iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-042307

Ensembl Protein ID

ENSGACP00000023510.2

UniProt Accession

G3Q0W5; G3Q0W5_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000017787.2	ENSGACT00000023556.2	ENSGACP00000023510.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-39	132.4	1810	1843
UBD/Beta-Prp	5.20e-71	239.7	1418	1680

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           gH++ vtclaf +d + l+sG+ D+ + vWD+++
   Q: 1810 GHSGAVTCLAFsPDgGQLLSGGKDKALLVWDVSS 1843
           8***********999****************976 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           +sv tc+  s d++l+++g  +g++ + +++tg  ++sl +  ++++++ + +dg  l+t+s D+ i +wd+ +g+ +  ++gh + 
   Q: 1418 SSVPTCLVGSSDGELMVVGTGRGMLHLISTRTGHEVKSLVSSCDGISSCVLLKDG-RLATTSFDGRIEIWDIANGCRTALIQGHANV 1503
           789999999******************************8888899999999998.9****************************** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           ++  ++ +++++lv+ s d +++vw   +g ++     + ++  ncv+++p+g ll++G+ ++ v +W+  +++ l  ltg h +sv
   Q: 1504 ITGSDLTADRKHLVTVSLDFMLKVWSSAKGHEVA--ALPSSSPLNCVTFDPEGHLLAAGCWNGNVIVWNWLQNRTLASLTG-HRRSV 1587
           *********************************8..5667778*************************************9.***** PP
   S: 184  yslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW..dlrsgdllktlqlhn..ss 266
           +s+sf++++  l sgs  g v+lw++ +++cv  +++h+     ++f++ +  l++++sD  +++W   l  + +l++l+       
   Q: 1588 RSVSFSPSSSMLCSGSISGEVRLWSVPSSTCVGCFQAHRGAAEALAFLDGGSTLLTAGSDHLLQLWsgGLGRSPPLQKLKSATsePA 1674
           ******************************************************************887777778887777653322 PP
   S: 267  visvav 272
             +vav
   Q: 1675 ALCVAV 1680
           333333 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

VIRLSRDISV RDPQFLLKVA VYTRQELNIR ITANFLLALA ANLPSTKPHV RRYFCAAVQL 60
PSDWLEVVRI YSAVSLGGRS LPSCLKKAMA DKFKQFNEYQ LAKYNTRKHR CKHSRNRPKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCATCCGCC TGTCCAGGGA CATCTCTGTC CGCGACCCGC AGTTTCTCCT CAAGGTGAGT 60
TTGCAGGTCT GTGTGTGAAT CTGGAGACGT TTCTGTTTGT ACGTCAAACT CGCTCTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0003723--F:RNA binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	36.17	0.00e+00	1006.00
IUUC-Aca-005102	Anolis carolinensis	37.95	0.00e+00	1101.00
IUUC-Ame-011822	Astyanax mexicanus	48.80	0.00e+00	1457.00
IUUC-Bta-012323	Bos taurus	35.70	0.00e+00	1006.00
IUUC-Cja-019005	Callithrix jacchus	35.87	0.00e+00	1083.00
IUUC-Cfa-020803	Canis familiaris	36.56	0.00e+00	962.00
IUUC-Cpo-022312	Cavia porcellus	35.90	0.00e+00	1005.00
IUUC-Csa-023287	Chlorocebus sabaeus	35.75	0.00e+00	1050.00
IUUC-Dre-028825	Danio rerio	52.63	0.00e+00	1884.00
IUUC-Dno-029455	Dasypus novemcinctus	34.79	0.00e+00	925.00
IUUC-Dor-030328	Dipodomys ordii	32.84	7.00e-180	625.00
IUUC-Ete-032385	Echinops telfairi	38.49	0.00e+00	701.00
IUUC-Eca-033726	Equus caballus	36.03	0.00e+00	1027.00
IUUC-Eeu-034665	Erinaceus europaeus	39.57	5.00e-98	353.00
IUUC-Fca-035365	Felis catus	36.97	0.00e+00	742.00
IUUC-Gmo-039584	Gadus morhua	57.13	0.00e+00	1079.00
IUUC-Ggo-045432	Gorilla gorilla	34.56	0.00e+00	985.00
IUUC-Hsa-046182	Homo sapiens	35.88	0.00e+00	1071.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	36.23	0.00e+00	1035.00
IUUC-Lch-050186	Latimeria chalumnae	36.22	1.00e-68	254.00
IUUC-Laf-054524	Loxodonta africana	36.14	0.00e+00	1076.00
IUUC-Mcc-055628	Macaca mulatta	35.89	0.00e+00	1050.00
IUUC-Meu-056338	Macropus eugenii	36.69	2.00e-176	614.00
IUUC-Mmr-060854	Microcebus murinus	36.43	0.00e+00	1050.00
IUUC-Mdo-062247	Monodelphis domestica	35.71	0.00e+00	1021.00
IUUC-Mmu-064406	Mus musculus	35.92	0.00e+00	987.00
IUUC-Mpu-065806	Mustela putorius furo	36.65	0.00e+00	1053.00
IUUC-Mlu-068116	Myotis lucifugus	36.90	0.00e+00	710.00
IUUC-Nle-069628	Nomascus leucogenys	35.78	0.00e+00	1043.00
IUUC-Opr-070242	Ochotona princeps	32.86	0.00e+00	661.00
IUUC-Oan-073598	Ornithorhynchus anatinus	34.93	2.00e-153	538.00
IUUC-Ocu-073933	Oryctolagus cuniculus	36.26	0.00e+00	1030.00
IUUC-Ola-086886	Oryzias latipes	62.76	0.00e+00	2256.00
IUUC-Oga-088609	Otolemur garnettii	35.55	0.00e+00	993.00
IUUC-Oar-089957	Ovis aries	36.44	0.00e+00	988.00
IUUC-Ptr-090577	Pan troglodytes	35.78	0.00e+00	1058.00
IUUC-Pan-092397	Papio anubis	35.95	0.00e+00	1048.00
IUUC-Pma-094373	Petromyzon marinus	33.45	1.00e-26	114.00
IUUC-Pfo-096497	Poecilia formosa	61.52	0.00e+00	2157.00
IUUC-Pab-098028	Pongo abelii	35.76	0.00e+00	1052.00
IUUC-Pca-101002	Procavia capensis	35.65	3.00e-166	580.00
IUUC-Pva-102144	Pteropus vampyrus	38.91	1.00e-160	561.00
IUUC-Rno-105828	Rattus norvegicus	36.39	0.00e+00	980.00
IUUC-Sha-106469	Sarcophilus harrisii	35.87	0.00e+00	1023.00
IUUC-Sar-113035	Sorex araneus	31.39	8.00e-119	422.00
IUUC-Ssc-116122	Sus scrofa	34.87	0.00e+00	676.00
IUUC-Tru-118412	Takifugu rubripes	62.67	0.00e+00	2387.00
IUUC-Tsy-119257	Tarsius syrichta	35.09	8.00e-101	363.00
IUUC-Tni-120032	Tetraodon nigroviridis	67.00	8.00e-108	383.00
IUUC-Tbe-127312	Tupaia belangeri	44.18	2.00e-81	298.00
IUUC-Ttr-128335	Tursiops truncatus	35.53	0.00e+00	880.00
IUUC-Xtr-132524	Xenopus tropicalis	35.24	0.00e+00	1037.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence