iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028153

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-conjugating enzyme E2R 2

Genbank Nucleotide ID

CU694487

Gene Name

ube2r2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000058740.4	ENSDART00000081666.4	ENSDARP00000076107.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.10e-49	166.1	13	153

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk... 87
           l+ elk+l+++p+eg+++++v+esdl++wev+i+Gp++t Yegg+Fk++i+fp dYP++PP+++fltk++hPn+yenG+vC+sil+   
   Q: 13   LMLELKSLQEEPVEGFRITLVEESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHppv 101
           678**********************************************************************************9999 PP
   S: 88   ........eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                   ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k+r 
   Q: 102  ddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRD 153
           99999*9*************************************99998875 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MAHQQMPSSQ KALMLELKSL QEEPVEGFRI TLVEESDLYN WEVAIFGPPN TLYEGGYFKA 60
HIKFPIDYPY SPPTFRFLTK MWHPNIYENG DVCISILHPP VDDPQSGELP SERWNPTQNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCATCAATA GAGGCGATTG AGAAACGGCG AGAGACATCA TCACCTGTCG ATTGCGTTCA 60
TGTATTTCTC CTGCGCTCCC ATTAATCTCC ATACACCACT TTCATAACAC TCATACCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

dre:436873

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003563	Anas platyrhynchos	92.52	4.00e-81	293.00
IUUC-Aca-004589	Anolis carolinensis	92.61	1.00e-112	399.00
IUUC-Ate-010563	Aspergillus terreus	47.19	5.00e-37	147.00
IUUC-Ame-011300	Astyanax mexicanus	96.00	5.00e-129	453.00
IUUC-Bta-012968	Bos taurus	94.74	2.00e-107	381.00
IUUC-Cja-018764	Callithrix jacchus	94.09	3.00e-114	404.00
IUUC-Cfa-020955	Canis familiaris	94.09	3.00e-114	404.00
IUUC-Cpo-021451	Cavia porcellus	94.09	3.00e-114	404.00
IUUC-Csa-024239	Chlorocebus sabaeus	94.09	3.00e-114	404.00
IUUC-Cho-024999	Choloepus hoffmanni	81.67	1.00e-25	110.00
IUUC-Cin-025344	Ciona intestinalis	71.72	5.00e-85	306.00
IUUC-Csv-025954	Ciona savignyi	69.90	1.00e-85	309.00
IUUC-Dno-029368	Dasypus novemcinctus	94.74	2.00e-107	381.00
IUUC-Dor-030686	Dipodomys ordii	94.09	3.00e-114	404.00
IUUC-Dme-032106	Drosophila melanogaster	73.96	2.00e-87	315.00
IUUC-Ete-033001	Echinops telfairi	92.17	3.00e-60	223.00
IUUC-Eca-034221	Equus caballus	93.15	2.00e-80	291.00
IUUC-Fca-036381	Felis catus	92.57	4.00e-81	293.00
IUUC-Fal-037135	Ficedula albicollis	94.09	4.00e-110	390.00
IUUC-Gmo-039565	Gadus morhua	94.97	6.00e-114	403.00
IUUC-Gga-040477	Gallus gallus	94.09	2.00e-110	391.00
IUUC-Gac-041909	Gasterosteus aculeatus	94.47	1.00e-113	402.00
IUUC-Ggo-045150	Gorilla gorilla	93.60	2.00e-113	401.00
IUUC-Hsa-046611	Homo sapiens	94.09	3.00e-114	404.00
IUUC-Itr-047984	Ictidomys tridecemlineatus	86.70	2.00e-100	358.00
IUUC-Lch-050173	Latimeria chalumnae	93.60	5.00e-114	403.00
IUUC-Loc-051916	Lepisosteus oculatus	96.52	1.00e-114	405.00
IUUC-Laf-053860	Loxodonta africana	94.09	3.00e-114	404.00
IUUC-Mcc-054820	Macaca mulatta	94.09	3.00e-114	404.00
IUUC-Meu-056681	Macropus eugenii	88.67	2.00e-107	381.00
IUUC-Mmr-060666	Microcebus murinus	94.09	3.00e-114	404.00
IUUC-Mdo-062804	Monodelphis domestica	94.09	1.00e-114	405.00
IUUC-Mmu-063472	Mus musculus	94.09	3.00e-114	404.00
IUUC-Mlu-067397	Myotis lucifugus	91.37	2.00e-106	377.00
IUUC-Nle-070152	Nomascus leucogenys	99.08	5.00e-63	231.00
IUUC-Ont-071627	Oreochromis niloticus	79.62	1.00e-115	409.00
IUUC-Ocu-074229	Oryctolagus cuniculus	94.76	5.00e-108	383.00
IUUC-Ola-086587	Oryzias latipes	78.46	2.00e-115	408.00
IUUC-Oga-089161	Otolemur garnettii	94.74	2.00e-107	381.00
IUUC-Oar-089383	Ovis aries	94.09	3.00e-114	404.00
IUUC-Ptr-091096	Pan troglodytes	94.09	3.00e-114	404.00
IUUC-Pan-092560	Papio anubis	94.74	2.00e-107	381.00
IUUC-Psi-093263	Pelodiscus sinensis	93.15	7.00e-81	292.00
IUUC-Pfo-096974	Poecilia formosa	78.24	3.00e-114	404.00
IUUC-Pab-098344	Pongo abelii	94.09	3.00e-114	404.00
IUUC-Rno-105821	Rattus norvegicus	94.09	3.00e-114	404.00
IUUC-Sha-107364	Sarcophilus harrisii	94.09	1.00e-114	405.00
IUUC-Sar-112992	Sorex araneus	90.55	2.00e-104	371.00
IUUC-Tgu-117074	Taeniopygia guttata	94.09	4.00e-110	390.00
IUUC-Tru-118641	Takifugu rubripes	78.08	1.00e-114	405.00
IUUC-Tsy-118797	Tarsius syrichta	93.48	2.00e-75	275.00
IUUC-Tni-119817	Tetraodon nigroviridis	80.00	4.00e-114	403.00
IUUC-Tbe-128014	Tupaia belangeri	94.09	3.00e-114	404.00
IUUC-Ttr-129037	Tursiops truncatus	94.05	9.00e-103	365.00
IUUC-Vpa-130680	Vicugna pacos	93.75	1.00e-79	288.00
IUUC-Xtr-131819	Xenopus tropicalis	96.76	1.00e-106	379.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence