iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001518

Ensembl Protein ID

ENSAMEP00000018543.1

UniProt Accession

G1MGQ9; G1MGQ9_AILME

Genbank Protein ID

ENSAMEP00000018543

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01056154

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000017535.1	ENSAMET00000019288.1	ENSAMEP00000018543.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	6.00e-51	172.0	15	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           ats+l+ ++dwe+il+icdli++ +++ak+a+ +++k++n+knphval+aL++++s+v+nCg+++h+eva+k+++eel+ellk+++e++
   Q: 15   ATSQLLLETDWESILQICDLIRQGDTQAKYAVSSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKELLKRQVEVN 103
           799************************************************************************************** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v++K+++li++Wa++++nep++++++++++ +k eG++fp
   Q: 104  VRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP 143
           ***************************************8 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

RGVGSGTGVA MGHKATSQLL LETDWESILQ ICDLIRQGDT QAKYAVSSIK KKVNDKNPHV 60
ALYALEVMES VVKNCGQTVH DEVANKQTME ELKELLKRQV EVNVRNKILY LIQAWAHAFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGGCGTCG GGTCGGGGAC CGGGGTCGCC ATGGGGCGCG NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNTGCCAG TCCAGGGCGC TGGGCGCGGG CCCCTACCCA ACTGGGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003662	Anas platyrhynchos	82.09	0.00e+00	960.00
IUUC-Aca-004940	Anolis carolinensis	81.17	0.00e+00	1129.00
IUUC-Ago-007931	Ashbya gossypii	30.33	9.00e-27	115.00
IUUC-Acl-008274	Aspergillus clavatus	32.09	2.00e-39	157.00
IUUC-Afl-008521	Aspergillus flavus	34.39	6.00e-41	162.00
IUUC-Afu-008774	Aspergillus fumigatus	32.64	4.00e-41	162.00
IUUC-Ani-009445	Aspergillus nidulans	33.60	2.00e-41	164.00
IUUC-Ang-009863	Aspergillus niger	33.60	1.00e-41	164.00
IUUC-Ate-010444	Aspergillus terreus	35.97	2.00e-42	167.00
IUUC-Ame-011111	Astyanax mexicanus	76.90	0.00e+00	900.00
IUUC-Bgr-012087	Blumeria graminis	34.69	5.00e-43	169.00
IUUC-Bta-012506	Bos taurus	88.61	0.00e+00	1149.00
IUUC-Bci-013782	Botrytis cinerea	32.25	1.00e-41	164.00
IUUC-Cel-018493	Caenorhabditis elegans	52.20	3.00e-65	243.00
IUUC-Cja-019998	Callithrix jacchus	83.97	0.00e+00	1041.00
IUUC-Cfa-020615	Canis familiaris	90.08	0.00e+00	1106.00
IUUC-Cpo-022019	Cavia porcellus	87.13	0.00e+00	1173.00
IUUC-Csa-023596	Chlorocebus sabaeus	87.13	0.00e+00	1040.00
IUUC-Cin-025488	Ciona intestinalis	46.22	1.00e-121	430.00
IUUC-Csv-025802	Ciona savignyi	48.56	1.00e-111	396.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	35.79	3.00e-40	159.00
IUUC-Cne-026847	Cryptococcus neoformans	34.22	1.00e-36	147.00
IUUC-Dre-028353	Danio rerio	75.73	0.00e+00	885.00
IUUC-Dno-029005	Dasypus novemcinctus	84.93	0.00e+00	1101.00
IUUC-Dor-030280	Dipodomys ordii	85.68	0.00e+00	1098.00
IUUC-Dse-031238	Dothistroma septosporum	39.50	8.00e-43	168.00
IUUC-Dme-031952	Drosophila melanogaster	46.12	4.00e-96	345.00
IUUC-Ete-032235	Echinops telfairi	94.52	2.00e-127	449.00
IUUC-Eca-033873	Equus caballus	91.33	0.00e+00	1170.00
IUUC-Eeu-034652	Erinaceus europaeus	93.82	1.00e-100	360.00
IUUC-Fca-036563	Felis catus	90.55	0.00e+00	1165.00
IUUC-Fal-036649	Ficedula albicollis	80.56	0.00e+00	1021.00
IUUC-Fox-037962	Fusarium oxysporum	33.71	2.00e-39	157.00
IUUC-Fso-038396	Fusarium solani	33.95	1.00e-39	158.00
IUUC-Gmo-039510	Gadus morhua	72.35	0.00e+00	908.00
IUUC-Ggr-039938	Gaeumannomyces graminis	32.78	2.00e-38	154.00
IUUC-Gga-040201	Gallus gallus	78.12	0.00e+00	1060.00
IUUC-Gac-041459	Gasterosteus aculeatus	73.88	0.00e+00	920.00
IUUC-Ggo-044573	Gorilla gorilla	88.79	0.00e+00	1137.00
IUUC-Hsa-046009	Homo sapiens	88.54	0.00e+00	1177.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	88.28	0.00e+00	1192.00
IUUC-Kpa-049327	Komagataella pastoris	30.26	7.00e-32	132.00
IUUC-Lch-049944	Latimeria chalumnae	73.61	4.00e-147	514.00
IUUC-Loc-051850	Lepisosteus oculatus	77.45	0.00e+00	985.00
IUUC-Lma-053252	Leptosphaeria maculans	35.50	3.00e-41	163.00
IUUC-Laf-053346	Loxodonta africana	81.58	0.00e+00	1002.00
IUUC-Mcc-055789	Macaca mulatta	87.15	0.00e+00	1102.00
IUUC-Meu-056329	Macropus eugenii	68.91	1.00e-156	546.00
IUUC-Mor-057205	Magnaporthe oryzae	33.22	1.00e-38	154.00
IUUC-Mpo-057295	Magnaporthe poae	33.44	3.00e-39	157.00
IUUC-Mla-058849	Melampsora laricipopulina	33.33	3.00e-31	130.00
IUUC-Mga-059361	Meleagris gallopavo	78.61	0.00e+00	1014.00
IUUC-Mvi-060561	Microbotryum violaceum	31.46	1.00e-37	151.00
IUUC-Mmr-061122	Microcebus murinus	90.84	0.00e+00	986.00
IUUC-Mdo-062171	Monodelphis domestica	86.06	0.00e+00	1155.00
IUUC-Mmu-063952	Mus musculus	87.88	0.00e+00	1225.00
IUUC-Mpu-065852	Mustela putorius furo	90.31	0.00e+00	1132.00
IUUC-Mlu-066996	Myotis lucifugus	82.22	3.00e-149	521.00
IUUC-Nfi-068539	Neosartorya fischeri	32.31	2.00e-41	164.00
IUUC-Ncr-068726	Neurospora crassa	39.46	7.00e-40	159.00
IUUC-Nle-070148	Nomascus leucogenys	83.10	0.00e+00	1009.00
IUUC-Opr-070833	Ochotona princeps	71.05	0.00e+00	784.00
IUUC-Ont-071261	Oreochromis niloticus	74.66	0.00e+00	926.00
IUUC-Oan-073684	Ornithorhynchus anatinus	68.55	3.00e-149	521.00
IUUC-Ola-087570	Oryzias latipes	72.11	0.00e+00	930.00
IUUC-Oga-089087	Otolemur garnettii	86.87	0.00e+00	1027.00
IUUC-Oar-089534	Ovis aries	88.61	0.00e+00	1147.00
IUUC-Ptr-091654	Pan troglodytes	83.44	0.00e+00	1026.00
IUUC-Pan-092652	Papio anubis	87.39	0.00e+00	1108.00
IUUC-Pno-095125	Phaeosphaeria nodorum	38.36	7.00e-42	165.00
IUUC-Pfo-096757	Poecilia formosa	74.53	0.00e+00	903.00
IUUC-Pab-097788	Pongo abelii	90.38	0.00e+00	794.00
IUUC-Pca-100145	Procavia capensis	75.64	0.00e+00	858.00
IUUC-Pva-102965	Pteropus vampyrus	85.29	0.00e+00	1085.00
IUUC-Pgr-103609	Puccinia graminis	34.69	7.00e-34	138.00
IUUC-Ptt-103865	Puccinia triticina	35.71	9.00e-35	142.00
IUUC-Pte-104095	Pyrenophora teres	36.14	1.00e-40	161.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	36.63	1.00e-40	161.00
IUUC-Rno-105125	Rattus norvegicus	87.70	0.00e+00	1127.00
IUUC-Sce-106192	Saccharomyces cerevisiae	28.25	3.00e-26	113.00
IUUC-Sha-107066	Sarcophilus harrisii	87.07	0.00e+00	1123.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	32.96	1.00e-40	161.00
IUUC-Spo-108220	Schizosaccharomyces pombe	36.89	9.00e-37	148.00
IUUC-Stu-112464	Solanum tuberosum	45.90	2.00e-13	71.60
IUUC-Sar-113393	Sorex araneus	92.63	2.00e-107	383.00
IUUC-Sre-114986	Sporisorium reilianum	38.97	2.00e-41	164.00
IUUC-Tgu-117505	Taeniopygia guttata	80.68	0.00e+00	1016.00
IUUC-Tru-118494	Takifugu rubripes	74.53	0.00e+00	962.00
IUUC-Tsy-119626	Tarsius syrichta	90.62	8.00e-47	181.00
IUUC-Tni-120174	Tetraodon nigroviridis	70.35	0.00e+00	946.00
IUUC-Tre-122191	Trichoderma reesei	33.70	1.00e-39	157.00
IUUC-Tvi-122318	Trichoderma virens	34.07	4.00e-41	162.00
IUUC-Tme-126914	Tuber melanosporum	36.16	5.00e-44	172.00
IUUC-Ttr-129095	Tursiops truncatus	89.29	0.00e+00	1186.00
IUUC-Uma-129475	Ustilago maydis	37.38	3.00e-38	154.00
IUUC-Vda-129908	Verticillium dahliae	33.09	3.00e-35	143.00
IUUC-Xtr-131900	Xenopus tropicalis	74.69	0.00e+00	996.00
IUUC-Xma-133124	Xiphophorus maculatus	74.86	0.00e+00	946.00
IUUC-Yli-134682	Yarrowia lipolytica	36.87	1.00e-32	134.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence