iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001532

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01116223

Gene Name

UBE2E1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000003515.1	ENSAMET00000003852.1	ENSAMEP00000003704.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.30e-50	169.5	52	187

Active Site

Position(s)	Description	Evidence
132	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++++ dpp+++sa+p+ + +++ew+ +ilGp++++YeggvF l+i+f+++YPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 52   RIQKELADITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 137
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 138  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQ 187
           *********************************************99985 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

AMSDDDSRAS TSSSSSSSSN QQTEKETNTP KKKESKVSMS KNSKLLSTSA KRIQKELADI 60
TLDPPPNCSA GPKGDNIYEW RSTILGPPGS VYEGGVFFLD ITFTPEYPFK PPKVTFRTRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTATGTCGG ATGACGATTC GAGGGCCAGC ACCAGCTCCT CCTCATCTTC GTCCTCCAAC 60
CAGCAAACCG AGAAAGAAAC AAACACCCCC AAGAAGAAGG AGAGTAAAGT CAGCATGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0033523--P:histone H2B ubiquitination
GO:0010390--P:histone monoubiquitination
GO:0032020--P:ISG15-protein conjugation
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004207	Anas platyrhynchos	99.48	3.00e-93	333.00
IUUC-Aca-005103	Anolis carolinensis	99.43	2.00e-93	334.00
IUUC-Ame-011419	Astyanax mexicanus	95.10	1.00e-81	295.00
IUUC-Bta-012796	Bos taurus	93.71	4.00e-79	286.00
IUUC-Cja-019311	Callithrix jacchus	100.00	8.00e-94	335.00
IUUC-Cfa-020017	Canis familiaris	100.00	8.00e-94	335.00
IUUC-Cpo-022266	Cavia porcellus	100.00	8.00e-94	335.00
IUUC-Cre-022791	Chlamydomonas reinhardtii	80.41	2.00e-70	257.00
IUUC-Csa-023538	Chlorocebus sabaeus	100.00	8.00e-94	335.00
IUUC-Cho-024986	Choloepus hoffmanni	76.27	1.00e-74	272.00
IUUC-Cin-025161	Ciona intestinalis	84.38	1.00e-75	275.00
IUUC-Csv-025982	Ciona savignyi	84.38	3.00e-82	297.00
IUUC-Cme-027286	Cyanidioschyzon merolae	70.91	2.00e-69	254.00
IUUC-Dre-027449	Danio rerio	87.86	2.00e-83	301.00
IUUC-Dno-029441	Dasypus novemcinctus	100.00	4.00e-75	272.00
IUUC-Dor-030450	Dipodomys ordii	100.00	4.00e-64	235.00
IUUC-Dme-032042	Drosophila melanogaster	87.12	5.00e-83	300.00
IUUC-Ete-032397	Echinops telfairi	98.29	4.00e-101	359.00
IUUC-Eca-033312	Equus caballus	95.80	3.00e-82	297.00
IUUC-Eeu-034931	Erinaceus europaeus	86.29	8.00e-81	292.00
IUUC-Fca-035467	Felis catus	100.00	7.00e-94	335.00
IUUC-Fal-036907	Ficedula albicollis	99.43	2.00e-93	334.00
IUUC-Gmo-039645	Gadus morhua	87.86	8.00e-84	302.00
IUUC-Gga-040403	Gallus gallus	99.43	2.00e-93	334.00
IUUC-Gac-042007	Gasterosteus aculeatus	92.22	3.00e-80	290.00
IUUC-Ggo-045507	Gorilla gorilla	100.00	8.00e-94	335.00
IUUC-Hsa-046576	Homo sapiens	100.00	8.00e-94	335.00
IUUC-Itr-048197	Ictidomys tridecemlineatus	100.00	4.00e-75	272.00
IUUC-Lch-050322	Latimeria chalumnae	95.43	3.00e-98	350.00
IUUC-Loc-052673	Lepisosteus oculatus	89.14	4.00e-86	310.00
IUUC-Laf-054313	Loxodonta africana	100.00	8.00e-94	335.00
IUUC-Mcc-055072	Macaca mulatta	97.90	1.00e-83	301.00
IUUC-Meu-056590	Macropus eugenii	100.00	5.00e-85	305.00
IUUC-Mga-059436	Meleagris gallopavo	95.80	3.00e-82	297.00
IUUC-Mmr-060791	Microcebus murinus	100.00	8.00e-94	335.00
IUUC-Mdo-063010	Monodelphis domestica	95.80	3.00e-82	297.00
IUUC-Mmu-063297	Mus musculus	98.86	1.00e-102	365.00
IUUC-Mpu-065698	Mustela putorius furo	99.43	2.00e-103	367.00
IUUC-Mlu-067897	Myotis lucifugus	97.90	1.00e-83	301.00
IUUC-Nle-069622	Nomascus leucogenys	100.00	8.00e-94	335.00
IUUC-Opr-070917	Ochotona princeps	91.23	8.00e-58	214.00
IUUC-Ont-071689	Oreochromis niloticus	92.44	4.00e-92	330.00
IUUC-Oan-073006	Ornithorhynchus anatinus	100.00	5.00e-75	272.00
IUUC-Ocu-074055	Oryctolagus cuniculus	100.00	8.00e-94	335.00
IUUC-Ola-086636	Oryzias latipes	92.94	3.00e-83	300.00
IUUC-Olu-087783	Ostreococcus lucimarinus	75.71	9.00e-64	235.00
IUUC-Oga-088863	Otolemur garnettii	100.00	8.00e-94	335.00
IUUC-Oar-089803	Ovis aries	99.43	2.00e-103	367.00
IUUC-Ptr-090914	Pan troglodytes	100.00	8.00e-94	335.00
IUUC-Pan-092786	Papio anubis	100.00	8.00e-94	335.00
IUUC-Psi-093923	Pelodiscus sinensis	100.00	8.00e-94	335.00
IUUC-Pma-094642	Petromyzon marinus	95.24	4.00e-71	259.00
IUUC-Ppa-095789	Physcomitrella patens	76.67	2.00e-68	251.00
IUUC-Pfo-096966	Poecilia formosa	91.23	5.00e-83	300.00
IUUC-Pab-098614	Pongo abelii	100.00	8.00e-94	335.00
IUUC-Pop-099024	Populus trichocarpa	62.24	7.00e-56	209.00
IUUC-Pca-100467	Procavia capensis	95.80	3.00e-82	297.00
IUUC-Pva-102561	Pteropus vampyrus	97.90	1.00e-83	301.00
IUUC-Rno-105518	Rattus norvegicus	98.27	1.00e-100	358.00
IUUC-Sha-106897	Sarcophilus harrisii	100.00	9.00e-86	308.00
IUUC-Smo-108957	Selaginella moellendorffii	68.24	7.00e-61	225.00
IUUC-Sar-113672	Sorex araneus	95.80	3.00e-82	297.00
IUUC-Ssc-116298	Sus scrofa	97.96	5.00e-85	305.00
IUUC-Tgu-116958	Taeniopygia guttata	100.00	3.00e-89	320.00
IUUC-Tru-118531	Takifugu rubripes	93.71	2.00e-80	291.00
IUUC-Tsy-119046	Tarsius syrichta	95.80	5.00e-82	296.00
IUUC-Tni-120349	Tetraodon nigroviridis	94.51	6.00e-82	296.00
IUUC-Tca-121777	Theobroma cacao	59.72	3.00e-53	201.00
IUUC-Tbe-127690	Tupaia belangeri	95.80	5.00e-82	296.00
IUUC-Ttr-128356	Tursiops truncatus	96.57	8.00e-89	319.00
IUUC-Vpa-130232	Vicugna pacos	96.45	2.00e-79	288.00
IUUC-Xtr-132547	Xenopus tropicalis	100.00	6.00e-87	312.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence