iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045261

UUCD1 version

UUC-GoG-00270

Ensembl Protein ID

ENSGGOP00000006668.2

UniProt Accession

G3QVA4; G3QVA4_GORGO

Protein Name

Uncharacterized protein

Gene Name

GNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000006810.2	ENSGGOT00000006841.2	ENSGGOP00000006668.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.20e-43	142.8	206	242
UBD/Beta-Prp	4.60e-55	187.3	118	322

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH++++++++f ++ + +++GsdD t++++Dlr +  
   Q: 206  GHESDINAICFfPNgNAFATGSDDATCRLFDLRADQE 242
           8*********99777*****************98865 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetl 133
            r+l gh++  ++++f +d   +vt+s D t  +wd++tg+++ t++gh+ +v+sls+ p++  +vsG  d  +++wd+++g c + t+
   Q: 118  SRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQ-TF 204
           6899***************7.7****************************************************************.** PP
   S: 134  sghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlngh 221
           +gh++ +n +++ p+gn +++Gs+D t+rl+dl+ ++ l t    +    ++s+sf+++g+ l++g +d   ++wd  + +    l gh
   Q: 205  TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYsHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGH 293
           ************************************999999434455789************************************** PP
   S: 222  tdnvksvrfspnderlvsgssDgsiriWd 250
           ++ v+++ +++++  +++gs D  ++iW+
   Q: 294  DNRVSCLGVTDDGMAVATGSWDSFLKIWN 322
           ****************************8 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

QDARKACADA TLSQITNNID PVGRIQMRTR RTLRGHLAKI YAMHWGTDSR LLVSASQDGK 60
LIIWDSYTTN KVHAIPLRSS WVMTCAYAPS GNYVACGGLD NICSIYNLKT REGNVRVSRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGACGCCA GGAAAGCATG TGCAGATGCA ACTCTCTCTC AGGTAAGAGC CCACTGAGTC 60
ACGCAGAGCC ATCTGCCTGT GAGGAGGCTA GCACGGCACC CACACCTGGA GCCTCGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005834--C:heterotrimeric G-protein complex
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0001750--C:photoreceptor outer segment
GO:0003924--F:GTPase activity
GO:0008283--P:cell proliferation
GO:0007200--P:phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0060041--P:retina development in camera-type eye
GO:0050909--P:sensory perception of taste

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001337	Ailuropoda melanoleuca	99.69	0.00e+00	630.00
IUUC-Bta-012709	Bos taurus	99.69	0.00e+00	630.00
IUUC-Cja-019782	Callithrix jacchus	99.69	0.00e+00	630.00
IUUC-Cfa-020111	Canis familiaris	99.69	0.00e+00	630.00
IUUC-Cpo-022494	Cavia porcellus	99.69	0.00e+00	630.00
IUUC-Csa-023672	Chlorocebus sabaeus	99.69	0.00e+00	630.00
IUUC-Dre-028478	Danio rerio	98.45	0.00e+00	657.00
IUUC-Dor-030964	Dipodomys ordii	92.86	2.00e-158	551.00
IUUC-Eca-033359	Equus caballus	99.38	0.00e+00	629.00
IUUC-Gmo-039709	Gadus morhua	98.14	0.00e+00	655.00
IUUC-Hsa-046450	Homo sapiens	99.69	0.00e+00	630.00
IUUC-Itr-049064	Ictidomys tridecemlineatus	99.69	0.00e+00	630.00
IUUC-Laf-054222	Loxodonta africana	99.69	0.00e+00	630.00
IUUC-Mcc-054970	Macaca mulatta	99.69	0.00e+00	630.00
IUUC-Meu-056109	Macropus eugenii	99.35	1.00e-172	598.00
IUUC-Mmr-061302	Microcebus murinus	99.38	0.00e+00	629.00
IUUC-Mdo-062044	Monodelphis domestica	99.07	0.00e+00	626.00
IUUC-Mmu-063323	Mus musculus	99.69	0.00e+00	630.00
IUUC-Mlu-067309	Myotis lucifugus	99.69	0.00e+00	630.00
IUUC-Nle-069791	Nomascus leucogenys	99.69	0.00e+00	630.00
IUUC-Ocu-073769	Oryctolagus cuniculus	99.69	0.00e+00	630.00
IUUC-Ola-087490	Oryzias latipes	96.89	0.00e+00	627.00
IUUC-Oga-087961	Otolemur garnettii	99.69	0.00e+00	630.00
IUUC-Pan-092079	Papio anubis	99.69	0.00e+00	630.00
IUUC-Pab-098658	Pongo abelii	99.69	0.00e+00	630.00
IUUC-Pca-100313	Procavia capensis	99.07	4.00e-179	620.00
IUUC-Pva-102636	Pteropus vampyrus	99.38	0.00e+00	629.00
IUUC-Rno-105112	Rattus norvegicus	99.69	0.00e+00	630.00
IUUC-Sha-106856	Sarcophilus harrisii	99.07	0.00e+00	626.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence