iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117617

UUCD1 version

UUC-TaR-01044

Ensembl Protein ID

ENSTRUP00000013895.1

UniProt Accession

H2SNA9; H2SNA9_TAKRU

Protein Name

Uncharacterized protein

Gene Name

cdc34a; cdc34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000005720.1	ENSTRUT00000013957.1	ENSTRUP00000013894.1
ENSTRUG00000005720.1	ENSTRUT00000013958.1	ENSTRUP00000013895.1
ENSTRUG00000005720.1	ENSTRUT00000013959.1	ENSTRUP00000013896.1
ENSTRUG00000005720.1	ENSTRUT00000013960.1	ENSTRUP00000013897.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	8.50e-45	153.2	15	165

Active Site

Position(s)	Description	Evidence
105	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFk..........leiefpedYPfkPPkvkfltkifhPnvyenGk 80
           l+ e+k+l+++p+eg+++++vdesd+++wev+i+Gp++t Yegg+Fk          ++i+fp dYP++PP ++fltk++hPn+yenG+
   Q: 15   LMLEMKSLQDEPVEGFKITLVDESDMYNWEVAIFGPPNTHYEGGYFKxkxksnthlqARIKFPVDYPYSPPAFRFLTKMWHPNIYENGD 103
           688*******************************************73333333333579***************************** PP
   S: 81   vClsilk...........eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
           vC+sil+           ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k+re
   Q: 104  VCISILHppvddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWRE 165
           ******999999999*9******************************************998 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MAQHGHHVAS SQKALMLEMK SLQDEPVEGF KITLVDESDM YNWEVAIFGP PNTHYEGGYF 60
KXKXKSNTHL QARIKFPVDY PYSPPAFRFL TKMWHPNIYE NGDVCISILH PPVDDPQSGE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACTCGAGAC CTCTAGTGCC TGGATAGTTG AGTAAAGTTA AAATGAACAG ATGGGCTATT 60
TACGCGTTAC TGTCCCGTGT TAAGACATAT TTATTGACAT TTCGATGCTA CTCAGCCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011425	Astyanax mexicanus	86.57	3.00e-110	390.00
IUUC-Dre-028367	Danio rerio	89.35	5.00e-113	399.00
IUUC-Gmo-039011	Gadus morhua	89.77	1.00e-114	405.00
IUUC-Gac-042276	Gasterosteus aculeatus	93.49	2.00e-118	417.00
IUUC-Ont-071924	Oreochromis niloticus	91.63	1.00e-116	411.00
IUUC-Pfo-097436	Poecilia formosa	93.49	3.00e-118	417.00
IUUC-Tni-120864	Tetraodon nigroviridis	93.49	2.00e-118	417.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence