iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066473

Ensembl Protein ID

ENSMPUP00000015278.1

UniProt Accession

M3YVB8; M3YVB8_MUSPF

Genbank Protein ID

ENSMPUP00000015278

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01021880

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000015388.1	ENSMPUT00000015517.1	ENSMPUP00000015278.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.10e-08	34.0	13	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle+fk+ p+++pCgH f+  Cl + w     ++    +CP Cr
   Q: 13   CSICLEPFKE-PVTTPCGHNFCGLCLdETW----AVQGSPYLCPQCR 54
           ********99.*******************....8899999*****8 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAELVPLAEE LSCSICLEPF KEPVTTPCGH NFCGLCLDET WAVQGSPYLC PQCRASYHAR 60
PQLRKNTVLC AVVEQFLQAE EARATPPPPD DWKLPTRAAT PSPAGPVACD HCLKEAAVKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNCTCCC GCCGCTCAGT TTCGTTTCCT CGCGGGCCTC 60
AGGCGGTCGA GTCTGGCAGT CGCGGCCACA GTTCCAGCGC GTCCCGTCCA GTCCCCAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	85.13	0.00e+00	1072.00
IUUC-Apl-004101	Anas platyrhynchos	49.14	2.00e-171	595.00
IUUC-Aca-005025	Anolis carolinensis	48.69	9.00e-179	620.00
IUUC-Bta-012735	Bos taurus	74.69	0.00e+00	958.00
IUUC-Cja-019996	Callithrix jacchus	69.40	5.00e-180	623.00
IUUC-Cfa-020466	Canis familiaris	77.95	0.00e+00	1027.00
IUUC-Cpo-021737	Cavia porcellus	69.67	0.00e+00	887.00
IUUC-Csa-023217	Chlorocebus sabaeus	76.86	0.00e+00	972.00
IUUC-Cho-024346	Choloepus hoffmanni	49.50	2.00e-69	255.00
IUUC-Dno-030082	Dasypus novemcinctus	72.48	0.00e+00	943.00
IUUC-Dor-030335	Dipodomys ordii	51.45	4.00e-124	438.00
IUUC-Ete-032923	Echinops telfairi	67.68	0.00e+00	792.00
IUUC-Eca-033411	Equus caballus	74.24	0.00e+00	955.00
IUUC-Eeu-034656	Erinaceus europaeus	74.20	7.00e-167	580.00
IUUC-Fca-035371	Felis catus	80.28	0.00e+00	1037.00
IUUC-Fal-037008	Ficedula albicollis	47.44	1.00e-90	327.00
IUUC-Gmo-038668	Gadus morhua	35.43	4.00e-107	382.00
IUUC-Gga-040608	Gallus gallus	47.99	2.00e-166	579.00
IUUC-Gac-041409	Gasterosteus aculeatus	33.61	2.00e-59	223.00
IUUC-Ggo-044518	Gorilla gorilla	76.36	0.00e+00	950.00
IUUC-Hsa-045828	Homo sapiens	76.86	0.00e+00	967.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	70.69	5.00e-135	474.00
IUUC-Lch-050478	Latimeria chalumnae	39.30	6.00e-71	261.00
IUUC-Loc-052864	Lepisosteus oculatus	36.35	4.00e-111	395.00
IUUC-Laf-054325	Loxodonta africana	76.76	3.00e-171	594.00
IUUC-Mcc-054920	Macaca mulatta	77.17	0.00e+00	975.00
IUUC-Meu-056367	Macropus eugenii	71.43	1.00e-73	270.00
IUUC-Mga-059975	Meleagris gallopavo	49.69	3.00e-168	585.00
IUUC-Mmr-060748	Microcebus murinus	74.41	0.00e+00	938.00
IUUC-Mdo-062904	Monodelphis domestica	56.60	0.00e+00	681.00
IUUC-Mmu-063891	Mus musculus	69.47	0.00e+00	901.00
IUUC-Mlu-068185	Myotis lucifugus	74.88	0.00e+00	932.00
IUUC-Nle-070177	Nomascus leucogenys	76.40	0.00e+00	967.00
IUUC-Opr-070558	Ochotona princeps	58.66	3.00e-143	501.00
IUUC-Ont-071368	Oreochromis niloticus	35.15	3.00e-108	385.00
IUUC-Ocu-074461	Oryctolagus cuniculus	67.62	1.00e-152	533.00
IUUC-Ola-086503	Oryzias latipes	27.25	2.00e-53	203.00
IUUC-Oga-088937	Otolemur garnettii	69.15	0.00e+00	875.00
IUUC-Oar-089781	Ovis aries	70.77	0.00e+00	643.00
IUUC-Ptr-090771	Pan troglodytes	76.71	0.00e+00	957.00
IUUC-Pan-092830	Papio anubis	77.33	0.00e+00	976.00
IUUC-Psi-093664	Pelodiscus sinensis	50.94	1.00e-177	616.00
IUUC-Pma-094147	Petromyzon marinus	27.41	6.00e-60	225.00
IUUC-Pfo-096528	Poecilia formosa	35.72	3.00e-114	405.00
IUUC-Pab-097588	Pongo abelii	76.55	0.00e+00	962.00
IUUC-Pca-100890	Procavia capensis	71.13	1.00e-158	553.00
IUUC-Pva-102314	Pteropus vampyrus	78.45	0.00e+00	967.00
IUUC-Rno-105234	Rattus norvegicus	70.54	0.00e+00	899.00
IUUC-Sce-106362	Saccharomyces cerevisiae	43.48	2.00e-08	53.10
IUUC-Sha-106807	Sarcophilus harrisii	55.00	0.00e+00	667.00
IUUC-Sar-113283	Sorex araneus	56.17	3.00e-130	458.00
IUUC-Ssc-115878	Sus scrofa	81.55	2.00e-109	388.00
IUUC-Tgu-117026	Taeniopygia guttata	45.94	6.00e-131	460.00
IUUC-Tru-118624	Takifugu rubripes	27.18	1.00e-54	207.00
IUUC-Tbe-127580	Tupaia belangeri	73.63	7.00e-158	550.00
IUUC-Ttr-128648	Tursiops truncatus	69.34	0.00e+00	642.00
IUUC-Vpa-130254	Vicugna pacos	85.80	3.00e-93	335.00
IUUC-Xtr-132892	Xenopus tropicalis	41.55	1.00e-72	266.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence