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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063480
UUCD1 version UUC-MuM-01232
Ensembl Protein ID ENSMUSP00000022356.4
UniProt Accession Q8BL06; Q149D8; Q149D9; Q6NZE1; Q8BZ28; Q9D2I9; UBP54_MOUSE
Genbank Protein ID BAB31805.1; BAC29609.1; BAC33102.1; AAH66166.1; AAH66175.1; AAI17845.1; AAI17846.1
Protein Name Inactive ubiquitin carboxyl-terminal hydrolase 54; Inactive ubiquitin-specific peptidase 54
Genbank Nucleotide ID AK019588; AK036864; AK047620; AC146594; BC066175; BC117844; BC117845
Gene Name Usp54
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000034235.16 ENSMUST00000022356.10 ENSMUSP00000022356.4
ENSMUSG00000034235.16 ENSMUST00000123287.1 ENSMUSP00000117503.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.90e-24 86.3 32 349
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavspre.....llkalkkeaee 83
           Gl+N   +N+C++NS+LQ+L+++  +r+ + + +++k+  +       ++ ++l+ +f++++ +++++v p++     l k++++e+ +
   Q: 32   GLSNEpgQNSCFLNSALQVLWHLDIFRRSFRQLTTHKCMGD------SCIFCALKGIFNQFQ-CSSEKVLPSDtlrsaLAKTFQDEQ-R 112
           88887668******************************986......59************5.555555555543333555555444.5 PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           f+     Da E+++ ll +++ ++                    de +e+  + ++++ ++ F ++l +q++c +c+ +s    pf+++
   Q: 113  FQLGIMDDAAECFENLLMRIHFHI-------------------ADETKEDICTAQHCISHQKFAMTLFEQCVCSSCGATSDPL-PFIQM 181
           99**********************...................3455677899*************************99766.9**** PP
   S: 173  slpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
              ++    +++             +++ +  ++ +  g+ +   ++c ++    +++   + P+++++ L +   se+ +  e +  +
   Q: 182  VHYISTTALCNQAicmlekrekPSPSMFGELLQNASTMGDLRNCPSNCGERI-RIRRVL-MNAPQIITIGLVWD--SEHSDLAEDVIHS 266
           *****88877777888888887555566666666666666656777777766.466655.566**********9..5555566555555 PP
   S: 253  vefpleLdlsp..fctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvl 333
           + +   L+l    f ++ ++  k+++ Y L+++++++G     HY ++  ++k + W++fdD +V+e+  k+++v++++     ++ +l
   Q: 267  LGTC--LKLGDlfFRVT-DDRAKQSELY-LVGMICYYG----KHYSTFFFQTKIRkWMYFDDAHVKEIgpKWKDVVTKCIkghYQPLLL 347
           5554..55555213333.3333335555.*********....9*****99987767************766899988665555566666 PP
   S: 334  fY 335
           +Y
   Q: 348  LY 349
           66 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Has no peptidase activity.
 Has no peptidase activity.
Protein Sequence
(Fasta)
MSWKRNYFSG SRGSVQGMFA PRSSMSIAPS KGLSNEPGQN SCFLNSALQV LWHLDIFRRS 60
FRQLTTHKCM GDSCIFCALK GIFNQFQCSS EKVLPSDTLR SALAKTFQDE QRFQLGIMDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063480|DUB,USP|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTGCCCCACA GATGCCCTTG TGAGTGCTTG CAGTTTTTTC CTGAGCTCGA ATGGGTTGTC 60
TGGTAAGCAT TGTAGTTGTA TTAAAACTGT GTAGAGGGAG GATACCATGA CTGAGTAGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063480|DUB,USP|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0488--Methylation
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom
PROSITE

PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
KEGG mmu:78787
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000820 Aegilops tauschii 31.78 3.00e-18 86.30
IUUC-Aml-001414 Ailuropoda melanoleuca 71.70 0.00e+00 1428.00
IUUC-Atr-002451 Amborella trichopoda 31.29 2.00e-38 155.00
IUUC-Apl-004044 Anas platyrhynchos 91.50 1.00e-180 626.00
IUUC-Aca-004351 Anolis carolinensis 92.41 0.00e+00 774.00
IUUC-Aly-005468 Arabidopsis lyrata 32.78 7.00e-43 170.00
IUUC-Ath-007147 Arabidopsis thaliana 32.94 2.00e-42 168.00
IUUC-Ame-011525 Astyanax mexicanus 83.51 0.00e+00 711.00
IUUC-Bta-013344 Bos taurus 68.80 0.00e+00 1377.00
IUUC-Bdi-015058 Brachypodium distachyon 31.86 5.00e-41 164.00
IUUC-Bol-015670 Brassica oleracea 32.07 8.00e-40 159.00
IUUC-Bra-016731 Brassica rapa 32.65 5.00e-42 167.00
IUUC-Cja-018724 Callithrix jacchus 70.85 0.00e+00 1372.00
IUUC-Cfa-021222 Canis familiaris 71.00 0.00e+00 1481.00
IUUC-Cpo-021795 Cavia porcellus 71.82 0.00e+00 1059.00
IUUC-Cre-022697 Chlamydomonas reinhardtii 23.51 8.00e-17 84.30
IUUC-Csa-023262 Chlorocebus sabaeus 70.36 0.00e+00 1405.00
IUUC-Cho-024422 Choloepus hoffmanni 70.56 0.00e+00 1046.00
IUUC-Cin-025752 Ciona intestinalis 69.42 4.00e-48 183.00
IUUC-Csv-026063 Ciona savignyi 56.40 4.00e-112 397.00
IUUC-Dre-028802 Danio rerio 63.29 0.00e+00 826.00
IUUC-Dno-029417 Dasypus novemcinctus 71.41 0.00e+00 1441.00
IUUC-Dor-030653 Dipodomys ordii 64.60 0.00e+00 845.00
IUUC-Dme-032071 Drosophila melanogaster 54.74 3.00e-105 377.00
IUUC-Ete-032692 Echinops telfairi 56.78 2.00e-180 625.00
IUUC-Eca-033235 Equus caballus 71.86 0.00e+00 1110.00
IUUC-Eeu-034975 Erinaceus europaeus 57.33 0.00e+00 744.00
IUUC-Fca-036070 Felis catus 69.75 0.00e+00 1415.00
IUUC-Fal-037089 Ficedula albicollis 91.62 0.00e+00 779.00
IUUC-Gmo-038653 Gadus morhua 74.14 1.00e-169 589.00
IUUC-Gga-041241 Gallus gallus 91.36 0.00e+00 774.00
IUUC-Gac-042157 Gasterosteus aculeatus 74.32 0.00e+00 713.00
IUUC-Gma-043273 Glycine max 31.49 3.00e-38 154.00
IUUC-Ggo-045626 Gorilla gorilla 70.66 0.00e+00 1395.00
IUUC-Hsa-045767 Homo sapiens 71.05 0.00e+00 1402.00
IUUC-Hvu-047657 Hordeum vulgare 31.11 7.00e-42 166.00
IUUC-Itr-048187 Ictidomys tridecemlineatus 77.91 0.00e+00 2273.00
IUUC-Lch-049712 Latimeria chalumnae 86.65 0.00e+00 702.00
IUUC-Lpe-051572 Leersia perrieri 31.75 1.00e-38 156.00
IUUC-Loc-052615 Lepisosteus oculatus 60.86 0.00e+00 899.00
IUUC-Laf-054578 Loxodonta africana 77.39 0.00e+00 2153.00
IUUC-Mcc-054696 Macaca mulatta 70.52 0.00e+00 1378.00
IUUC-Meu-056841 Macropus eugenii 44.55 3.00e-137 483.00
IUUC-Mtr-058682 Medicago truncatula 29.39 2.00e-33 139.00
IUUC-Mga-059519 Meleagris gallopavo 45.05 0.00e+00 645.00
IUUC-Mmr-060701 Microcebus murinus 70.21 0.00e+00 1329.00
IUUC-Mdo-062433 Monodelphis domestica 52.59 0.00e+00 922.00
IUUC-Mac-064469 Musa acuminata 31.35 1.00e-18 89.70
IUUC-Mpu-066404 Mustela putorius furo 70.72 0.00e+00 1499.00
IUUC-Mlu-067841 Myotis lucifugus 77.79 0.00e+00 2123.00
IUUC-Nle-070110 Nomascus leucogenys 72.15 0.00e+00 1089.00
IUUC-Opr-070676 Ochotona princeps 74.10 0.00e+00 748.00
IUUC-Ont-072289 Oreochromis niloticus 81.17 0.00e+00 671.00
IUUC-Oan-073551 Ornithorhynchus anatinus 93.72 0.00e+00 770.00
IUUC-Ocu-074729 Oryctolagus cuniculus 71.19 0.00e+00 1452.00
IUUC-Oba-075174 Oryza barthii 29.41 2.00e-33 139.00
IUUC-Obr-076268 Oryza brachyantha 32.65 3.00e-42 167.00
IUUC-Ogl-077138 Oryza glaberrima 31.76 4.00e-39 157.00
IUUC-Ogu-078705 Oryza glumaepatula 29.41 1.00e-33 139.00
IUUC-Oin-079125 Oryza indica 31.76 5.00e-39 157.00
IUUC-Olo-080872 Oryza longistaminata 29.41 9.00e-34 139.00
IUUC-Ome-081864 Oryza meridionalis 29.71 4.00e-33 138.00
IUUC-Oni-082109 Oryza nivara 29.41 1.00e-33 139.00
IUUC-Opu-083823 Oryza punctata 32.35 7.00e-40 160.00
IUUC-Oru-084310 Oryza rufipogon 29.41 1.00e-33 139.00
IUUC-Osa-085583 Oryza sativa 31.76 2.00e-38 153.00
IUUC-Ola-086742 Oryzias latipes 59.82 0.00e+00 791.00
IUUC-Oga-088920 Otolemur garnettii 74.79 0.00e+00 1140.00
IUUC-Oar-089644 Ovis aries 68.96 0.00e+00 1379.00
IUUC-Ptr-091530 Pan troglodytes 72.26 0.00e+00 1088.00
IUUC-Pan-092190 Papio anubis 96.60 0.00e+00 801.00
IUUC-Psi-094022 Pelodiscus sinensis 91.88 0.00e+00 775.00
IUUC-Pma-094745 Petromyzon marinus 60.16 4.00e-135 474.00
IUUC-Ppa-095930 Physcomitrella patens 29.89 4.00e-39 158.00
IUUC-Pfo-096072 Poecilia formosa 81.17 0.00e+00 676.00
IUUC-Pab-097979 Pongo abelii 72.41 0.00e+00 1018.00
IUUC-Pop-099539 Populus trichocarpa 32.27 2.00e-38 155.00
IUUC-Pca-101005 Procavia capensis 61.59 0.00e+00 1114.00
IUUC-Ppe-101918 Prunus persica 31.20 2.00e-39 158.00
IUUC-Pva-103125 Pteropus vampyrus 71.57 0.00e+00 1393.00
IUUC-Rno-105463 Rattus norvegicus 87.70 0.00e+00 1908.00
IUUC-Sha-107164 Sarcophilus harrisii 52.06 0.00e+00 864.00
IUUC-Sit-110021 Setaria italica 31.96 2.00e-37 152.00
IUUC-Sly-110975 Solanum lycopersicum 31.79 1.00e-39 159.00
IUUC-Stu-112904 Solanum tuberosum 31.18 2.00e-38 155.00
IUUC-Sar-113423 Sorex araneus 53.08 0.00e+00 667.00
IUUC-Sbi-114345 Sorghum bicolor 32.55 3.00e-41 164.00
IUUC-Ssc-116206 Sus scrofa 70.36 0.00e+00 1420.00
IUUC-Tgu-116521 Taeniopygia guttata 77.45 0.00e+00 1283.00
IUUC-Tru-118155 Takifugu rubripes 70.20 9.00e-172 596.00
IUUC-Tsy-118998 Tarsius syrichta 68.74 0.00e+00 1217.00
IUUC-Tni-120257 Tetraodon nigroviridis 79.34 0.00e+00 657.00
IUUC-Tca-121692 Theobroma cacao 32.16 1.00e-38 156.00
IUUC-Tae-125619 Triticum aestivum 31.67 1.00e-42 169.00
IUUC-Tur-126027 Triticum urartu 31.39 2.00e-42 168.00
IUUC-Ttr-128290 Tursiops truncatus 71.66 0.00e+00 1026.00
IUUC-Vpa-130213 Vicugna pacos 68.80 0.00e+00 1045.00
IUUC-Vvi-131652 Vitis vinifera 31.49 2.00e-39 158.00
IUUC-Xtr-131831 Xenopus tropicalis 89.53 0.00e+00 756.00
IUUC-Xma-133456 Xiphophorus maculatus 78.37 0.00e+00 654.00
Created Date 25-Jun-2017

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