iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028008

Ensembl Protein ID

ENSDARP00000121892.1

UniProt Accession

E9QEH6; E9QEH6_DANRE

Genbank Protein ID

ENSDARP00000121892

Protein Name

SREBF chaperone

Genbank Nucleotide ID

BX511123

Gene Name

scap

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000018096.9	ENSDART00000141130.1	ENSDARP00000121892.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.70e-17	61.3	1083	1116

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++++t++   d t+ l+sG+ Dg i vWD+ tg
   Q: 1083 GHSGGITAIYI-DqTMvLASGGQDGAICVWDVLTG 1116
           8********88.446648*************9887 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MTVRERLRQN ISAAFYRHGL LCASYPVPII LFTSASILTC CYPLLKLPLP GTGPVEFTTG 60
VRDYSIPSHE SQGDLSERPD WYRGPPVAYI QQVLVKAAVS PWGNSLVPVD VFRSPLGRVF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAACACTA GAGACTCACA GCCACCTGCC TGCTGCAGCT CAACGAGAGC TATTCACTGT 60
TAATAAAAGC CCTCGAAGAG GAAGAGAAGC ACCCGCCATT AGGGTAAGCG ATCATTTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0006629--P:lipid metabolic process
GO:0019915--P:lipid storage
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	73.38	0.00e+00	829.00
IUUC-Apl-003294	Anas platyrhynchos	69.57	0.00e+00	1580.00
IUUC-Aca-004424	Anolis carolinensis	64.03	0.00e+00	1394.00
IUUC-Bta-013478	Bos taurus	68.47	0.00e+00	1525.00
IUUC-Cel-018160	Caenorhabditis elegans	26.08	2.00e-73	271.00
IUUC-Cja-019123	Callithrix jacchus	66.56	0.00e+00	1447.00
IUUC-Cfa-021082	Canis familiaris	67.93	0.00e+00	1470.00
IUUC-Cpo-022477	Cavia porcellus	66.49	0.00e+00	1428.00
IUUC-Csa-023176	Chlorocebus sabaeus	67.11	0.00e+00	1477.00
IUUC-Cin-025490	Ciona intestinalis	39.96	4.00e-93	336.00
IUUC-Csv-026115	Ciona savignyi	39.03	3.00e-135	476.00
IUUC-Dno-028887	Dasypus novemcinctus	70.77	0.00e+00	905.00
IUUC-Dor-030467	Dipodomys ordii	74.66	0.00e+00	678.00
IUUC-Dme-032087	Drosophila melanogaster	32.54	3.00e-111	397.00
IUUC-Ete-032372	Echinops telfairi	57.70	0.00e+00	1222.00
IUUC-Eca-033896	Equus caballus	67.87	0.00e+00	1554.00
IUUC-Eeu-035099	Erinaceus europaeus	65.20	0.00e+00	867.00
IUUC-Fca-035616	Felis catus	71.70	0.00e+00	839.00
IUUC-Fal-037231	Ficedula albicollis	67.87	0.00e+00	1514.00
IUUC-Gmo-039439	Gadus morhua	83.72	0.00e+00	774.00
IUUC-Gac-041516	Gasterosteus aculeatus	82.28	0.00e+00	1899.00
IUUC-Hsa-046674	Homo sapiens	68.68	0.00e+00	1532.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	67.67	0.00e+00	1538.00
IUUC-Lch-049689	Latimeria chalumnae	66.41	0.00e+00	1541.00
IUUC-Loc-052417	Lepisosteus oculatus	77.02	0.00e+00	713.00
IUUC-Laf-053795	Loxodonta africana	67.82	0.00e+00	1531.00
IUUC-Mcc-055502	Macaca mulatta	68.16	0.00e+00	1535.00
IUUC-Mga-059805	Meleagris gallopavo	69.80	0.00e+00	1569.00
IUUC-Mmr-060997	Microcebus murinus	67.62	0.00e+00	1552.00
IUUC-Mdo-062940	Monodelphis domestica	67.60	0.00e+00	1505.00
IUUC-Mmu-063255	Mus musculus	67.23	0.00e+00	1506.00
IUUC-Mpu-066158	Mustela putorius furo	68.19	0.00e+00	1528.00
IUUC-Mlu-067201	Myotis lucifugus	66.49	0.00e+00	1477.00
IUUC-Nle-069145	Nomascus leucogenys	71.57	0.00e+00	974.00
IUUC-Opr-070797	Ochotona princeps	64.11	0.00e+00	1399.00
IUUC-Ont-071553	Oreochromis niloticus	82.60	0.00e+00	1924.00
IUUC-Ocu-074598	Oryctolagus cuniculus	68.14	0.00e+00	1524.00
IUUC-Ola-086650	Oryzias latipes	93.69	1.00e-122	432.00
IUUC-Oar-089287	Ovis aries	65.65	0.00e+00	817.00
IUUC-Pan-092004	Papio anubis	68.33	0.00e+00	1504.00
IUUC-Psi-093028	Pelodiscus sinensis	64.49	0.00e+00	1359.00
IUUC-Pma-094145	Petromyzon marinus	50.11	0.00e+00	1100.00
IUUC-Pfo-096320	Poecilia formosa	83.83	0.00e+00	1935.00
IUUC-Pab-097862	Pongo abelii	68.65	0.00e+00	1535.00
IUUC-Pca-100862	Procavia capensis	58.14	0.00e+00	1158.00
IUUC-Pva-103050	Pteropus vampyrus	70.80	0.00e+00	953.00
IUUC-Rno-105852	Rattus norvegicus	67.93	0.00e+00	1518.00
IUUC-Sha-107312	Sarcophilus harrisii	68.05	0.00e+00	1530.00
IUUC-Sar-113311	Sorex araneus	63.11	6.00e-176	612.00
IUUC-Ssc-116356	Sus scrofa	68.75	0.00e+00	1563.00
IUUC-Tgu-116896	Taeniopygia guttata	55.91	5.00e-144	505.00
IUUC-Tru-118197	Takifugu rubripes	81.98	0.00e+00	1910.00
IUUC-Tni-119823	Tetraodon nigroviridis	78.82	0.00e+00	1811.00
IUUC-Ttr-129164	Tursiops truncatus	68.21	0.00e+00	1534.00
IUUC-Xtr-132819	Xenopus tropicalis	65.20	0.00e+00	1562.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence