iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061995

UUCD1 version

UUC-MoD-00845

Ensembl Protein ID

ENSMODP00000037487.1

UniProt Accession

F7F5Y4; F7F5Y4_MONDO

Protein Name

Uncharacterized protein

Gene Name

ENC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000025244.1	ENSMODT00000039084.1	ENSMODP00000037487.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.00e-20	74.0	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.30e-08	32.1	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l+ g++ f++h++vLaa+S++F+a+f+++l+es+ +++v+++  + pev++ ll++ Y++++ +ne
   Q: 46   TDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQ-SSEVNFDNsIHPEVLELLLDYAYSSRVIINE 114
           7************************************9.*******77******************9987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclg+l ++d+++c++L++   +++l++F+
   Q: 146  PTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQ 177
           78*****************************6 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSVSMHENRK SRASTGSINI YLFHKSSYAD SVLTHLNLLR QQRLFTDVLL HAGNRTFPCH 60
RAVLAACSRY FEAMFSGGLK ESQSSEVNFD NSIHPEVLEL LLDYAYSSRV IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGTCA GCATGCATGA AAATCGCAAA TCTCGGGCCA GCACTGGCTC AATTAATATA 60
TACTTGTTCC ATAAATCCTC ATATGCTGAC AGTGTCCTCA CACATCTGAA TCTTTTGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR030562--ENC1
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0017148--P:negative regulation of translation
GO:0007399--P:nervous system development
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

mdo:100011601

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001434	Ailuropoda melanoleuca	98.64	0.00e+00	1180.00
IUUC-Apl-004096	Anas platyrhynchos	98.30	0.00e+00	1180.00
IUUC-Aca-004884	Anolis carolinensis	97.62	0.00e+00	1170.00
IUUC-Ame-011321	Astyanax mexicanus	89.13	0.00e+00	1120.00
IUUC-Bta-013178	Bos taurus	98.47	0.00e+00	1179.00
IUUC-Cja-019494	Callithrix jacchus	98.64	0.00e+00	1180.00
IUUC-Cfa-020824	Canis familiaris	98.64	0.00e+00	1180.00
IUUC-Cpo-021874	Cavia porcellus	98.30	0.00e+00	1176.00
IUUC-Csa-023075	Chlorocebus sabaeus	98.64	0.00e+00	1180.00
IUUC-Cho-024542	Choloepus hoffmanni	98.64	0.00e+00	1179.00
IUUC-Dre-028448	Danio rerio	89.13	0.00e+00	1123.00
IUUC-Dno-029952	Dasypus novemcinctus	98.98	0.00e+00	1183.00
IUUC-Dor-030844	Dipodomys ordii	98.64	0.00e+00	1180.00
IUUC-Ete-032817	Echinops telfairi	91.51	0.00e+00	1088.00
IUUC-Eca-033651	Equus caballus	98.64	0.00e+00	1180.00
IUUC-Fca-036541	Felis catus	98.64	0.00e+00	1180.00
IUUC-Fal-036968	Ficedula albicollis	98.30	0.00e+00	1179.00
IUUC-Gmo-038821	Gadus morhua	88.46	0.00e+00	1108.00
IUUC-Gga-040468	Gallus gallus	98.30	0.00e+00	1180.00
IUUC-Gac-041686	Gasterosteus aculeatus	89.81	0.00e+00	1123.00
IUUC-Ggo-044621	Gorilla gorilla	98.64	0.00e+00	1180.00
IUUC-Hsa-046983	Homo sapiens	98.47	0.00e+00	1177.00
IUUC-Itr-048320	Ictidomys tridecemlineatus	98.47	0.00e+00	1178.00
IUUC-Lch-049735	Latimeria chalumnae	92.87	0.00e+00	1112.00
IUUC-Loc-052350	Lepisosteus oculatus	92.02	0.00e+00	1146.00
IUUC-Laf-054117	Loxodonta africana	98.64	0.00e+00	1181.00
IUUC-Mcc-054626	Macaca mulatta	98.64	0.00e+00	1180.00
IUUC-Meu-056763	Macropus eugenii	99.83	0.00e+00	1194.00
IUUC-Mmr-060579	Microcebus murinus	98.64	0.00e+00	1180.00
IUUC-Mmu-064206	Mus musculus	98.47	0.00e+00	1179.00
IUUC-Mpu-066884	Mustela putorius furo	98.64	0.00e+00	1180.00
IUUC-Mlu-067183	Myotis lucifugus	98.64	0.00e+00	1180.00
IUUC-Nle-069928	Nomascus leucogenys	98.64	0.00e+00	1180.00
IUUC-Opr-070238	Ochotona princeps	98.47	0.00e+00	1176.00
IUUC-Ont-072404	Oreochromis niloticus	90.15	0.00e+00	1127.00
IUUC-Oan-073303	Ornithorhynchus anatinus	98.81	0.00e+00	1183.00
IUUC-Ocu-074119	Oryctolagus cuniculus	98.30	0.00e+00	1176.00
IUUC-Ola-087510	Oryzias latipes	90.09	0.00e+00	1079.00
IUUC-Oga-089119	Otolemur garnettii	98.64	0.00e+00	1180.00
IUUC-Oar-090036	Ovis aries	92.02	0.00e+00	1054.00
IUUC-Ptr-091349	Pan troglodytes	98.64	0.00e+00	1180.00
IUUC-Pan-092098	Papio anubis	98.64	0.00e+00	1180.00
IUUC-Pma-094515	Petromyzon marinus	60.35	0.00e+00	679.00
IUUC-Pfo-097496	Poecilia formosa	90.66	0.00e+00	1133.00
IUUC-Pab-098388	Pongo abelii	98.64	0.00e+00	1180.00
IUUC-Pca-100511	Procavia capensis	90.15	0.00e+00	1057.00
IUUC-Pva-102964	Pteropus vampyrus	98.64	0.00e+00	1180.00
IUUC-Rno-106059	Rattus norvegicus	98.64	0.00e+00	1181.00
IUUC-Sha-106470	Sarcophilus harrisii	100.00	0.00e+00	1195.00
IUUC-Sar-113403	Sorex araneus	97.96	0.00e+00	1212.00
IUUC-Ssc-115566	Sus scrofa	98.64	0.00e+00	1180.00
IUUC-Tgu-117331	Taeniopygia guttata	98.13	0.00e+00	1177.00
IUUC-Tru-117890	Takifugu rubripes	89.64	0.00e+00	1120.00
IUUC-Xtr-131810	Xenopus tropicalis	94.23	0.00e+00	1148.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence