iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092551

Ensembl Protein ID

ENSPANP00000018759.1

UniProt Accession

A0A096P084; A0A096P084_PAPAN

Genbank Protein ID

ENSPANP00000018759

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01002341

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000007753.1	ENSPANT00000028762.1	ENSPANP00000018759.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.20e-61	206.5	416	781

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +   +  +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 416  GLINKGNWCYINATLQALVACPPMYHLMKF-IPLYSK-VQRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkivrdirpgaAFEPT 502
           9***************************99.333333.334799***************7666654333337777888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsdeaeekkkkknk... 139
            +++ l   ++++s + +q+Da+E+l f+l++l+ee+ +                  +n++++eee+e++ e s++++e+   +nk   
   Q: 503  YIYRLLTVNKSSLSeKGRQEDAEEYLGFILNGLHEEMLNlkkllspnnekltisngPQNHSVTEEEQEEQGEGSEDEWEQVGPRNKtsv 591
           ******99999866599********************4456689999999999999899999999888888888887777777777777 PP
   S: 140  ........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekk 220
                   ++i+ +F+g+++ +++ ++  ++s + +pf++l+l++                  +++e+++g    y++k k+++e +++
   Q: 592  trqadfvqTPITGIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIXL----------------VARESVQG----YTTKTKQEVEISRR 659
           77887888***********9.688999999***************84................55899997....99999********* PP
   S: 221  lklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYvayvknekgk 305
           ++l+klP+vL+lhLkRf ++++++++ k+ k++e+p  L++s+ + sp  k+k+   +++Y+L+avv+H+G s+ +GHY+++v +   +
   Q: 660  VTLEKLPPVLVLHLKRFVYEKTGGCQ-KLIKNIEYPVDLEISKELLSPGVKNKNfkcHRTYRLFAVVYHHGnSATGGHYTTDVFQIGLN 747
           *******************9998886.****************999988777777879***************************8777 PP
   S: 306  .WllfdDskVtevkeeevleetg.staYvlfYkr 337
            Wl++dD++V+++++ +v++ t+ +taY+l+Y+r
   Q: 748  gWLRIDDQTVKVISQYQVVKPTAeRTAYLLYYRR 781
           7*******************9889********98 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MALHSPQYIF GDFSPDEFNQ FFVTPRSSVE LPPYSGTVLC GTQAVDKLPD GQEYQRIEFG 60
VNEVIEPSDT LPRTPSYSIS STLNPQAPEF ILGCTTSKTT PDGITKEANY GSIDCQYPGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCCGCGGC GCGCGGCCAG TGCGCAGGCG CGGCGGCCGA TGCGAGTGTG TATGTGCGGG 60
CGAGAAGATG GCGGCGGCGG GGGAAGCAGC GTGAGCAGCC GGAGGAACGC CGAGTCTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	31.38	2.00e-42	167.00
IUUC-Aml-001584	Ailuropoda melanoleuca	86.36	0.00e+00	1295.00
IUUC-Atr-002927	Amborella trichopoda	33.59	2.00e-52	200.00
IUUC-Apl-003988	Anas platyrhynchos	76.86	0.00e+00	1113.00
IUUC-Aca-004461	Anolis carolinensis	84.73	2.00e-153	535.00
IUUC-Aly-006038	Arabidopsis lyrata	34.87	1.00e-48	187.00
IUUC-Ath-007328	Arabidopsis thaliana	34.62	2.00e-47	183.00
IUUC-Ago-007717	Ashbya gossypii	29.28	4.00e-40	159.00
IUUC-Acl-008188	Aspergillus clavatus	31.85	3.00e-57	216.00
IUUC-Afl-008456	Aspergillus flavus	35.76	3.00e-42	165.00
IUUC-Afu-009067	Aspergillus fumigatus	34.83	5.00e-60	226.00
IUUC-Ani-009483	Aspergillus nidulans	32.39	3.00e-57	216.00
IUUC-Ang-009639	Aspergillus niger	34.18	5.00e-55	209.00
IUUC-Aor-010040	Aspergillus oryzae	34.15	2.00e-54	207.00
IUUC-Ate-010310	Aspergillus terreus	32.63	4.00e-56	213.00
IUUC-Ame-011012	Astyanax mexicanus	71.74	1.00e-153	536.00
IUUC-Bgr-012311	Blumeria graminis	33.51	4.00e-38	153.00
IUUC-Bta-013299	Bos taurus	85.00	0.00e+00	1237.00
IUUC-Bci-013783	Botrytis cinerea	35.48	1.00e-53	204.00
IUUC-Bdi-015039	Brachypodium distachyon	30.38	1.00e-43	171.00
IUUC-Bol-015806	Brassica oleracea	35.71	1.00e-56	214.00
IUUC-Bra-017076	Brassica rapa	35.97	7.00e-57	214.00
IUUC-Cja-018715	Callithrix jacchus	93.43	0.00e+00	1434.00
IUUC-Cfa-020194	Canis familiaris	87.63	0.00e+00	1315.00
IUUC-Cpo-022272	Cavia porcellus	73.02	0.00e+00	1020.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	32.78	8.00e-29	121.00
IUUC-Csa-023310	Chlorocebus sabaeus	97.10	0.00e+00	1481.00
IUUC-Cho-024966	Choloepus hoffmanni	79.01	0.00e+00	965.00
IUUC-Cin-025616	Ciona intestinalis	46.51	2.00e-100	359.00
IUUC-Csv-026043	Ciona savignyi	45.48	1.00e-94	339.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	32.79	2.00e-42	167.00
IUUC-Cne-026962	Cryptococcus neoformans	33.61	3.00e-45	177.00
IUUC-Cme-027113	Cyanidioschyzon merolae	29.98	9.00e-32	131.00
IUUC-Dre-028072	Danio rerio	75.91	0.00e+00	687.00
IUUC-Dno-029489	Dasypus novemcinctus	87.01	0.00e+00	1340.00
IUUC-Dor-031068	Dipodomys ordii	69.09	2.00e-126	446.00
IUUC-Dse-031553	Dothistroma septosporum	35.84	1.00e-52	201.00
IUUC-Dme-031759	Drosophila melanogaster	40.00	2.00e-79	291.00
IUUC-Ete-032549	Echinops telfairi	75.74	0.00e+00	851.00
IUUC-Eca-033380	Equus caballus	85.12	0.00e+00	1307.00
IUUC-Eeu-034818	Erinaceus europaeus	82.23	0.00e+00	1229.00
IUUC-Fca-035535	Felis catus	84.59	0.00e+00	1168.00
IUUC-Fal-036627	Ficedula albicollis	74.43	0.00e+00	1066.00
IUUC-Fox-037904	Fusarium oxysporum	34.82	3.00e-47	183.00
IUUC-Fso-038170	Fusarium solani	31.76	3.00e-46	180.00
IUUC-Gmo-039499	Gadus morhua	67.93	0.00e+00	633.00
IUUC-Ggr-040042	Gaeumannomyces graminis	34.31	1.00e-55	211.00
IUUC-Gga-040571	Gallus gallus	76.38	0.00e+00	1108.00
IUUC-Gac-041345	Gasterosteus aculeatus	74.14	0.00e+00	634.00
IUUC-Gma-043436	Glycine max	33.59	2.00e-53	203.00
IUUC-Ggo-044652	Gorilla gorilla	95.86	0.00e+00	1504.00
IUUC-Hsa-045864	Homo sapiens	96.12	0.00e+00	1511.00
IUUC-Hvu-047071	Hordeum vulgare	31.25	2.00e-46	179.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	87.48	0.00e+00	976.00
IUUC-Kpa-049132	Komagataella pastoris	29.44	2.00e-42	167.00
IUUC-Lch-050040	Latimeria chalumnae	67.50	0.00e+00	892.00
IUUC-Lpe-050772	Leersia perrieri	30.73	1.00e-18	87.80
IUUC-Loc-052449	Lepisosteus oculatus	72.51	0.00e+00	681.00
IUUC-Lma-053248	Leptosphaeria maculans	35.28	2.00e-52	201.00
IUUC-Laf-054121	Loxodonta africana	86.13	0.00e+00	1294.00
IUUC-Mcc-055514	Macaca mulatta	97.60	0.00e+00	1488.00
IUUC-Meu-056873	Macropus eugenii	70.64	0.00e+00	790.00
IUUC-Mor-057243	Magnaporthe oryzae	32.91	5.00e-53	203.00
IUUC-Mpo-057439	Magnaporthe poae	34.30	3.00e-55	210.00
IUUC-Mtr-058457	Medicago truncatula	32.05	1.00e-50	193.00
IUUC-Mla-058929	Melampsora laricipopulina	30.36	2.00e-50	193.00
IUUC-Mga-060157	Meleagris gallopavo	74.81	0.00e+00	1102.00
IUUC-Mvi-060442	Microbotryum violaceum	32.70	5.00e-49	190.00
IUUC-Mmr-061062	Microcebus murinus	90.39	0.00e+00	1422.00
IUUC-Mdo-062798	Monodelphis domestica	79.72	0.00e+00	1174.00
IUUC-Mmu-064050	Mus musculus	80.98	0.00e+00	1238.00
IUUC-Mac-065619	Musa acuminata	33.25	4.00e-48	185.00
IUUC-Mpu-066554	Mustela putorius furo	86.00	0.00e+00	1269.00
IUUC-Mlu-068003	Myotis lucifugus	84.84	0.00e+00	1288.00
IUUC-Nfi-068612	Neosartorya fischeri	33.40	4.00e-58	219.00
IUUC-Ncr-068878	Neurospora crassa	34.11	3.00e-46	180.00
IUUC-Nle-069661	Nomascus leucogenys	96.49	0.00e+00	1485.00
IUUC-Opr-070944	Ochotona princeps	72.40	8.00e-158	550.00
IUUC-Ont-071266	Oreochromis niloticus	56.76	0.00e+00	769.00
IUUC-Oan-073442	Ornithorhynchus anatinus	78.00	0.00e+00	1095.00
IUUC-Ocu-073788	Oryctolagus cuniculus	77.48	0.00e+00	1093.00
IUUC-Oba-075085	Oryza barthii	32.01	5.00e-33	134.00
IUUC-Obr-076663	Oryza brachyantha	31.38	3.00e-40	160.00
IUUC-Ogl-076937	Oryza glaberrima	29.04	4.00e-43	169.00
IUUC-Ogu-078909	Oryza glumaepatula	29.62	2.00e-41	164.00
IUUC-Oin-079617	Oryza indica	29.60	2.00e-42	167.00
IUUC-Olo-081043	Oryza longistaminata	26.46	9.00e-26	111.00
IUUC-Ome-081646	Oryza meridionalis	25.61	3.00e-25	110.00
IUUC-Oni-082914	Oryza nivara	29.20	2.00e-41	164.00
IUUC-Oru-084878	Oryza rufipogon	29.20	2.00e-41	164.00
IUUC-Osa-085822	Oryza sativa	29.90	3.00e-45	176.00
IUUC-Ola-086931	Oryzias latipes	55.61	0.00e+00	749.00
IUUC-Oga-088443	Otolemur garnettii	90.03	0.00e+00	1400.00
IUUC-Oar-089325	Ovis aries	82.60	0.00e+00	1153.00
IUUC-Ptr-091584	Pan troglodytes	92.86	0.00e+00	1411.00
IUUC-Psi-093366	Pelodiscus sinensis	74.24	0.00e+00	694.00
IUUC-Pno-095136	Phaeosphaeria nodorum	33.88	1.00e-46	181.00
IUUC-Ppa-095574	Physcomitrella patens	35.31	2.00e-53	203.00
IUUC-Pfo-097462	Poecilia formosa	74.68	0.00e+00	663.00
IUUC-Pab-098547	Pongo abelii	96.37	0.00e+00	1482.00
IUUC-Pop-099529	Populus trichocarpa	35.28	3.00e-55	209.00
IUUC-Pca-101066	Procavia capensis	77.47	0.00e+00	1146.00
IUUC-Ppe-102110	Prunus persica	34.10	4.00e-52	198.00
IUUC-Pva-103015	Pteropus vampyrus	81.23	0.00e+00	1219.00
IUUC-Ptt-103998	Puccinia triticina	31.80	2.00e-48	187.00
IUUC-Pte-104417	Pyrenophora teres	32.49	3.00e-49	190.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	33.67	2.00e-49	191.00
IUUC-Rno-105533	Rattus norvegicus	81.75	0.00e+00	1235.00
IUUC-Sce-106160	Saccharomyces cerevisiae	27.47	6.00e-35	142.00
IUUC-Sha-106590	Sarcophilus harrisii	78.60	0.00e+00	1178.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	34.39	3.00e-51	196.00
IUUC-Spo-108353	Schizosaccharomyces pombe	35.32	1.00e-57	217.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	34.95	6.00e-53	202.00
IUUC-Smo-108842	Selaginella moellendorffii	34.41	4.00e-33	134.00
IUUC-Sit-110781	Setaria italica	30.61	7.00e-50	192.00
IUUC-Sly-111797	Solanum lycopersicum	32.74	2.00e-49	190.00
IUUC-Stu-112188	Solanum tuberosum	33.76	6.00e-51	195.00
IUUC-Sbi-114862	Sorghum bicolor	30.85	1.00e-39	157.00
IUUC-Sre-115162	Sporisorium reilianum	33.48	2.00e-61	230.00
IUUC-Ssc-115505	Sus scrofa	91.26	4.00e-155	540.00
IUUC-Tgu-116535	Taeniopygia guttata	74.40	0.00e+00	1070.00
IUUC-Tru-117542	Takifugu rubripes	55.38	0.00e+00	776.00
IUUC-Tni-120200	Tetraodon nigroviridis	56.68	0.00e+00	774.00
IUUC-Tca-121548	Theobroma cacao	33.65	1.00e-38	154.00
IUUC-Tre-122124	Trichoderma reesei	32.63	4.00e-56	213.00
IUUC-Tvi-122457	Trichoderma virens	33.24	1.00e-48	188.00
IUUC-Tae-125646	Triticum aestivum	32.41	7.00e-49	188.00
IUUC-Tme-127180	Tuber melanosporum	37.47	4.00e-62	233.00
IUUC-Tbe-127530	Tupaia belangeri	73.03	0.00e+00	1014.00
IUUC-Ttr-128549	Tursiops truncatus	78.20	0.00e+00	1155.00
IUUC-Uma-129381	Ustilago maydis	32.54	2.00e-59	224.00
IUUC-Vda-129889	Verticillium dahliae	30.79	1.00e-46	182.00
IUUC-Vpa-130100	Vicugna pacos	80.10	0.00e+00	1178.00
IUUC-Vvi-131366	Vitis vinifera	34.86	3.00e-57	216.00
IUUC-Xtr-132048	Xenopus tropicalis	61.59	0.00e+00	870.00
IUUC-Xma-133593	Xiphophorus maculatus	75.16	0.00e+00	660.00
IUUC-Yli-134338	Yarrowia lipolytica	30.42	2.00e-28	121.00
IUUC-Zma-135586	Zea mays	29.84	9.00e-43	168.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence