iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074525

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02026172

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000010697.3	ENSOCUT00000010695.3	ENSOCUP00000009211.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-41	139.1	510	542
UBD/Beta-Prp	4.50e-69	232.9	273	567

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l f +d +l++s+s D++++vWD+r
   Q: 510  GHTDNITSLTFsPDsGLIASASMDNSVRVWDIR 542
           8***********999****************76 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +spd++lla+g+++++ik+w+++++kl                                ++ l gh ++v++++f  d++ l++
   Q: 273  LNTAEISPDSKLLAAGFDNSCIKLWSLRSKKLksephqvdvsrihlacdileeeddeddnagteMKILRGHCGPVYSTRFLADSSGLLS 361
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ti+ wdl +++ ++ ++gh + v++l++sp++ +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 362  CSEDMTIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTD 449
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+s+r
   Q: 450  KTVRLWSAQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLFKELRGHTDNITSLTFSPDSGLIASASMDNSVR 537
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdllktlqlhnssvisvavlsfgd 277
           +Wd+r+  + +   ++ s ++ v + ++++
   Q: 538  VWDIRNTYCSTPADGSSSELVGVYTGQMSN 567
           *****9999999999887776666644433 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MVMKRVRTEQ IQMAVSCYLK RRQYVDSDGP LKQGLRLSQT AEEMAANLTV QSESGCANIV 60
SATPCQAEPQ QYEVQFGRLR NFLTDSDSQH SHEVMPLLYP LFVYLHLNLV QNSPKSTVES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTCCCCAC TGAAGGGGAA AGGCAACCGG CGTCTCTGGG CGAAGTCGAG AGGAAACTTC 60
GCACATGGTG AGCGTGCGTG GGTGGGTACG GAGCCGACCT CTGTGAGTGA CGCGCGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR007582--TFIID_NTD2
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	97.62	0.00e+00	1108.00
IUUC-Apl-003636	Anas platyrhynchos	92.05	0.00e+00	1108.00
IUUC-Aca-004229	Anolis carolinensis	90.83	0.00e+00	1072.00
IUUC-Ame-010599	Astyanax mexicanus	67.05	0.00e+00	819.00
IUUC-Bta-013404	Bos taurus	92.70	0.00e+00	1052.00
IUUC-Cja-019643	Callithrix jacchus	98.47	0.00e+00	1123.00
IUUC-Cfa-020913	Canis familiaris	98.14	0.00e+00	1117.00
IUUC-Cpo-021777	Cavia porcellus	94.91	0.00e+00	1082.00
IUUC-Csa-024184	Chlorocebus sabaeus	98.47	0.00e+00	1123.00
IUUC-Cho-024638	Choloepus hoffmanni	97.11	0.00e+00	1096.00
IUUC-Cin-025618	Ciona intestinalis	35.13	3.00e-89	322.00
IUUC-Csv-025874	Ciona savignyi	42.31	6.00e-78	285.00
IUUC-Dre-028817	Danio rerio	67.11	0.00e+00	810.00
IUUC-Dno-029969	Dasypus novemcinctus	88.64	0.00e+00	1043.00
IUUC-Dor-031117	Dipodomys ordii	95.42	0.00e+00	1114.00
IUUC-Ete-032712	Echinops telfairi	89.30	0.00e+00	990.00
IUUC-Eca-033742	Equus caballus	97.79	0.00e+00	1112.00
IUUC-Eeu-035096	Erinaceus europaeus	95.08	0.00e+00	1120.00
IUUC-Fca-035769	Felis catus	96.79	0.00e+00	1130.00
IUUC-Fal-036645	Ficedula albicollis	91.55	0.00e+00	1044.00
IUUC-Gmo-038636	Gadus morhua	64.00	0.00e+00	777.00
IUUC-Gga-040144	Gallus gallus	91.85	0.00e+00	1079.00
IUUC-Gac-041716	Gasterosteus aculeatus	68.06	0.00e+00	813.00
IUUC-Ggo-044568	Gorilla gorilla	98.64	0.00e+00	1124.00
IUUC-Hsa-046178	Homo sapiens	98.64	0.00e+00	1124.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	89.47	0.00e+00	1079.00
IUUC-Lch-050501	Latimeria chalumnae	78.01	0.00e+00	865.00
IUUC-Loc-052895	Lepisosteus oculatus	83.42	0.00e+00	648.00
IUUC-Laf-053950	Loxodonta africana	92.87	0.00e+00	1068.00
IUUC-Mcc-055450	Macaca mulatta	98.47	0.00e+00	1120.00
IUUC-Meu-056182	Macropus eugenii	88.62	0.00e+00	1015.00
IUUC-Mga-059619	Meleagris gallopavo	92.02	0.00e+00	1082.00
IUUC-Mmr-061074	Microcebus murinus	96.79	0.00e+00	1128.00
IUUC-Mdo-062307	Monodelphis domestica	93.54	0.00e+00	893.00
IUUC-Mmu-063226	Mus musculus	92.70	0.00e+00	1054.00
IUUC-Mpu-066016	Mustela putorius furo	97.28	0.00e+00	1099.00
IUUC-Mlu-067257	Myotis lucifugus	87.48	0.00e+00	1075.00
IUUC-Nle-070139	Nomascus leucogenys	98.47	0.00e+00	1122.00
IUUC-Opr-070243	Ochotona princeps	94.06	0.00e+00	1100.00
IUUC-Ont-072686	Oreochromis niloticus	69.33	0.00e+00	833.00
IUUC-Oan-073670	Ornithorhynchus anatinus	82.49	0.00e+00	827.00
IUUC-Ola-086524	Oryzias latipes	68.50	0.00e+00	854.00
IUUC-Oga-088540	Otolemur garnettii	97.28	0.00e+00	1108.00
IUUC-Oar-089793	Ovis aries	89.32	0.00e+00	984.00
IUUC-Ptr-091154	Pan troglodytes	98.64	0.00e+00	1124.00
IUUC-Pan-092759	Papio anubis	98.47	0.00e+00	1120.00
IUUC-Psi-094008	Pelodiscus sinensis	88.79	0.00e+00	1068.00
IUUC-Pma-094593	Petromyzon marinus	46.23	5.00e-134	471.00
IUUC-Pfo-097409	Poecilia formosa	67.39	0.00e+00	810.00
IUUC-Pab-097946	Pongo abelii	86.59	0.00e+00	963.00
IUUC-Pca-100727	Procavia capensis	89.30	0.00e+00	996.00
IUUC-Pva-103211	Pteropus vampyrus	83.70	0.00e+00	1008.00
IUUC-Ptt-103995	Puccinia triticina	44.14	1.00e-70	261.00
IUUC-Rno-105236	Rattus norvegicus	93.21	0.00e+00	1055.00
IUUC-Sha-106833	Sarcophilus harrisii	93.24	0.00e+00	1087.00
IUUC-Sar-113381	Sorex araneus	97.62	0.00e+00	1143.00
IUUC-Ssc-116421	Sus scrofa	94.40	0.00e+00	1131.00
IUUC-Tgu-117143	Taeniopygia guttata	92.53	0.00e+00	1114.00
IUUC-Tru-118680	Takifugu rubripes	67.67	0.00e+00	836.00
IUUC-Tsy-119622	Tarsius syrichta	82.17	0.00e+00	859.00
IUUC-Tni-120131	Tetraodon nigroviridis	67.83	0.00e+00	841.00
IUUC-Ttr-129171	Tursiops truncatus	93.55	0.00e+00	1067.00
IUUC-Xtr-132241	Xenopus tropicalis	81.02	0.00e+00	956.00
IUUC-Xma-133554	Xiphophorus maculatus	68.16	0.00e+00	749.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence