iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	79.20	0.00e+00	1640.00	IUUC-Hsa-045964
E3 activity/RING/RING	77.26	0.00e+00	1615.00	IUUC-Mmu-064297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sorex araneus

Protein Sequence
(Fasta)

MAVSLPPTLA LSPPPDEIQH PYLKFSEWKF KLFRVRSLEK APEEAPVEKN ASSEEKLSLQ 60
KSLTAPDKAE GLKPAPTQPA LKPQPKFLKK SHGHGKARDK AIHQANLRQL CRICGNSFKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGTCT CTTTGCCACC CACCCTGGCA CTCAGTCCTC CCCCTGATGA AATCCAGCAC 60
CCATACCTTA AATTTTCAGA GTGGAAATTT AAGCTCTTCA GGGTGAGATC TTTGGAAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Interpro

IPR024627--RAG1

Pfam

PF12940--RAG1

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002250--P:adaptive immune response
GO:0010390--P:histone monoubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0045582--P:positive regulation of T cell differentiation
GO:0002331--P:pre-B cell allelic exclusion
GO:0051865--P:protein autoubiquitination
GO:0033077--P:T cell differentiation in thymus
GO:0043029--P:T cell homeostasis
GO:0048538--P:thymus development
GO:0033151--P:V(D)J recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001206	Ailuropoda melanoleuca	78.64	0.00e+00	1644.00
IUUC-Apl-003271	Anas platyrhynchos	67.08	0.00e+00	1415.00
IUUC-Aca-004400	Anolis carolinensis	66.00	0.00e+00	1402.00
IUUC-Ani-009488	Aspergillus nidulans	47.27	2.00e-09	56.20
IUUC-Ame-011295	Astyanax mexicanus	54.19	0.00e+00	1062.00
IUUC-Bgr-012178	Blumeria graminis	44.83	2.00e-08	52.40
IUUC-Bta-012421	Bos taurus	79.33	0.00e+00	1639.00
IUUC-Cja-019891	Callithrix jacchus	78.35	0.00e+00	1612.00
IUUC-Cfa-020740	Canis familiaris	74.90	0.00e+00	1565.00
IUUC-Cpo-021800	Cavia porcellus	77.48	0.00e+00	1546.00
IUUC-Csa-024203	Chlorocebus sabaeus	76.65	0.00e+00	1414.00
IUUC-Dre-028416	Danio rerio	73.70	3.00e-166	578.00
IUUC-Dno-029101	Dasypus novemcinctus	78.35	0.00e+00	1608.00
IUUC-Eca-033385	Equus caballus	79.12	0.00e+00	1637.00
IUUC-Fca-036545	Felis catus	78.54	0.00e+00	1644.00
IUUC-Fal-037208	Ficedula albicollis	66.60	0.00e+00	1404.00
IUUC-Gmo-039622	Gadus morhua	73.45	3.00e-164	572.00
IUUC-Gga-041182	Gallus gallus	66.60	0.00e+00	1382.00
IUUC-Gac-041682	Gasterosteus aculeatus	72.58	3.00e-166	578.00
IUUC-Ggo-044510	Gorilla gorilla	79.21	0.00e+00	1644.00
IUUC-Hsa-045964	Homo sapiens	79.02	0.00e+00	1642.00
IUUC-Itr-048862	Ictidomys tridecemlineatus	77.87	0.00e+00	1608.00
IUUC-Lch-050041	Latimeria chalumnae	61.86	0.00e+00	1273.00
IUUC-Loc-052464	Lepisosteus oculatus	57.60	0.00e+00	1193.00
IUUC-Lma-053037	Leptosphaeria maculans	45.65	8.00e-09	54.70
IUUC-Laf-053544	Loxodonta africana	78.45	0.00e+00	1637.00
IUUC-Mcc-054867	Macaca mulatta	79.02	0.00e+00	1639.00
IUUC-Meu-055986	Macropus eugenii	69.89	0.00e+00	1316.00
IUUC-Mga-059262	Meleagris gallopavo	66.51	0.00e+00	1388.00
IUUC-Mdo-062686	Monodelphis domestica	71.23	0.00e+00	1524.00
IUUC-Mmu-064297	Mus musculus	77.39	0.00e+00	1642.00
IUUC-Mpu-066027	Mustela putorius furo	78.54	0.00e+00	1618.00
IUUC-Mlu-067885	Myotis lucifugus	79.69	0.00e+00	1657.00
IUUC-Nle-070073	Nomascus leucogenys	79.12	0.00e+00	1644.00
IUUC-Ont-071400	Oreochromis niloticus	74.21	3.00e-174	605.00
IUUC-Oan-072920	Ornithorhynchus anatinus	92.11	0.00e+00	696.00
IUUC-Ocu-074616	Oryctolagus cuniculus	77.78	0.00e+00	1601.00
IUUC-Ola-086828	Oryzias latipes	74.07	8.00e-173	600.00
IUUC-Oga-088675	Otolemur garnettii	90.16	1.00e-103	368.00
IUUC-Oar-090380	Ovis aries	78.35	0.00e+00	1629.00
IUUC-Ptr-090648	Pan troglodytes	79.21	0.00e+00	1645.00
IUUC-Pan-092036	Papio anubis	78.93	0.00e+00	1635.00
IUUC-Psi-093130	Pelodiscus sinensis	69.96	0.00e+00	1491.00
IUUC-Pfo-097273	Poecilia formosa	74.02	6.00e-166	577.00
IUUC-Pca-100134	Procavia capensis	73.49	0.00e+00	1513.00
IUUC-Pte-104362	Pyrenophora teres	45.65	5.00e-08	52.00
IUUC-Pyt-104823	Pyrenophora triticirepentis	41.18	3.00e-07	49.30
IUUC-Rno-105632	Rattus norvegicus	77.39	0.00e+00	1637.00
IUUC-Sha-107238	Sarcophilus harrisii	71.95	0.00e+00	1538.00
IUUC-Ssc-115720	Sus scrofa	79.02	0.00e+00	1631.00
IUUC-Tgu-117030	Taeniopygia guttata	66.80	0.00e+00	1396.00
IUUC-Tru-117669	Takifugu rubripes	53.61	0.00e+00	1016.00
IUUC-Tsy-119578	Tarsius syrichta	76.53	0.00e+00	1592.00
IUUC-Tni-120073	Tetraodon nigroviridis	75.71	1.00e-167	583.00
IUUC-Tbe-128029	Tupaia belangeri	78.42	0.00e+00	872.00
IUUC-Ttr-128677	Tursiops truncatus	88.37	0.00e+00	723.00
IUUC-Vpa-130346	Vicugna pacos	90.86	0.00e+00	696.00
IUUC-Xtr-132442	Xenopus tropicalis	86.62	2.00e-71	260.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence