iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036645

Ensembl Protein ID

ENSFALP00000003514.1

UniProt Accession

U3JL60; U3JL60_FICAL

Genbank Protein ID

ENSFALP00000003514

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021885

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000003380.1	ENSFALT00000003528.1	ENSFALP00000003514.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-42	141.5	508	540
UBD/Beta-Prp	1.50e-66	224.2	271	545

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l f +d  l++s+s D++++vWD+r
   Q: 508  GHTDNITSLTFsPDsSLIASASMDNSVRVWDIR 540
           8***********999****************76 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +sp+++lla+g++++++k+w++++ kl                                ++ l gh ++v++++f +d++ l++
   Q: 271  LNTAEISPNSKLLAAGFDNSCVKLWSLRSRKLksephlvdvsrirlacdildeeeeeddntgteMKILRGHCGPVYSTRFLSDSSGLLS 359
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl++++ ++ ++gh + v++l++sp + +++sGshdrt+r+w  +  + l+ + +gh + v c+++hp++n++++Gs+D
   Q: 360  CSEDMSIRYWDLRSFTNTVLYQGHAYPVWDLDISPCSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCIKFHPNSNYIATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v  l+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+s+r
   Q: 448  KTVRLWSTQQGNSVRLFTG-HRGPVLALAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLIASASMDNSVR 535
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdll 257
           +Wd+r+  ++
   Q: 536  VWDIRNTYCN 545
           *****98876 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MKRVRTEQIQ MAVSCYLKRH QYVDSEGPLK QGLRLCQTAE EMAANLTVQS ESGCANVVSA 60
APCLAEPQQY EVQFGRLRNF LTDSDSQHSH EVMPLLYPLF VYLHLNMVQN GLKSTVDSFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAACGCG TACGCACAGA ACAGATTCAG ATGGCAGTGT CCTGCTACCT CAAGCGCCAT 60
CAGTATGTGG ACTCAGAAGG TCCCCTAAAA CAAGGGCTGA GGCTGTGTCA GACTGCTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	91.91	0.00e+00	993.00
IUUC-Apl-003636	Anas platyrhynchos	97.67	0.00e+00	1115.00
IUUC-Aca-004229	Anolis carolinensis	93.53	0.00e+00	1055.00
IUUC-Ame-010599	Astyanax mexicanus	68.59	0.00e+00	797.00
IUUC-Bta-013404	Bos taurus	87.59	0.00e+00	945.00
IUUC-Cja-019643	Callithrix jacchus	92.09	0.00e+00	1014.00
IUUC-Cfa-020913	Canis familiaris	92.27	0.00e+00	1014.00
IUUC-Cpo-021777	Cavia porcellus	90.29	0.00e+00	978.00
IUUC-Csa-024184	Chlorocebus sabaeus	92.09	0.00e+00	1016.00
IUUC-Cho-024638	Choloepus hoffmanni	92.27	0.00e+00	988.00
IUUC-Cin-025618	Ciona intestinalis	35.93	3.00e-88	319.00
IUUC-Csv-025874	Ciona savignyi	34.40	4.00e-85	308.00
IUUC-Dre-028817	Danio rerio	68.19	0.00e+00	779.00
IUUC-Dno-029969	Dasypus novemcinctus	84.71	0.00e+00	957.00
IUUC-Dor-031117	Dipodomys ordii	89.75	0.00e+00	994.00
IUUC-Ete-032712	Echinops telfairi	84.17	0.00e+00	886.00
IUUC-Eca-033742	Equus caballus	92.27	0.00e+00	1014.00
IUUC-Eeu-035096	Erinaceus europaeus	89.23	0.00e+00	1011.00
IUUC-Fca-035769	Felis catus	91.76	0.00e+00	1035.00
IUUC-Fso-038302	Fusarium solani	32.79	2.00e-39	157.00
IUUC-Gmo-038636	Gadus morhua	65.43	0.00e+00	743.00
IUUC-Gga-040144	Gallus gallus	97.66	0.00e+00	1089.00
IUUC-Gac-041716	Gasterosteus aculeatus	66.96	0.00e+00	766.00
IUUC-Ggo-044568	Gorilla gorilla	92.27	0.00e+00	1016.00
IUUC-Hsa-046178	Homo sapiens	92.27	0.00e+00	1016.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	85.61	0.00e+00	988.00
IUUC-Lch-050501	Latimeria chalumnae	80.18	0.00e+00	891.00
IUUC-Loc-052895	Lepisosteus oculatus	82.60	8.00e-172	596.00
IUUC-Laf-053950	Loxodonta africana	88.67	0.00e+00	966.00
IUUC-Mcc-055450	Macaca mulatta	92.09	0.00e+00	1012.00
IUUC-Meu-056182	Macropus eugenii	88.49	0.00e+00	964.00
IUUC-Mga-059619	Meleagris gallopavo	97.48	0.00e+00	1086.00
IUUC-Mmr-061074	Microcebus murinus	90.68	0.00e+00	1024.00
IUUC-Mdo-062307	Monodelphis domestica	93.12	0.00e+00	900.00
IUUC-Mmu-063226	Mus musculus	88.67	0.00e+00	964.00
IUUC-Mpu-066016	Mustela putorius furo	92.09	0.00e+00	994.00
IUUC-Mlu-067257	Myotis lucifugus	83.92	0.00e+00	977.00
IUUC-Nle-070139	Nomascus leucogenys	92.45	0.00e+00	1018.00
IUUC-Opr-070243	Ochotona princeps	88.13	0.00e+00	979.00
IUUC-Ont-072686	Oreochromis niloticus	69.01	0.00e+00	793.00
IUUC-Oan-073670	Ornithorhynchus anatinus	83.19	0.00e+00	796.00
IUUC-Ocu-074525	Oryctolagus cuniculus	91.55	0.00e+00	1018.00
IUUC-Ola-086524	Oryzias latipes	68.66	0.00e+00	813.00
IUUC-Oga-088540	Otolemur garnettii	92.45	0.00e+00	1016.00
IUUC-Oar-089793	Ovis aries	85.43	0.00e+00	892.00
IUUC-Ptr-091154	Pan troglodytes	92.27	0.00e+00	1016.00
IUUC-Pan-092759	Papio anubis	92.09	0.00e+00	1012.00
IUUC-Psi-094008	Pelodiscus sinensis	93.53	0.00e+00	1060.00
IUUC-Pma-094593	Petromyzon marinus	47.12	2.00e-131	462.00
IUUC-Pfo-097409	Poecilia formosa	66.96	0.00e+00	771.00
IUUC-Pab-097946	Pongo abelii	80.76	0.00e+00	867.00
IUUC-Pca-100727	Procavia capensis	84.89	0.00e+00	897.00
IUUC-Pva-103211	Pteropus vampyrus	81.83	0.00e+00	922.00
IUUC-Rno-105236	Rattus norvegicus	89.21	0.00e+00	954.00
IUUC-Sha-106833	Sarcophilus harrisii	93.20	0.00e+00	1034.00
IUUC-Sar-113381	Sorex araneus	92.45	0.00e+00	1045.00
IUUC-Ssc-116421	Sus scrofa	89.75	0.00e+00	1028.00
IUUC-Tgu-117143	Taeniopygia guttata	98.74	0.00e+00	1120.00
IUUC-Tru-118680	Takifugu rubripes	68.13	0.00e+00	794.00
IUUC-Tsy-119622	Tarsius syrichta	76.62	0.00e+00	758.00
IUUC-Tni-120131	Tetraodon nigroviridis	67.08	0.00e+00	791.00
IUUC-Tbe-127656	Tupaia belangeri	88.64	1.00e-82	300.00
IUUC-Ttr-129171	Tursiops truncatus	89.21	0.00e+00	966.00
IUUC-Xtr-132241	Xenopus tropicalis	82.76	0.00e+00	924.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence