iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028393

Ensembl Protein ID

ENSDARP00000045762.6

UniProt Accession

Q1ECZ2; Q1ECZ2_DANRE

Genbank Protein ID

AAI17614.1

Protein Name

Kelch-like ECH-associated protein 1a

Genbank Nucleotide ID

BX663525

Gene Name

keap1a; keap1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000016132.8	ENSDART00000045763.6	ENSDARP00000045762.6

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.70e-16	60.6	54	123
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.70e-11	40.9	157	188

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv...g.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +D +l+v   +  + f++hk+vLaasS++F+a+f+++++e +  ++v+++dv p+v + l++F Yt++++ 
   Q: 54   CDLVLHVtykDkIVDFKVHKLVLAASSPYFKAMFTSNFKECH-ASEVTLRDVCPQVISRLIDFAYTSRITV 123
           677777744314789**************************9.************************9976 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++N++gi rfA+  +c+dL+++ +++i++hF+
   Q: 157  PSNVIGISRFAEEIGCTDLHLRTREYINTHFN 188
           89*****************************6 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MICPRKKRPI KDEDFSAIVV PSMRGHGYLD YTVESHPSKA LQNMDELRHH EMLCDLVLHV 60
TYKDKIVDFK VHKLVLAASS PYFKAMFTSN FKECHASEVT LRDVCPQVIS RLIDFAYTSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGCGAGTA CGCGCCTGCT TCACAGTCAG TTGACAGCTG GAAGGCAGAG AAGCTTCGCG 60
CATAACAAAC TTTCGATTAT GTTTTTAGTT TTTTGCTTTG AGGTTTTACG CGCCAAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0071379--P:cellular response to prostaglandin stimulus
GO:0071466--P:cellular response to xenobiotic stimulus
GO:0016567--P:protein ubiquitination

KEGG

dre:321837

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ani-009157	Aspergillus nidulans	23.93	2.00e-05	43.10
IUUC-Ame-010991	Astyanax mexicanus	84.60	0.00e+00	1057.00
IUUC-Gmo-039500	Gadus morhua	76.69	0.00e+00	633.00
IUUC-Gac-042505	Gasterosteus aculeatus	77.39	0.00e+00	946.00
IUUC-Lch-049511	Latimeria chalumnae	66.95	0.00e+00	849.00
IUUC-Loc-052296	Lepisosteus oculatus	74.79	0.00e+00	930.00
IUUC-Ont-071456	Oreochromis niloticus	79.22	0.00e+00	961.00
IUUC-Ola-087065	Oryzias latipes	74.62	0.00e+00	902.00
IUUC-Pfo-096442	Poecilia formosa	75.00	0.00e+00	904.00
IUUC-Pyt-104490	Pyrenophora triticirepentis	28.05	2.00e-07	50.10
IUUC-Ssl-108429	Sclerotinia sclerotiorum	39.39	3.00e-07	49.30
IUUC-Tru-118677	Takifugu rubripes	77.23	0.00e+00	969.00
IUUC-Tni-119845	Tetraodon nigroviridis	76.37	0.00e+00	956.00
IUUC-Xtr-132297	Xenopus tropicalis	60.28	0.00e+00	721.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence