iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-070153

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01178052

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000005343.2	ENSNLET00000006818.2	ENSNLEP00000006490.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.50e-83	280.0	445	949

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 445  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 522
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    +++++ +e  e ++++l++         +  ++   +k+li+++F+g+l+++i+cl+c+++s++ e
   Q: 523  QDCSEYLRFLLDRLHEEEKIlkvQSSHKPSEILECSETSLQEVaskaavltETPRTSDGEKTLIEKMFGGKLQTHIRCLNCRSTSQKVE 611
           *****************95577777888888888888888888888999988888888999**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  +++ ++                                                                        
   Q: 612  AFTDLSLAFCPSSSLENMsfqdpasspstqdgglmqaavpgpseepvvynpttaaficdsvvnertigsppnefycsentsvrnesnki 700
           *********9999776669********************************************************************** PP
   S: 186  ................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple 258
                           s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl 
   Q: 701  lvnkdvpqkpggettpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLV 789
           ***************************************************************************************** PP
   S: 259  Ldlspfcts...............................peekqkekkkYeLiavvvHsG.slssGHYvayvkn.............. 301
           L+l    t+                               +e + ++ + Y L++vvvHsG s++sGHY++y++n              
   Q: 790  LELPVKRTTsfsslseswsvdvdftdlsenlakklkpsgtDEASCTKLVPYLLSSVVVHSGvSSESGHYYSYARNitstdssyqmyhqs 878
           999964444466677777777777777777777776666644444559***************************************** PP
   S: 302  ..............................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                          +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 879  ealalassqshllgrdspsavfeqdlenkeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 949
           ******9999999999999999988865544555*******************999************986 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MDKILEGLVS SSHPLPLKRV IVRKVVESAE HWLDKAQCEA MFDLTTRLIL EGQDPFQRQV 60
GHQVLEAYAR YHRPEFESFF NKTFVLGLLH QGYHSLDRRD VAILDYIHNG LKLIMSCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCCTAGGT CCTTCACTTC CTGTTTGCCG GCACTTCAAT ATCCGGGTCA AAGGGTGTCG 60
CTTCGGTCTC TTCTCCCCGG CTGATCCCAG AACCCTCCGT GACAGCGCGT CCTGACTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

nle:100600209

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	92.64	0.00e+00	1842.00
IUUC-Apl-003435	Anas platyrhynchos	75.80	0.00e+00	1251.00
IUUC-Aca-004556	Anolis carolinensis	70.32	0.00e+00	1263.00
IUUC-Ame-010616	Astyanax mexicanus	62.34	0.00e+00	1197.00
IUUC-Bta-013544	Bos taurus	92.23	0.00e+00	1807.00
IUUC-Cja-018745	Callithrix jacchus	94.17	0.00e+00	1881.00
IUUC-Cfa-020434	Canis familiaris	89.16	0.00e+00	1773.00
IUUC-Cpo-021666	Cavia porcellus	91.65	0.00e+00	1776.00
IUUC-Csa-023965	Chlorocebus sabaeus	97.70	0.00e+00	1999.00
IUUC-Cho-024809	Choloepus hoffmanni	83.86	0.00e+00	1249.00
IUUC-Cin-025604	Ciona intestinalis	29.59	5.00e-38	151.00
IUUC-Csv-026333	Ciona savignyi	43.68	1.00e-31	129.00
IUUC-Dre-028338	Danio rerio	62.52	0.00e+00	1216.00
IUUC-Dno-029372	Dasypus novemcinctus	91.27	0.00e+00	1824.00
IUUC-Dor-030752	Dipodomys ordii	89.47	0.00e+00	1240.00
IUUC-Dme-031871	Drosophila melanogaster	33.63	6.00e-43	169.00
IUUC-Ete-032588	Echinops telfairi	79.61	0.00e+00	1105.00
IUUC-Eca-034416	Equus caballus	93.86	0.00e+00	1908.00
IUUC-Eeu-035132	Erinaceus europaeus	73.85	0.00e+00	1370.00
IUUC-Fca-036137	Felis catus	92.90	0.00e+00	1858.00
IUUC-Fal-037297	Ficedula albicollis	75.50	0.00e+00	1431.00
IUUC-Gmo-038727	Gadus morhua	66.16	0.00e+00	1016.00
IUUC-Gga-041091	Gallus gallus	73.45	0.00e+00	1379.00
IUUC-Gac-042082	Gasterosteus aculeatus	63.15	0.00e+00	1126.00
IUUC-Ggo-045376	Gorilla gorilla	93.21	0.00e+00	1827.00
IUUC-Hsa-046444	Homo sapiens	98.27	0.00e+00	1973.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	92.90	0.00e+00	1872.00
IUUC-Lch-050500	Latimeria chalumnae	71.41	0.00e+00	1392.00
IUUC-Loc-052625	Lepisosteus oculatus	64.42	0.00e+00	1264.00
IUUC-Laf-053689	Loxodonta africana	92.69	0.00e+00	1847.00
IUUC-Mcc-055286	Macaca mulatta	97.79	0.00e+00	1959.00
IUUC-Meu-056906	Macropus eugenii	49.85	0.00e+00	652.00
IUUC-Mga-059905	Meleagris gallopavo	73.57	0.00e+00	1212.00
IUUC-Mmr-061397	Microcebus murinus	95.01	0.00e+00	1900.00
IUUC-Mdo-062833	Monodelphis domestica	85.74	0.00e+00	1759.00
IUUC-Mmu-063157	Mus musculus	89.64	0.00e+00	1807.00
IUUC-Mpu-066434	Mustela putorius furo	93.47	0.00e+00	1880.00
IUUC-Mlu-068178	Myotis lucifugus	91.31	0.00e+00	1793.00
IUUC-Opr-070454	Ochotona princeps	43.71	2.00e-67	250.00
IUUC-Ont-072330	Oreochromis niloticus	62.63	0.00e+00	1204.00
IUUC-Oan-072709	Ornithorhynchus anatinus	80.29	0.00e+00	1258.00
IUUC-Ocu-074832	Oryctolagus cuniculus	94.05	0.00e+00	1887.00
IUUC-Ola-087003	Oryzias latipes	54.12	5.00e-44	170.00
IUUC-Oga-088517	Otolemur garnettii	89.97	0.00e+00	1789.00
IUUC-Oar-089472	Ovis aries	88.58	0.00e+00	1734.00
IUUC-Ptr-090996	Pan troglodytes	97.89	0.00e+00	1966.00
IUUC-Pan-091837	Papio anubis	95.61	0.00e+00	1942.00
IUUC-Psi-093236	Pelodiscus sinensis	76.12	0.00e+00	1150.00
IUUC-Pma-094349	Petromyzon marinus	52.85	0.00e+00	951.00
IUUC-Pfo-097193	Poecilia formosa	61.60	0.00e+00	1150.00
IUUC-Pab-098710	Pongo abelii	97.98	0.00e+00	1987.00
IUUC-Pca-100794	Procavia capensis	81.40	0.00e+00	1602.00
IUUC-Pva-102722	Pteropus vampyrus	92.43	0.00e+00	1857.00
IUUC-Rno-105743	Rattus norvegicus	88.87	0.00e+00	1769.00
IUUC-Sha-106563	Sarcophilus harrisii	84.91	0.00e+00	1420.00
IUUC-Sar-113533	Sorex araneus	76.87	0.00e+00	1514.00
IUUC-Ssc-116259	Sus scrofa	83.27	0.00e+00	1566.00
IUUC-Tgu-117475	Taeniopygia guttata	75.47	0.00e+00	1300.00
IUUC-Tru-118623	Takifugu rubripes	62.55	0.00e+00	1144.00
IUUC-Tsy-119250	Tarsius syrichta	93.12	0.00e+00	1466.00
IUUC-Tni-120441	Tetraodon nigroviridis	58.80	0.00e+00	1059.00
IUUC-Tbe-127936	Tupaia belangeri	79.94	0.00e+00	1527.00
IUUC-Ttr-128483	Tursiops truncatus	80.61	0.00e+00	1404.00
IUUC-Vpa-130303	Vicugna pacos	96.44	0.00e+00	1059.00
IUUC-Xtr-132773	Xenopus tropicalis	72.29	0.00e+00	1378.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence