iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042226

UUCD1 version

UUC-GaA-01206

Ensembl Protein ID

ENSGACP00000002041.1

UniProt Accession

G3N9Q0; G3N9Q0_GASAC

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000001560.1	ENSGACT00000002044.1	ENSGACP00000002041.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.10e-159	531.8	3	713

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 6    kewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqv 94
           k+wleLesdPglftllvedfg+k++ qvee+y+L++++    q pv+g+++lFk++e+r+s+rk++++ ++++v+de+i++ +ffa+q+
   Q: 3    KGWLELESDPGLFTLLVEDFGIKGV-QVEEIYDLQSKC----QSPVYGFIFLFKWIEERRSRRKVNTLMDETSVIDEEIVNDMFFAHQL 86
           89***********************.************....*********************************************** PP
   S: 95   igNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsy 183
           i+NsCat+Allsvllnc+ +  +lGttlsr+k +tk++spe+k++a+gn+++l+ +hns+ar+e+r++pe+q++ ++++t+eafhfvsy
   Q: 87   IPNSCATHALLSVLLNCSGV--ELGTTLSRMKAFTKGFSPESKGYAIGNAPELARAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSY 173
           ******************99..9****************************************************************** PP
   S: 184  vningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkid......... 259
           v+i++rl+eldglk++P+d+g+++e+ee++dk+++v+  +eri+l++++e    irfnl+a+v+drr++++ +l++lk +         
   Q: 174  VPIKDRLFELDGLKAYPIDHGPWGEEEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRMKYESKLEILKRNrqtvleglq 260
           *************************************..************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 261  kmirltqpelvqdkkqqessspddnspaikkeanaepvttqgadqvdesgdqsknaarpsgkvtgkppvppgggsqqisspnagvqrlp 349
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 350  afldnhnyakspmqeeedlaaavgrsraaglpkaqysddeddyedeeeevtgsastssrfrrkaslrsrpvravtgmesqialtvlaek 438
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 439  lkkeaqkkdalntplsvrtegrtggicitsasqpsptpsnestdtaseigsafnsplrsparsqaatrpsspvashlsrvlfgedemlr 527
           ***************************************************************************************** PP
   S: 260  ......................................................................................keL 262
                                                                                                 keL
   Q: 528  ldsrhnravrelgpsvsaallhlqedgiifalppsaaekegvnegdegpsverikeernegaevkpskekptatadskppgdkyspKEL 616
           ***************************************************************************************** PP
   S: 263  lkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveetisevrefgvnegrlakqrkqgrekki 351
           l+Llk++e+ ++++e  l++e+ekrkk+kidd+rRt+nydefic+fi++la+eg+l+ lve++is++r++gv++grl+kqrk++r+k++
   Q: 617  LALLKCVEADIANYEVYLKEEVEKRKKYKIDDQRRTHNYDEFICTFISMLAQEGMLASLVEQNISVRRRQGVSIGRLHKQRKPDRRKRS 705
           ***************************************************************************************** PP
   S: 352  rplkrkrk 359
           rp+k+kr+
   Q: 706  RPYKAKRQ 713
           ******97 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MNKGWLELES DPGLFTLLVE DFGIKGVQVE EIYDLQSKCQ SPVYGFIFLF KWIEERRSRR 60
KVNTLMDETS VIDEEIVNDM FFAHQLIPNS CATHALLSVL LNCSGVELGT TLSRMKAFTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCCAAT TCTCTCTATT GTGTTTATCT TGAGCTCTCT TCAGTTATTT CGCGAATGGA 60
TACAGCTTTA TCGTTTGAGA TTATTAGACC TCTTCCGAAC ATGGACTGGA ACACAACTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001263	Ailuropoda melanoleuca	67.61	0.00e+00	896.00
IUUC-Apl-003405	Anas platyrhynchos	56.05	8.00e-130	457.00
IUUC-Aca-004836	Anolis carolinensis	68.81	0.00e+00	926.00
IUUC-Ame-011946	Astyanax mexicanus	71.08	0.00e+00	1000.00
IUUC-Bta-013131	Bos taurus	64.60	0.00e+00	753.00
IUUC-Cja-019599	Callithrix jacchus	69.14	0.00e+00	929.00
IUUC-Cfa-021003	Canis familiaris	68.02	0.00e+00	897.00
IUUC-Cpo-022143	Cavia porcellus	68.29	0.00e+00	911.00
IUUC-Csa-023477	Chlorocebus sabaeus	69.00	0.00e+00	920.00
IUUC-Cho-024734	Choloepus hoffmanni	52.00	5.00e-125	441.00
IUUC-Csv-025842	Ciona savignyi	57.04	6.00e-94	337.00
IUUC-Dre-027793	Danio rerio	74.67	0.00e+00	1071.00
IUUC-Dno-029253	Dasypus novemcinctus	68.71	0.00e+00	905.00
IUUC-Dor-030891	Dipodomys ordii	63.04	0.00e+00	834.00
IUUC-Dme-031796	Drosophila melanogaster	62.64	1.00e-93	337.00
IUUC-Ete-032646	Echinops telfairi	85.54	2.00e-121	429.00
IUUC-Eca-033805	Equus caballus	68.19	0.00e+00	914.00
IUUC-Eeu-035216	Erinaceus europaeus	67.12	1.00e-95	343.00
IUUC-Fca-035611	Felis catus	67.68	0.00e+00	864.00
IUUC-Fal-037186	Ficedula albicollis	68.68	0.00e+00	815.00
IUUC-Gmo-038824	Gadus morhua	83.91	0.00e+00	762.00
IUUC-Gga-040875	Gallus gallus	69.34	0.00e+00	924.00
IUUC-Ggo-045122	Gorilla gorilla	68.78	0.00e+00	926.00
IUUC-Hsa-045882	Homo sapiens	68.87	0.00e+00	926.00
IUUC-Itr-048185	Ictidomys tridecemlineatus	68.27	0.00e+00	917.00
IUUC-Lch-049960	Latimeria chalumnae	64.48	0.00e+00	848.00
IUUC-Loc-052408	Lepisosteus oculatus	74.95	0.00e+00	647.00
IUUC-Laf-054187	Loxodonta africana	68.84	0.00e+00	927.00
IUUC-Mcc-055273	Macaca mulatta	67.92	0.00e+00	897.00
IUUC-Meu-056267	Macropus eugenii	86.97	6.00e-141	494.00
IUUC-Mga-059958	Meleagris gallopavo	82.03	9.00e-146	509.00
IUUC-Mmr-061280	Microcebus murinus	68.24	0.00e+00	905.00
IUUC-Mdo-062625	Monodelphis domestica	69.05	0.00e+00	959.00
IUUC-Mmu-063853	Mus musculus	68.89	0.00e+00	913.00
IUUC-Mlu-067771	Myotis lucifugus	68.99	0.00e+00	904.00
IUUC-Opr-070741	Ochotona princeps	68.07	0.00e+00	911.00
IUUC-Ont-072172	Oreochromis niloticus	86.52	0.00e+00	1231.00
IUUC-Oan-073167	Ornithorhynchus anatinus	67.53	0.00e+00	911.00
IUUC-Ocu-074176	Oryctolagus cuniculus	68.54	0.00e+00	892.00
IUUC-Ola-087203	Oryzias latipes	91.29	9.00e-146	509.00
IUUC-Oga-089153	Otolemur garnettii	67.30	0.00e+00	898.00
IUUC-Oar-090008	Ovis aries	67.57	0.00e+00	910.00
IUUC-Ptr-091234	Pan troglodytes	68.87	0.00e+00	926.00
IUUC-Pan-092005	Papio anubis	69.00	0.00e+00	927.00
IUUC-Psi-093995	Pelodiscus sinensis	75.66	1.00e-167	583.00
IUUC-Pma-094110	Petromyzon marinus	47.72	6.00e-112	397.00
IUUC-Pfo-097418	Poecilia formosa	85.09	0.00e+00	1182.00
IUUC-Pab-098267	Pongo abelii	68.87	0.00e+00	902.00
IUUC-Pca-101084	Procavia capensis	67.63	0.00e+00	868.00
IUUC-Pva-102292	Pteropus vampyrus	68.67	0.00e+00	641.00
IUUC-Rno-105251	Rattus norvegicus	67.51	0.00e+00	893.00
IUUC-Sha-107100	Sarcophilus harrisii	68.36	0.00e+00	942.00
IUUC-Sar-113559	Sorex araneus	62.95	4.00e-117	415.00
IUUC-Ssc-115688	Sus scrofa	67.88	0.00e+00	911.00
IUUC-Tgu-117424	Taeniopygia guttata	69.93	0.00e+00	942.00
IUUC-Tru-118585	Takifugu rubripes	84.01	0.00e+00	1192.00
IUUC-Tsy-119299	Tarsius syrichta	57.33	0.00e+00	627.00
IUUC-Tni-120808	Tetraodon nigroviridis	86.85	0.00e+00	1201.00
IUUC-Tbe-127705	Tupaia belangeri	73.99	3.00e-147	514.00
IUUC-Ttr-128225	Tursiops truncatus	67.76	0.00e+00	897.00
IUUC-Vpa-130193	Vicugna pacos	69.55	4.00e-92	332.00
IUUC-Xtr-132449	Xenopus tropicalis	66.10	0.00e+00	855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence