iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074923

UUCD1 version

UUC-OrC-01028

Ensembl Protein ID

ENSOCUP00000014635.3

UniProt Accession

G1TCV5; G1TCV5_RABIT

Protein Name

Uncharacterized protein

Gene Name

USP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000017031.3	ENSOCUT00000017032.3	ENSOCUP00000014635.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-98	329.8	91	420

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re++l  +k +      +++k++ll++l++lf+++   k+k +++ p+++++ l+ke+  f++y
   Q: 91   FGLVNFGNTCYCNSVLQALYFCRPFRENVLA-YKAQ------QKKKENLLTCLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNY 172
           6******************************.3333......567899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l   ++++k+e+++ + ++ +++++ +++k + ++++++Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 173  MQQDAHEFLNYLLNTIADIL---QEEKKQEKQNGKLKNGNMNEPAENNKAELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV 258
           ********************...44555555555556667777888888899************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL++f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+
   Q: 259  EQNT-----SITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FN 340
           ****.....9**********************************************************************66555..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts++  ++ ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 341  TSSDA-VNLDRMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 420
           77554.4459***************************.888*******************999*****************97 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MQRNRGSLAL QESCAPWESP GCLAEMQVLV LQMLPQAHLR TCCRWPSAYI FHRVEESRSG 60
TLPGSLKEGT NASALEKDIG PEQFPINEHY FGLVNFGNTC YCNSVLQALY FCRPFRENVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCCCAGT CTCAGAATTT GTGACTGTCA CGGTGGGTTT AGGTTGTTGG GGTGGGGTTC 60
AGGTACCGCA AGAGTGTGTG TGTGTGTGTG TGTGTGTGTG TGGTATTTAT GTGCCACGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008343--P:adult feeding behavior
GO:0001662--P:behavioral fear response
GO:0048149--P:behavioral response to ethanol
GO:0016579--P:protein deubiquitination
GO:0032228--P:regulation of synaptic transmission, GABAergic
GO:0060013--P:righting reflex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000193	Aegilops tauschii	59.62	6.00e-124	437.00
IUUC-Aml-002353	Ailuropoda melanoleuca	97.79	0.00e+00	694.00
IUUC-Atr-002650	Amborella trichopoda	60.00	6.00e-124	437.00
IUUC-Apl-003380	Anas platyrhynchos	98.59	0.00e+00	687.00
IUUC-Aca-005031	Anolis carolinensis	97.18	0.00e+00	725.00
IUUC-Aly-005830	Arabidopsis lyrata	58.54	5.00e-122	430.00
IUUC-Ath-006663	Arabidopsis thaliana	58.54	3.00e-125	441.00
IUUC-Ago-007871	Ashbya gossypii	38.23	3.00e-49	190.00
IUUC-Ame-010862	Astyanax mexicanus	94.68	0.00e+00	699.00
IUUC-Bta-013023	Bos taurus	96.75	0.00e+00	699.00
IUUC-Bdi-014008	Brachypodium distachyon	60.44	2.00e-124	439.00
IUUC-Bol-015138	Brassica oleracea	58.49	6.00e-124	436.00
IUUC-Bra-017483	Brassica rapa	59.94	2.00e-124	438.00
IUUC-Cel-018379	Caenorhabditis elegans	62.22	1.00e-144	506.00
IUUC-Cja-018956	Callithrix jacchus	99.16	0.00e+00	695.00
IUUC-Cfa-021064	Canis familiaris	98.87	0.00e+00	686.00
IUUC-Cpo-022443	Cavia porcellus	99.15	0.00e+00	694.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	53.24	7.00e-98	350.00
IUUC-Csa-023841	Chlorocebus sabaeus	99.72	0.00e+00	695.00
IUUC-Cne-026900	Cryptococcus neoformans	41.91	3.00e-60	226.00
IUUC-Dre-028230	Danio rerio	94.15	0.00e+00	698.00
IUUC-Dno-029209	Dasypus novemcinctus	98.61	0.00e+00	693.00
IUUC-Dme-032038	Drosophila melanogaster	80.88	4.00e-100	358.00
IUUC-Eca-033721	Equus caballus	99.44	0.00e+00	692.00
IUUC-Eeu-034916	Erinaceus europaeus	98.30	3.00e-161	560.00
IUUC-Fca-036299	Felis catus	99.16	0.00e+00	696.00
IUUC-Fox-037682	Fusarium oxysporum	42.01	4.00e-73	269.00
IUUC-Fso-038299	Fusarium solani	36.83	1.00e-73	271.00
IUUC-Gmo-038611	Gadus morhua	94.63	0.00e+00	693.00
IUUC-Ggr-039806	Gaeumannomyces graminis	42.86	8.00e-75	275.00
IUUC-Gga-041157	Gallus gallus	98.59	0.00e+00	688.00
IUUC-Gac-041764	Gasterosteus aculeatus	93.91	0.00e+00	698.00
IUUC-Gma-042927	Glycine max	60.55	3.00e-126	444.00
IUUC-Ggo-044659	Gorilla gorilla	99.72	0.00e+00	694.00
IUUC-Hsa-046156	Homo sapiens	99.72	0.00e+00	695.00
IUUC-Hvu-047692	Hordeum vulgare	58.49	2.00e-122	432.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	99.72	0.00e+00	695.00
IUUC-Kpa-049250	Komagataella pastoris	44.83	1.00e-69	257.00
IUUC-Lch-049969	Latimeria chalumnae	96.33	0.00e+00	656.00
IUUC-Lpe-051368	Leersia perrieri	59.34	2.00e-121	429.00
IUUC-Loc-052479	Lepisosteus oculatus	91.24	0.00e+00	670.00
IUUC-Laf-054085	Loxodonta africana	99.72	0.00e+00	695.00
IUUC-Mcc-055566	Macaca mulatta	99.72	0.00e+00	695.00
IUUC-Mtr-057715	Medicago truncatula	60.55	2.00e-126	444.00
IUUC-Mla-059142	Melampsora laricipopulina	53.74	5.00e-95	342.00
IUUC-Mga-059575	Meleagris gallopavo	98.31	0.00e+00	686.00
IUUC-Mvi-060357	Microbotryum violaceum	53.02	2.00e-77	284.00
IUUC-Mdo-062579	Monodelphis domestica	99.44	0.00e+00	694.00
IUUC-Mmu-063611	Mus musculus	99.72	0.00e+00	695.00
IUUC-Mac-065323	Musa acuminata	60.00	3.00e-123	434.00
IUUC-Mpu-066038	Mustela putorius furo	99.44	0.00e+00	694.00
IUUC-Mlu-068183	Myotis lucifugus	99.15	0.00e+00	694.00
IUUC-Nle-069330	Nomascus leucogenys	99.72	0.00e+00	695.00
IUUC-Opr-070980	Ochotona princeps	99.44	0.00e+00	693.00
IUUC-Ont-072134	Oreochromis niloticus	94.96	0.00e+00	704.00
IUUC-Oan-073583	Ornithorhynchus anatinus	93.50	0.00e+00	682.00
IUUC-Oba-075220	Oryza barthii	59.62	5.00e-122	430.00
IUUC-Obr-076208	Oryza brachyantha	57.42	1.00e-118	419.00
IUUC-Ogl-077216	Oryza glaberrima	59.62	5.00e-122	430.00
IUUC-Ogu-078836	Oryza glumaepatula	59.62	5.00e-122	430.00
IUUC-Oin-079522	Oryza indica	59.62	5.00e-122	430.00
IUUC-Olo-080882	Oryza longistaminata	59.62	5.00e-122	430.00
IUUC-Ome-081549	Oryza meridionalis	59.62	5.00e-122	430.00
IUUC-Oni-082982	Oryza nivara	59.62	5.00e-122	430.00
IUUC-Opu-083532	Oryza punctata	59.62	2.00e-122	431.00
IUUC-Oru-084568	Oryza rufipogon	59.62	5.00e-122	430.00
IUUC-Osa-085299	Oryza sativa	59.62	5.00e-122	430.00
IUUC-Ola-086546	Oryzias latipes	94.97	0.00e+00	706.00
IUUC-Olu-087809	Ostreococcus lucimarinus	48.44	3.00e-81	295.00
IUUC-Oga-088073	Otolemur garnettii	99.44	0.00e+00	692.00
IUUC-Oar-089248	Ovis aries	99.44	0.00e+00	694.00
IUUC-Ptr-090814	Pan troglodytes	99.72	0.00e+00	695.00
IUUC-Pan-091753	Papio anubis	99.72	0.00e+00	695.00
IUUC-Psi-094012	Pelodiscus sinensis	98.60	0.00e+00	690.00
IUUC-Ppa-095415	Physcomitrella patens	58.65	7.00e-126	443.00
IUUC-Pfo-097369	Poecilia formosa	94.96	0.00e+00	704.00
IUUC-Pab-098594	Pongo abelii	99.72	0.00e+00	695.00
IUUC-Pop-099798	Populus trichocarpa	60.00	2.00e-125	442.00
IUUC-Pca-100913	Procavia capensis	83.62	2.00e-158	551.00
IUUC-Ppe-101474	Prunus persica	59.45	9.00e-126	442.00
IUUC-Pva-102892	Pteropus vampyrus	99.72	0.00e+00	694.00
IUUC-Pgr-103306	Puccinia graminis	52.98	1.00e-95	345.00
IUUC-Rno-104909	Rattus norvegicus	99.44	0.00e+00	694.00
IUUC-Sha-107400	Sarcophilus harrisii	99.44	0.00e+00	692.00
IUUC-Smo-109064	Selaginella moellendorffii	60.22	6.00e-120	423.00
IUUC-Sit-110819	Setaria italica	59.18	9.00e-123	433.00
IUUC-Sly-111165	Solanum lycopersicum	59.78	4.00e-126	444.00
IUUC-Stu-112398	Solanum tuberosum	60.06	6.00e-126	443.00
IUUC-Sbi-114724	Sorghum bicolor	59.34	1.00e-122	432.00
IUUC-Ssc-115550	Sus scrofa	99.72	0.00e+00	695.00
IUUC-Tgu-116800	Taeniopygia guttata	98.59	0.00e+00	688.00
IUUC-Tru-118212	Takifugu rubripes	94.96	0.00e+00	706.00
IUUC-Tni-120071	Tetraodon nigroviridis	95.24	0.00e+00	707.00
IUUC-Tca-121329	Theobroma cacao	60.00	1.00e-125	442.00
IUUC-Tae-124807	Triticum aestivum	59.62	3.00e-124	437.00
IUUC-Tur-126563	Triticum urartu	59.62	3.00e-124	437.00
IUUC-Uma-129409	Ustilago maydis	49.13	2.00e-81	297.00
IUUC-Vpa-130590	Vicugna pacos	94.92	0.00e+00	648.00
IUUC-Vvi-131371	Vitis vinifera	59.45	2.00e-125	441.00
IUUC-Xma-133111	Xiphophorus maculatus	94.96	0.00e+00	703.00
IUUC-Yli-134632	Yarrowia lipolytica	44.86	8.00e-79	288.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence