iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssl-108387

Ensembl Protein ID

EDN92544

UniProt Accession

A7ESV2; A7ESV2_SCLS1

Genbank Protein ID

APA12929.1; EDN92544.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

CP017823; CH476631

Gene Name

SS1G_08407; sscle_10g076990

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SS1G_08407	EDN92544	EDN92544

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.40e-56	190.8	23	520

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllv..GagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           YDRQ+rlw + +q++l++a+ ll+  G g++G+E+lKnLvl G+g++t+ D + v+ ++l+ +F++++++ gks+Ae + + l+elnpdvn++ + +  + 
   Q: 23   YDRQLRLWAASGQAALENANLLLLnsGSGTVGVETLKNLVLPGIGKFTIADEALVNEADLGVNFFLDKDSLGKSRAEQCVKLLQELNPDVNGDWYPKLKDG 123
           ***********************7336789***************************************************************99876666 PP
   S: 100  leeeiv...FfkkfdvVvlaldnrearrkvnrlclna.rvpliesgtlGllGqvrviikgltecyscsd.....dppqktiPfctlketpn.......... 181
           + ++++     +k+++++         + +++   +  +vpl+++ + G++++ r++++g+  + + ++      ++++ +P+++l ++++          
   Q: 124  KIDQVFesdQQEKYTLIIYSFPIGPKILALAEKYSATyKVPLVSIHSAGFYSYFRTHLPGNFPIVDTHPdstatTDLRLLKPWPELSNFEAdltknidals 224
           666654666778889***99999999999998876645*********************986666555559999***************998888899998 PP
   S: 182  .aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv.. 274
             ++ +i++ vl+ ++l ++++++   + l+++ek+e+++ v+++ +       eenf+ea+++++k+ + +  ns +k+++++ + ++  +s+s+fw+  
   Q: 225  dHEHGHIPYLVLLLHFLRKWKEKHGSYP-LSYKEKTEFRTTVSNGTRRnnaeGGEENFDEAVAAVLKNISIRDLNSsVKEVFEYTPTEE--ESESDFWIia 322
           8999999999*******99999887776.889999999999988888755556799**************9999999*******99977..99******** PP
   S: 275  ..................................................................sfcsnaealq.........vpekvekdeevvkasa 300
                                                                              fc+na+ ++           +k++k+e +++++a
   Q: 323  davkrfyekhnelplpgsvpdmkaqsniyvqlqniykakarqdvqevletirahprgkeikvedveVFCKNAAFIKlirgsdpisNLQKIAKSESENDENA 423
           ******************************************************************99999999998777666656699999999888888 PP
   S: 301  p.lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiep.kldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknff 399
           p  ++ l  l    + ++ +  ++ +  + +    +++++    +e  ++++ +  +++ +e+a+   ++++ +++  gG++aqE+iK+++++++p++n+ 
   Q: 424  PfTMMPLSNLPIYLALRSTS--HVPLASSCE----ILAQID---REIPNSSSnPRIRKVAEEVARAKGGELHNISSLTGGMVAQEIIKIITKQYVPIDNTC 515
           85222233332222222222..233333333....222222...25555555558899999**************************************** PP
   S: 400  lfdae 404
           +fd++
   Q: 516  IFDGI 520
           **986 PP

Organism

Sclerotinia sclerotiorum

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MTEVVTEPTP PILQGPSDKE KKYDRQLRLW AASGQAALEN ANLLLLNSGS GTVGVETLKN 60
LVLPGIGKFT IADEALVNEA DLGVNFFLDK DSLGKSRAEQ CVKLLQELNP DVNGDWYPKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAGAAG TTGTCACAGA GCCCACCCCT CCCATCCTTC AAGGCCCTTC CGACAAGGAG 60
AAGAAATATG ATCGACAACT GCGATTATGG GCAGCCTCGG GGCAAGCAGC ATTGGAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

ssl:SS1G_08407

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	32.48	2.00e-59	221.00
IUUC-Aml-002333	Ailuropoda melanoleuca	32.84	1.00e-68	251.00
IUUC-Atr-002644	Amborella trichopoda	30.78	8.00e-50	189.00
IUUC-Apl-003446	Anas platyrhynchos	32.65	3.00e-60	224.00
IUUC-Aca-004450	Anolis carolinensis	31.62	5.00e-65	239.00
IUUC-Aly-005466	Arabidopsis lyrata	33.21	2.00e-62	231.00
IUUC-Ath-006692	Arabidopsis thaliana	33.03	2.00e-62	230.00
IUUC-Ago-007900	Ashbya gossypii	26.35	4.00e-34	137.00
IUUC-Acl-008333	Aspergillus clavatus	47.54	3.00e-129	453.00
IUUC-Afl-008529	Aspergillus flavus	47.99	1.00e-126	444.00
IUUC-Afu-009071	Aspergillus fumigatus	48.57	1.00e-133	468.00
IUUC-Ani-009443	Aspergillus nidulans	47.80	2.00e-124	437.00
IUUC-Ang-009669	Aspergillus niger	48.49	3.00e-142	496.00
IUUC-Aor-009914	Aspergillus oryzae	49.11	1.00e-128	451.00
IUUC-Ate-010450	Aspergillus terreus	47.89	3.00e-131	459.00
IUUC-Ame-011183	Astyanax mexicanus	33.95	2.00e-71	260.00
IUUC-Bgr-012111	Blumeria graminis	59.42	2.00e-168	583.00
IUUC-Bta-012583	Bos taurus	32.97	4.00e-69	253.00
IUUC-Bci-013892	Botrytis cinerea	85.28	0.00e+00	857.00
IUUC-Bdi-014592	Brachypodium distachyon	33.33	6.00e-61	226.00
IUUC-Bol-016401	Brassica oleracea	32.66	5.00e-62	229.00
IUUC-Bra-017506	Brassica rapa	33.88	3.00e-59	220.00
IUUC-Cel-018456	Caenorhabditis elegans	32.85	1.00e-59	221.00
IUUC-Cja-020007	Callithrix jacchus	32.01	3.00e-67	246.00
IUUC-Cfa-020324	Canis familiaris	32.66	2.00e-69	254.00
IUUC-Cpo-022248	Cavia porcellus	30.37	5.00e-36	142.00
IUUC-Csa-023149	Chlorocebus sabaeus	28.60	3.00e-49	187.00
IUUC-Cho-024537	Choloepus hoffmanni	25.26	1.00e-33	135.00
IUUC-Cin-025763	Ciona intestinalis	34.43	4.00e-71	259.00
IUUC-Csv-026113	Ciona savignyi	35.94	8.00e-74	268.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	57.61	3.00e-164	569.00
IUUC-Cne-026884	Cryptococcus neoformans	32.27	1.00e-48	185.00
IUUC-Dre-028140	Danio rerio	32.41	9.00e-68	248.00
IUUC-Dno-030033	Dasypus novemcinctus	34.47	7.00e-60	222.00
IUUC-Dor-030513	Dipodomys ordii	55.45	4.00e-20	90.50
IUUC-Dse-031536	Dothistroma septosporum	45.56	4.00e-131	459.00
IUUC-Dme-031683	Drosophila melanogaster	35.07	6.00e-71	259.00
IUUC-Ete-032420	Echinops telfairi	27.82	9.00e-48	182.00
IUUC-Eca-033992	Equus caballus	28.10	4.00e-46	176.00
IUUC-Eeu-034713	Erinaceus europaeus	57.14	5.00e-22	97.10
IUUC-Fca-036548	Felis catus	32.43	7.00e-68	249.00
IUUC-Fal-037600	Ficedula albicollis	31.65	2.00e-58	217.00
IUUC-Fox-038037	Fusarium oxysporum	59.51	1.00e-178	617.00
IUUC-Fso-038387	Fusarium solani	58.54	0.00e+00	626.00
IUUC-Gmo-038562	Gadus morhua	32.35	6.00e-65	239.00
IUUC-Ggr-040005	Gaeumannomyces graminis	61.68	1.00e-180	623.00
IUUC-Gga-041129	Gallus gallus	32.90	6.00e-64	236.00
IUUC-Gac-042558	Gasterosteus aculeatus	33.15	1.00e-65	241.00
IUUC-Gma-043610	Glycine max	31.79	9.00e-59	218.00
IUUC-Ggo-045611	Gorilla gorilla	32.37	3.00e-67	246.00
IUUC-Hsa-046563	Homo sapiens	32.55	1.00e-68	251.00
IUUC-Hvu-047790	Hordeum vulgare	29.90	5.00e-40	156.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	32.36	1.00e-68	251.00
IUUC-Kpa-049309	Komagataella pastoris	34.48	1.00e-68	251.00
IUUC-Lch-050038	Latimeria chalumnae	31.62	3.00e-65	240.00
IUUC-Lpe-051535	Leersia perrieri	30.73	1.00e-41	161.00
IUUC-Loc-051917	Lepisosteus oculatus	31.96	1.00e-54	204.00
IUUC-Lma-053112	Leptosphaeria maculans	48.23	4.00e-138	482.00
IUUC-Laf-053690	Loxodonta africana	32.60	3.00e-69	253.00
IUUC-Mcc-055117	Macaca mulatta	31.41	3.00e-63	233.00
IUUC-Meu-056761	Macropus eugenii	29.00	8.00e-35	139.00
IUUC-Mor-057230	Magnaporthe oryzae	59.55	0.00e+00	637.00
IUUC-Mpo-057514	Magnaporthe poae	61.87	2.00e-179	619.00
IUUC-Mtr-058551	Medicago truncatula	32.61	5.00e-55	206.00
IUUC-Mla-059183	Melampsora laricipopulina	35.20	6.00e-71	259.00
IUUC-Mga-060144	Meleagris gallopavo	32.04	9.00e-61	225.00
IUUC-Mvi-060221	Microbotryum violaceum	34.90	1.00e-71	261.00
IUUC-Mmr-061325	Microcebus murinus	31.71	1.00e-64	238.00
IUUC-Mdo-062532	Monodelphis domestica	33.27	1.00e-68	251.00
IUUC-Mmu-063956	Mus musculus	33.33	2.00e-71	261.00
IUUC-Mac-064521	Musa acuminata	33.39	3.00e-60	223.00
IUUC-Mpu-066716	Mustela putorius furo	34.26	1.00e-60	225.00
IUUC-Mlu-067459	Myotis lucifugus	32.00	4.00e-68	250.00
IUUC-Nfi-068245	Neosartorya fischeri	48.57	2.00e-132	463.00
IUUC-Ncr-068910	Neurospora crassa	59.42	2.00e-179	620.00
IUUC-Nle-070034	Nomascus leucogenys	30.13	2.00e-59	221.00
IUUC-Opr-070552	Ochotona princeps	31.59	3.00e-47	180.00
IUUC-Ont-071426	Oreochromis niloticus	34.13	5.00e-71	259.00
IUUC-Oan-073389	Ornithorhynchus anatinus	29.34	3.00e-44	170.00
IUUC-Ocu-074911	Oryctolagus cuniculus	32.25	5.00e-68	249.00
IUUC-Oba-075437	Oryza barthii	32.18	6.00e-52	196.00
IUUC-Obr-076684	Oryza brachyantha	31.91	1.00e-47	181.00
IUUC-Ogl-077170	Oryza glaberrima	32.18	6.00e-52	196.00
IUUC-Ogu-078844	Oryza glumaepatula	31.55	1.00e-43	168.00
IUUC-Oin-079105	Oryza indica	32.30	3.00e-52	197.00
IUUC-Olo-080943	Oryza longistaminata	30.21	2.00e-36	144.00
IUUC-Oni-082891	Oryza nivara	31.02	3.00e-45	174.00
IUUC-Opu-083457	Oryza punctata	32.55	3.00e-51	193.00
IUUC-Oru-084960	Oryza rufipogon	30.21	3.00e-36	144.00
IUUC-Osa-085358	Oryza sativa	32.23	7.00e-52	196.00
IUUC-Ola-086420	Oryzias latipes	30.38	6.00e-45	172.00
IUUC-Olu-087625	Ostreococcus lucimarinus	28.19	2.00e-34	138.00
IUUC-Oga-088810	Otolemur garnettii	32.96	3.00e-69	253.00
IUUC-Oar-089196	Ovis aries	32.73	8.00e-68	249.00
IUUC-Ptr-090617	Pan troglodytes	32.36	6.00e-68	249.00
IUUC-Pan-092761	Papio anubis	32.55	3.00e-69	253.00
IUUC-Psi-093191	Pelodiscus sinensis	31.27	8.00e-60	222.00
IUUC-Pma-094380	Petromyzon marinus	38.60	5.00e-61	226.00
IUUC-Pno-095084	Phaeosphaeria nodorum	45.60	2.00e-121	428.00
IUUC-Ppa-095798	Physcomitrella patens	31.09	2.00e-59	221.00
IUUC-Pfo-096467	Poecilia formosa	34.06	3.00e-65	240.00
IUUC-Pab-098255	Pongo abelii	34.72	6.00e-61	226.00
IUUC-Pop-099871	Populus trichocarpa	32.36	3.00e-60	223.00
IUUC-Pca-100807	Procavia capensis	37.50	7.00e-22	95.90
IUUC-Ppe-101280	Prunus persica	30.95	7.00e-58	216.00
IUUC-Pva-102333	Pteropus vampyrus	32.23	3.00e-62	230.00
IUUC-Pgr-103401	Puccinia graminis	29.81	1.00e-60	225.00
IUUC-Ptt-103889	Puccinia triticina	28.57	1.00e-55	209.00
IUUC-Pte-104355	Pyrenophora teres	48.59	7.00e-142	494.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	49.03	2.00e-141	493.00
IUUC-Rno-105810	Rattus norvegicus	32.36	1.00e-68	251.00
IUUC-Sce-106397	Saccharomyces cerevisiae	24.81	3.00e-25	107.00
IUUC-Sha-106770	Sarcophilus harrisii	39.64	4.00e-42	162.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	31.20	4.00e-59	220.00
IUUC-Spo-108276	Schizosaccharomyces pombe	33.88	2.00e-64	237.00
IUUC-Smo-109296	Selaginella moellendorffii	33.40	1.00e-64	238.00
IUUC-Sit-110157	Setaria italica	33.21	2.00e-61	228.00
IUUC-Sly-111105	Solanum lycopersicum	31.26	2.00e-58	217.00
IUUC-Stu-112469	Solanum tuberosum	31.75	7.00e-60	222.00
IUUC-Sbi-113813	Sorghum bicolor	32.69	5.00e-61	226.00
IUUC-Sre-115058	Sporisorium reilianum	34.75	2.00e-56	211.00
IUUC-Tgu-116772	Taeniopygia guttata	31.01	1.00e-58	218.00
IUUC-Tru-118686	Takifugu rubripes	32.66	7.00e-68	249.00
IUUC-Tsy-119111	Tarsius syrichta	35.14	7.00e-33	132.00
IUUC-Tni-120231	Tetraodon nigroviridis	29.04	1.00e-58	218.00
IUUC-Tca-121491	Theobroma cacao	31.18	7.00e-54	202.00
IUUC-Tre-122103	Trichoderma reesei	59.07	7.00e-180	621.00
IUUC-Tvi-122672	Trichoderma virens	59.93	7.00e-175	604.00
IUUC-Tae-125316	Triticum aestivum	32.60	1.00e-60	224.00
IUUC-Tur-126487	Triticum urartu	31.49	4.00e-55	206.00
IUUC-Tme-127097	Tuber melanosporum	41.20	5.00e-97	345.00
IUUC-Ttr-128465	Tursiops truncatus	30.07	8.00e-56	209.00
IUUC-Uma-129645	Ustilago maydis	32.72	3.00e-56	210.00
IUUC-Vda-129989	Verticillium dahliae	50.74	7.00e-137	478.00
IUUC-Vpa-130529	Vicugna pacos	30.83	4.00e-59	220.00
IUUC-Vvi-131059	Vitis vinifera	31.44	7.00e-55	206.00
IUUC-Xtr-132002	Xenopus tropicalis	34.68	2.00e-73	267.00
IUUC-Xma-133930	Xiphophorus maculatus	33.83	3.00e-66	243.00
IUUC-Yli-134505	Yarrowia lipolytica	38.00	1.00e-80	291.00
IUUC-Zma-135895	Zea mays	32.79	3.00e-60	223.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence