.50	2.00e-58	218.00
IUUC-Rno-105712	Rattus norvegicus	88.89	2.00e-166	577.00
IUUC-Sha-107568	Sarcophilus harrisii	87.46	4.00e-167	579.00
IUUC-Ssl-108655	Sclerotinia sclerotiorum	40.23	5.00e-52	197.00
IUUC-Smo-108784	Selaginella moellendorffii	53.24	8.00e-82	296.00
IUUC-Sit-109807	Setaria italica	51.55	2.00e-77	282.00
IUUC-Sly-111555	Solanum lycopersicum	49.83	3.00e-75	275.00
IUUC-Stu-111953	Solanum tuberosum	49.14	2.00e-74	271.00
IUUC-Sar-113491	Sorex araneus	79.17	1.00e-109	388.00
IUUC-Sbi-114290	Sorghum bicolor	51.20	1.00e-77	282.00
IUUC-Sre-115008	Sporisorium reilianum	43.57	3.00e-61	228.00
IUUC-Ssc-116392	Sus scrofa	84.85	1.00e-163	568.00
IUUC-Tgu-116835	Taeniopygia guttata	98.09	1.00e-156	545.00
IUUC-Tru-117558	Takifugu rubripes	74.50	2.00e-142	498.00
IUUC-Tsy-119522	Tarsius syrichta	84.90	4.00e-154	536.00
IUUC-Tni-120330	Tetraodon nigroviridis	80.65	1.00e-136	478.00
IUUC-Tca-121759	Theobroma cacao	52.05	2.00e-76	278.00
IUUC-Tre-122163	Trichoderma reesei	42.56	7.00e-53	200.00
IUUC-Tvi-122609	Trichoderma virens	44.01	4.00e-54	204.00
IUUC-Tae-123053	Triticum aestivum	49.48	5.00e-75	274.00
IUUC-Tur-126808	Triticum urartu	46.51	7.00e-62	230.00
IUUC-Tme-127137	Tuber melanosporum	47.73	8.00e-68	249.00
IUUC-Tbe-127324	Tupaia belangeri	73.02	5.00e-80	290.00
IUUC-Ttr-128202	Tursiops truncatus	88.03	1.00e-164	572.00
IUUC-Uma-129433	Ustilago maydis	43.57	1.00e-59	223.00
IUUC-Vda-129675	Verticillium dahliae	38.82	1.00e-51	196.00
IUUC-Vpa-130382	Vicugna pacos	88.60	2.00e-166	577.00
IUUC-Vvi-130921	Vitis vinifera	51.71	4.00e-78	284.00
IUUC-Xtr-132648	Xenopus tropicalis	70.59	2.00e-130	457.00
IUUC-Xma-133969	Xiphophorus maculatus	71.59	5.00e-134	470.00
IUUC-Yli-134670	Yarrowia lipolytica	36.01	5.00e-44	171.00
IUUC-Zma-135878	Zea mays	51.20	8.00e-78	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence