iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000009693.10	ENSDART00000146121.2	ENSDARP00000114914.1
ENSDARG00000009693.10	ENSDART00000102540.3	ENSDARP00000093316.3
ENSDARG00000009693.10	ENSDART00000003511.9	ENSDARP00000024810.9

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-06	29.6	439	454

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 14   tllvsGsdDgtikvWD 29
            ll++G  Dgt++ WD
   Q: 439  ELLLTGHEDGTVRFWD 454
           579************* PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MMKFRFRRQG NDPHREKIKQ DLFAFNKTVE HGFPNQPSAL AYDPKLQLMA IGTKSGAIKI 60
YGAPGVEMTG LHKDTAAVTQ IHFLCGQGRI LSLLDDNTIH LWEIVQRENR SHLLEVHSFN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAAAACTTG CACGGCTTGA GGAGTGGATA CAAAAGAAAC GGGAGCTTGC ATGAAGGATC 60
ACATTGTTTC TCTGCACCGA CTGACGCCTA ACGGAATTCT TATCGATCTG AGACGTTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000664--Lethal2_giant
IPR013905--Lgl_C_dom
IPR013577--LLGL2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2

Pfam

PF08596--Lgl_C
PF08366--LLGL

PRINTS

PR00962--LETHAL2GIANT

SMART

SM00320--WD40

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0005737--C:cytoplasm
GO:0005096--F:GTPase activator activity
GO:0017137--F:Rab GTPase binding
GO:0003407--P:neural retina development
GO:0048919--P:posterior lateral line neuromast development
GO:0017157--P:regulation of exocytosis
GO:0008593--P:regulation of Notch signaling pathway
GO:0050708--P:regulation of protein secretion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001841	Ailuropoda melanoleuca	67.39	0.00e+00	1315.00
IUUC-Apl-003619	Anas platyrhynchos	61.55	0.00e+00	1115.00
IUUC-Aca-005314	Anolis carolinensis	74.15	0.00e+00	1505.00
IUUC-Ame-011869	Astyanax mexicanus	88.49	0.00e+00	1858.00
IUUC-Bta-013086	Bos taurus	65.93	0.00e+00	1416.00
IUUC-Cja-019964	Callithrix jacchus	66.85	0.00e+00	1360.00
IUUC-Cfa-021081	Canis familiaris	68.79	0.00e+00	1407.00
IUUC-Cpo-022226	Cavia porcellus	67.21	0.00e+00	1283.00
IUUC-Csa-023680	Chlorocebus sabaeus	67.79	0.00e+00	1378.00
IUUC-Cin-025693	Ciona intestinalis	48.34	0.00e+00	775.00
IUUC-Csv-025981	Ciona savignyi	49.52	0.00e+00	884.00
IUUC-Dno-028910	Dasypus novemcinctus	58.98	0.00e+00	1063.00
IUUC-Dor-030545	Dipodomys ordii	67.32	0.00e+00	1398.00
IUUC-Ete-033043	Echinops telfairi	64.51	2.00e-162	566.00
IUUC-Eca-034305	Equus caballus	67.34	0.00e+00	1342.00
IUUC-Eeu-035274	Erinaceus europaeus	57.14	0.00e+00	1022.00
IUUC-Fca-035636	Felis catus	67.64	0.00e+00	1346.00
IUUC-Fal-037109	Ficedula albicollis	73.88	0.00e+00	1529.00
IUUC-Gmo-039657	Gadus morhua	75.65	0.00e+00	1134.00
IUUC-Gga-040497	Gallus gallus	74.12	0.00e+00	1570.00
IUUC-Gac-041546	Gasterosteus aculeatus	74.03	0.00e+00	1534.00
IUUC-Ggo-045291	Gorilla gorilla	67.60	0.00e+00	1358.00
IUUC-Hsa-046004	Homo sapiens	68.08	0.00e+00	1359.00
IUUC-Itr-048031	Ictidomys tridecemlineatus	67.47	0.00e+00	1357.00
IUUC-Lch-049832	Latimeria chalumnae	73.17	0.00e+00	1426.00
IUUC-Loc-052641	Lepisosteus oculatus	80.43	0.00e+00	1702.00
IUUC-Laf-054218	Loxodonta africana	66.33	0.00e+00	1276.00
IUUC-Mcc-055013	Macaca mulatta	67.89	0.00e+00	1371.00
IUUC-Mga-060026	Meleagris gallopavo	69.82	0.00e+00	1405.00
IUUC-Mvi-060348	Microbotryum violaceum	22.74	6.00e-12	67.40
IUUC-Mmr-060930	Microcebus murinus	56.17	0.00e+00	1031.00
IUUC-Mdo-062135	Monodelphis domestica	75.33	0.00e+00	1566.00
IUUC-Mmu-063168	Mus musculus	67.82	0.00e+00	1381.00
IUUC-Mpu-066685	Mustela putorius furo	68.46	0.00e+00	1353.00
IUUC-Mlu-067389	Myotis lucifugus	67.35	0.00e+00	1419.00
IUUC-Nle-069136	Nomascus leucogenys	56.59	0.00e+00	1069.00
IUUC-Opr-070896	Ochotona princeps	66.79	0.00e+00	1356.00
IUUC-Ont-071498	Oreochromis niloticus	73.89	0.00e+00	1485.00
IUUC-Oan-073365	Ornithorhynchus anatinus	73.93	0.00e+00	1475.00
IUUC-Ocu-074863	Oryctolagus cuniculus	59.26	0.00e+00	1057.00
IUUC-Ola-086914	Oryzias latipes	71.75	0.00e+00	1497.00
IUUC-Oga-088401	Otolemur garnettii	68.37	0.00e+00	1370.00
IUUC-Oar-089232	Ovis aries	64.63	0.00e+00	1383.00
IUUC-Ptr-090647	Pan troglodytes	67.34	0.00e+00	1310.00
IUUC-Pan-092339	Papio anubis	67.60	0.00e+00	1373.00
IUUC-Psi-093016	Pelodiscus sinensis	65.80	0.00e+00	1206.00
IUUC-Pfo-096941	Poecilia formosa	75.33	0.00e+00	1558.00
IUUC-Pab-098102	Pongo abelii	67.49	0.00e+00	1345.00
IUUC-Pva-102768	Pteropus vampyrus	67.57	0.00e+00	1447.00
IUUC-Rno-105033	Rattus norvegicus	67.69	0.00e+00	1427.00
IUUC-Sha-106592	Sarcophilus harrisii	56.15	0.00e+00	1018.00
IUUC-Sar-113145	Sorex araneus	67.66	0.00e+00	874.00
IUUC-Tgu-117381	Taeniopygia guttata	59.05	0.00e+00	1107.00
IUUC-Tru-118539	Takifugu rubripes	75.46	0.00e+00	1454.00
IUUC-Tsy-119013	Tarsius syrichta	62.91	0.00e+00	675.00
IUUC-Tbe-127984	Tupaia belangeri	53.51	1.00e-155	543.00
IUUC-Ttr-128232	Tursiops truncatus	65.55	0.00e+00	1326.00
IUUC-Xtr-132060	Xenopus tropicalis	72.30	0.00e+00	1559.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence