iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054261

UUCD1 version

UUC-LoA-00312

Ensembl Protein ID

ENSLAFP00000007684.3

UniProt Accession

G3T387; G3T387_LOXAF

Protein Name

Uncharacterized protein

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009166.3	ENSLAFT00000009167.3	ENSLAFP00000007684.3
ENSLAFG00000009166.3	ENSLAFT00000037354.1	ENSLAFP00000029276.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.82	0.00e+00	906.00	IUUC-Hsa-045784
E3 activity/RING/RING	33.53	6.00e-28	120.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKH AEPVPQPHRP LDPLTMHSAY DRAGTLPRTP LSGPNIDYPV LYGKYLNGLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG AGCTGGTGGA GGCCAAAGTG AGTGAGCGGC GGCGGCGCCG GCCCGGGCGG 60
GCGGGCGAGG GGGCGGGGCG CGGCCGGGCG GCGAGCCGGG GCCTGCGCCT TCCGCCCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

KEGG

lav:100670291

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	91.96	0.00e+00	885.00
IUUC-Apl-003765	Anas platyrhynchos	80.78	0.00e+00	812.00
IUUC-Ame-010763	Astyanax mexicanus	59.51	4.00e-145	507.00
IUUC-Bta-012369	Bos taurus	93.59	0.00e+00	908.00
IUUC-Bci-013700	Botrytis cinerea	31.02	1.00e-27	117.00
IUUC-Bol-015380	Brassica oleracea	30.06	6.00e-18	85.90
IUUC-Cja-019450	Callithrix jacchus	92.23	0.00e+00	893.00
IUUC-Cfa-020933	Canis familiaris	94.95	0.00e+00	910.00
IUUC-Cpo-022112	Cavia porcellus	91.37	0.00e+00	865.00
IUUC-Csa-023913	Chlorocebus sabaeus	80.92	0.00e+00	722.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	34.42	4.00e-33	135.00
IUUC-Dre-027609	Danio rerio	58.90	5.00e-141	494.00
IUUC-Dno-029664	Dasypus novemcinctus	75.31	4.00e-156	545.00
IUUC-Ete-032988	Echinops telfairi	92.74	9.00e-173	599.00
IUUC-Eca-034430	Equus caballus	88.72	0.00e+00	867.00
IUUC-Fca-035968	Felis catus	96.23	3.00e-167	580.00
IUUC-Fal-037449	Ficedula albicollis	81.57	0.00e+00	799.00
IUUC-Fso-038103	Fusarium solani	34.72	5.00e-27	115.00
IUUC-Gmo-038925	Gadus morhua	60.29	7.00e-138	483.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.41	1.00e-29	124.00
IUUC-Gga-040362	Gallus gallus	83.91	0.00e+00	843.00
IUUC-Gac-042353	Gasterosteus aculeatus	58.45	5.00e-132	464.00
IUUC-Ggo-044810	Gorilla gorilla	90.49	0.00e+00	858.00
IUUC-Hsa-045784	Homo sapiens	92.82	0.00e+00	906.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	91.12	0.00e+00	877.00
IUUC-Lch-049727	Latimeria chalumnae	71.16	2.00e-151	528.00
IUUC-Loc-052354	Lepisosteus oculatus	53.76	2.00e-122	432.00
IUUC-Mcc-054931	Macaca mulatta	92.82	0.00e+00	890.00
IUUC-Meu-056468	Macropus eugenii	87.02	0.00e+00	875.00
IUUC-Mor-057185	Magnaporthe oryzae	29.82	3.00e-25	109.00
IUUC-Mpo-057405	Magnaporthe poae	32.77	9.00e-29	121.00
IUUC-Mtr-058267	Medicago truncatula	35.14	5.00e-19	89.70
IUUC-Mga-059981	Meleagris gallopavo	87.79	0.00e+00	700.00
IUUC-Mvi-060421	Microbotryum violaceum	28.57	3.00e-26	113.00
IUUC-Mmr-061181	Microcebus murinus	89.92	0.00e+00	852.00
IUUC-Mdo-062345	Monodelphis domestica	86.63	0.00e+00	873.00
IUUC-Mmu-063197	Mus musculus	87.38	0.00e+00	856.00
IUUC-Mpu-066275	Mustela putorius furo	93.20	0.00e+00	899.00
IUUC-Mlu-067194	Myotis lucifugus	93.04	0.00e+00	907.00
IUUC-Ncr-068929	Neurospora crassa	27.70	1.00e-27	117.00
IUUC-Ont-072227	Oreochromis niloticus	58.90	4.00e-138	484.00
IUUC-Oba-075731	Oryza barthii	43.81	4.00e-21	97.10
IUUC-Obr-076179	Oryza brachyantha	33.15	6.00e-21	96.30
IUUC-Ogl-077808	Oryza glaberrima	43.81	4.00e-21	97.10
IUUC-Ogu-078271	Oryza glumaepatula	43.81	4.00e-21	97.10
IUUC-Oin-079070	Oryza indica	43.81	3.00e-21	97.40
IUUC-Oru-084716	Oryza rufipogon	43.81	3.00e-21	97.40
IUUC-Osa-085685	Oryza sativa	42.86	9.00e-21	95.90
IUUC-Ola-086865	Oryzias latipes	59.62	4.00e-136	478.00
IUUC-Oga-088945	Otolemur garnettii	92.62	0.00e+00	911.00
IUUC-Oar-089412	Ovis aries	90.82	0.00e+00	867.00
IUUC-Ptr-091550	Pan troglodytes	84.47	0.00e+00	636.00
IUUC-Pan-092183	Papio anubis	92.62	0.00e+00	902.00
IUUC-Psi-093003	Pelodiscus sinensis	82.95	0.00e+00	831.00
IUUC-Pfo-096704	Poecilia formosa	59.77	1.00e-141	496.00
IUUC-Pab-097923	Pongo abelii	96.85	0.00e+00	764.00
IUUC-Pca-100249	Procavia capensis	81.54	1.00e-149	522.00
IUUC-Pva-102562	Pteropus vampyrus	87.75	0.00e+00	839.00
IUUC-Rno-105762	Rattus norvegicus	87.96	0.00e+00	859.00
IUUC-Sce-106398	Saccharomyces cerevisiae	33.53	3.00e-28	120.00
IUUC-Sha-107253	Sarcophilus harrisii	85.85	0.00e+00	864.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	34.98	1.00e-28	121.00
IUUC-Smo-109174	Selaginella moellendorffii	38.20	4.00e-14	73.60
IUUC-Sit-110527	Setaria italica	40.38	3.00e-19	90.90
IUUC-Sar-113149	Sorex araneus	86.94	2.00e-128	452.00
IUUC-Ssc-115241	Sus scrofa	93.98	0.00e+00	915.00
IUUC-Tgu-116884	Taeniopygia guttata	81.93	0.00e+00	795.00
IUUC-Tru-118031	Takifugu rubripes	59.13	8.00e-144	503.00
IUUC-Tni-119766	Tetraodon nigroviridis	59.13	6.00e-139	487.00
IUUC-Tre-122003	Trichoderma reesei	31.53	2.00e-27	117.00
IUUC-Ttr-128556	Tursiops truncatus	82.75	0.00e+00	735.00
IUUC-Vda-129985	Verticillium dahliae	33.80	2.00e-30	127.00
IUUC-Xtr-131866	Xenopus tropicalis	76.48	0.00e+00	765.00
IUUC-Xma-133963	Xiphophorus maculatus	59.59	1.00e-134	473.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence