iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020933

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03012573

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000019154.3	ENSCAFT00000030408.3	ENSCAFP00000028253.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	93.59	0.00e+00	900.00	IUUC-Hsa-045784
E3 activity/RING/RING	27.54	1.00e-28	122.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKS SEPVPQPHRP LDPLTMHSTY DRAGTVPRTP LSGPNIDYPV LYGKYLNGLG 120

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Nucleotide Sequence
(Fasta)

GCGCGCCGGG GGGGGCAGGA GGGCGCGCGG TGCTAATTGG CCGCCGCCGC GGCCCCGCCC 60
GCGAGTGGCG GGCGGTCACG TGACGCGACG GCTGGGGGCT CCCGGCGCGG GGGACGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	96.08	0.00e+00	891.00
IUUC-Apl-003765	Anas platyrhynchos	90.49	0.00e+00	808.00
IUUC-Ame-010763	Astyanax mexicanus	59.64	3.00e-147	515.00
IUUC-Bta-012369	Bos taurus	96.50	0.00e+00	916.00
IUUC-Cja-019450	Callithrix jacchus	93.01	0.00e+00	892.00
IUUC-Cpo-022112	Cavia porcellus	93.47	0.00e+00	862.00
IUUC-Csa-023913	Chlorocebus sabaeus	81.31	0.00e+00	730.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	27.72	4.00e-34	139.00
IUUC-Dre-027609	Danio rerio	59.59	2.00e-143	502.00
IUUC-Dno-029664	Dasypus novemcinctus	74.82	3.00e-150	525.00
IUUC-Ete-032988	Echinops telfairi	92.11	5.00e-171	593.00
IUUC-Eca-034430	Equus caballus	91.83	0.00e+00	885.00
IUUC-Fca-035968	Felis catus	99.32	6.00e-172	596.00
IUUC-Fal-037449	Ficedula albicollis	82.75	0.00e+00	799.00
IUUC-Fso-038103	Fusarium solani	35.19	1.00e-27	117.00
IUUC-Gmo-038925	Gadus morhua	61.52	1.00e-140	492.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.48	3.00e-30	126.00
IUUC-Gga-040362	Gallus gallus	85.08	0.00e+00	845.00
IUUC-Gac-042353	Gasterosteus aculeatus	59.59	6.00e-135	474.00
IUUC-Ggo-044810	Gorilla gorilla	91.65	0.00e+00	864.00
IUUC-Hsa-045784	Homo sapiens	93.59	0.00e+00	900.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	92.50	0.00e+00	873.00
IUUC-Lch-049727	Latimeria chalumnae	72.22	9.00e-153	532.00
IUUC-Loc-052354	Lepisosteus oculatus	53.99	2.00e-122	432.00
IUUC-Laf-054261	Loxodonta africana	94.95	0.00e+00	910.00
IUUC-Mcc-054931	Macaca mulatta	93.20	0.00e+00	897.00
IUUC-Meu-056468	Macropus eugenii	87.60	0.00e+00	866.00
IUUC-Mor-057185	Magnaporthe oryzae	31.00	5.00e-26	112.00
IUUC-Mpo-057405	Magnaporthe poae	33.19	1.00e-29	124.00
IUUC-Mtr-058267	Medicago truncatula	33.33	4.00e-18	87.00
IUUC-Mga-059981	Meleagris gallopavo	88.83	0.00e+00	707.00
IUUC-Mvi-060421	Microbotryum violaceum	28.75	9.00e-27	115.00
IUUC-Mmr-061181	Microcebus murinus	91.57	0.00e+00	852.00
IUUC-Mdo-062345	Monodelphis domestica	87.21	0.00e+00	865.00
IUUC-Mmu-063197	Mus musculus	87.57	0.00e+00	841.00
IUUC-Mpu-066275	Mustela putorius furo	95.53	0.00e+00	896.00
IUUC-Mlu-067194	Myotis lucifugus	95.16	0.00e+00	905.00
IUUC-Ncr-068929	Neurospora crassa	28.04	4.00e-28	119.00
IUUC-Ont-072227	Oreochromis niloticus	59.82	1.00e-140	493.00
IUUC-Oba-075731	Oryza barthii	42.86	1.00e-20	95.10
IUUC-Obr-076179	Oryza brachyantha	32.58	2.00e-20	94.70
IUUC-Ogl-077808	Oryza glaberrima	42.86	1.00e-20	95.10
IUUC-Ogu-078271	Oryza glumaepatula	42.86	1.00e-20	95.10
IUUC-Oin-079070	Oryza indica	42.86	1.00e-20	95.50
IUUC-Oru-084716	Oryza rufipogon	42.86	1.00e-20	95.50
IUUC-Ola-086865	Oryzias latipes	60.58	3.00e-138	485.00
IUUC-Oga-088945	Otolemur garnettii	94.17	0.00e+00	905.00
IUUC-Oar-089412	Ovis aries	91.41	0.00e+00	871.00
IUUC-Ptr-091550	Pan troglodytes	85.79	0.00e+00	644.00
IUUC-Pan-092183	Papio anubis	93.01	0.00e+00	897.00
IUUC-Psi-093003	Pelodiscus sinensis	83.14	0.00e+00	825.00
IUUC-Pfo-096704	Poecilia formosa	60.00	6.00e-143	500.00
IUUC-Pab-097923	Pongo abelii	97.90	0.00e+00	768.00
IUUC-Pca-100249	Procavia capensis	79.89	7.00e-145	506.00
IUUC-Pva-102562	Pteropus vampyrus	89.72	0.00e+00	847.00
IUUC-Rno-105762	Rattus norvegicus	88.35	0.00e+00	843.00
IUUC-Sce-106398	Saccharomyces cerevisiae	34.10	1.00e-28	121.00
IUUC-Sha-107253	Sarcophilus harrisii	86.43	0.00e+00	856.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	31.14	5.00e-30	126.00
IUUC-Sar-113149	Sorex araneus	86.57	2.00e-128	452.00
IUUC-Ssc-115241	Sus scrofa	97.09	0.00e+00	914.00
IUUC-Tgu-116884	Taeniopygia guttata	83.30	0.00e+00	796.00
IUUC-Tru-118031	Takifugu rubripes	60.27	8.00e-147	513.00
IUUC-Tni-119766	Tetraodon nigroviridis	60.27	7.00e-142	497.00
IUUC-Tre-122003	Trichoderma reesei	32.43	5.00e-28	119.00
IUUC-Ttr-128556	Tursiops truncatus	85.15	0.00e+00	749.00
IUUC-Vda-129985	Verticillium dahliae	34.26	4.00e-31	129.00
IUUC-Xtr-131866	Xenopus tropicalis	76.10	0.00e+00	754.00
IUUC-Xma-133963	Xiphophorus maculatus	60.05	8.00e-136	477.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence