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Tag Content
iUUCD ID IUUC-Aml-001362
Ensembl Protein ID ENSAMEP00000001105.1
UniProt Accession G1L2J5; G1L2J5_AILME
Genbank Protein ID ENSAMEP00000001105
Protein Name Uncharacterized protein
Genbank Nucleotide ID ACTA01156426
Gene Name VAV3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000001012.1 ENSAMET00000001149.1 ENSAMEP00000001105.1
ENSAMEG00000001012.1 ENSAMET00000001155.1 ENSAMEP00000001111.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.00e-14 54.3 794 845
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ yd+ a +  eL+l kGdvv++   +   +gW++g  e +g+ G fP+ +ve+
   Q: 794  IARYDFCARDMRELSLLKGDVVKIY-TKMSANGWWRG--EVNGRVGWFPSTYVEE 845
           688*********************9.999999*****..9*************86 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
MEPWKQCAQW LIHCKVLPAN HRVTWDSAQV FDLAQTLRDG VLLCQLLNNL RAHSINLKEI 60
NLRPQMSQFL CLKNIRTFLT ACCETFGMRK SELFEAFDLF DVRDFGKVIE TLSRLSRTPI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001362|UBD,SH3|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGAGCCGT GGAAGCAGTG CGCGCAGTGG CTCATCCACT GCAAGGTGCT GCCCGCCAAC 60
CACCGGGTGA CCTGGGACTC GGCGCAGGTG TTCGACCTGG CGCAGACCCT CCGCGATGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001362|UBD,SH3|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc
Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain
IPR003096--SM22_calponin
PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2
Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2
PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00888--SM22CALPONIN
SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3
Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0046872--F:metal ion binding
GO:0030676--F:Rac guanyl-nucleotide exchange factor activity
GO:0050853--P:B cell receptor signaling pathway
GO:0006974--P:cellular response to DNA damage stimulus
GO:0007229--P:integrin-mediated signaling pathway
GO:0030032--P:lamellipodium assembly
GO:0030593--P:neutrophil chemotaxis
GO:0030890--P:positive regulation of B cell proliferation
GO:0045785--P:positive regulation of cell adhesion
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0008361--P:regulation of cell size
GO:0035023--P:regulation of Rho protein signal transduction
GO:0042493--P:response to drug
GO:0007264--P:small GTPase mediated signal transduction
GO:0006906--P:vesicle fusion
KEGG aml:100480126
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003734 Anas platyrhynchos 87.03 0.00e+00 1358.00
IUUC-Aca-004477 Anolis carolinensis 82.40 0.00e+00 1397.00
IUUC-Ame-011279 Astyanax mexicanus 66.31 0.00e+00 1116.00
IUUC-Bta-012722 Bos taurus 95.75 0.00e+00 1601.00
IUUC-Cja-018941 Callithrix jacchus 96.90 0.00e+00 1596.00
IUUC-Cfa-020266 Canis familiaris 98.42 0.00e+00 1456.00
IUUC-Cpo-021966 Cavia porcellus 94.93 0.00e+00 1378.00
IUUC-Csa-023892 Chlorocebus sabaeus 96.16 0.00e+00 1470.00
IUUC-Cin-025115 Ciona intestinalis 36.80 2.00e-135 476.00
IUUC-Csv-025995 Ciona savignyi 35.03 8.00e-145 507.00
IUUC-Dre-028199 Danio rerio 66.44 0.00e+00 1117.00
IUUC-Dno-029474 Dasypus novemcinctus 96.69 0.00e+00 1617.00
IUUC-Eca-033961 Equus caballus 97.89 0.00e+00 1476.00
IUUC-Eeu-034719 Erinaceus europaeus 69.78 0.00e+00 1085.00
IUUC-Fca-036572 Felis catus 97.37 0.00e+00 1588.00
IUUC-Fal-036802 Ficedula albicollis 85.49 0.00e+00 1491.00
IUUC-Gmo-039409 Gadus morhua 69.80 0.00e+00 1165.00
IUUC-Gga-040884 Gallus gallus 86.30 0.00e+00 1477.00
IUUC-Gac-041395 Gasterosteus aculeatus 71.68 0.00e+00 1244.00
IUUC-Ggo-044460 Gorilla gorilla 94.23 0.00e+00 1392.00
IUUC-Hsa-046099 Homo sapiens 93.71 0.00e+00 1597.00
IUUC-Itr-048144 Ictidomys tridecemlineatus 92.35 0.00e+00 1393.00
IUUC-Lch-049650 Latimeria chalumnae 82.16 4.00e-110 389.00
IUUC-Loc-052487 Lepisosteus oculatus 73.62 0.00e+00 1243.00
IUUC-Laf-054564 Loxodonta africana 95.28 0.00e+00 1596.00
IUUC-Mcc-054622 Macaca mulatta 93.26 0.00e+00 1590.00
IUUC-Meu-056680 Macropus eugenii 85.95 0.00e+00 1424.00
IUUC-Mga-060013 Meleagris gallopavo 82.62 0.00e+00 1396.00
IUUC-Mmr-061251 Microcebus murinus 91.61 0.00e+00 1610.00
IUUC-Mdo-061875 Monodelphis domestica 93.51 0.00e+00 1571.00
IUUC-Mmu-063735 Mus musculus 95.04 0.00e+00 1612.00
IUUC-Mpu-065856 Mustela putorius furo 98.11 0.00e+00 1632.00
IUUC-Mlu-068108 Myotis lucifugus 91.31 0.00e+00 1523.00
IUUC-Nle-069863 Nomascus leucogenys 92.41 0.00e+00 1561.00
IUUC-Opr-070372 Ochotona princeps 84.17 0.00e+00 1047.00
IUUC-Ont-072286 Oreochromis niloticus 72.46 0.00e+00 1238.00
IUUC-Ocu-074194 Oryctolagus cuniculus 96.69 0.00e+00 1612.00
IUUC-Ola-086336 Oryzias latipes 70.94 0.00e+00 1226.00
IUUC-Oga-089104 Otolemur garnettii 58.89 0.00e+00 968.00
IUUC-Oar-089272 Ovis aries 95.99 0.00e+00 1646.00
IUUC-Ptr-090652 Pan troglodytes 94.58 0.00e+00 1596.00
IUUC-Pan-092550 Papio anubis 92.51 0.00e+00 1402.00
IUUC-Psi-093784 Pelodiscus sinensis 81.44 0.00e+00 1273.00
IUUC-Ppa-095161 Physcomitrella patens 43.64 3.00e-09 56.20
IUUC-Pfo-097308 Poecilia formosa 69.67 0.00e+00 1225.00
IUUC-Pab-098698 Pongo abelii 94.57 0.00e+00 1598.00
IUUC-Pva-102262 Pteropus vampyrus 96.52 0.00e+00 1547.00
IUUC-Rno-105421 Rattus norvegicus 94.81 0.00e+00 1621.00
IUUC-Sha-107325 Sarcophilus harrisii 93.51 0.00e+00 1589.00
IUUC-Sar-113456 Sorex araneus 90.67 0.00e+00 1531.00
IUUC-Ssc-115338 Sus scrofa 57.42 0.00e+00 883.00
IUUC-Tgu-116595 Taeniopygia guttata 83.89 0.00e+00 1399.00
IUUC-Tru-117884 Takifugu rubripes 66.59 0.00e+00 1197.00
IUUC-Tsy-119429 Tarsius syrichta 87.55 0.00e+00 1319.00
IUUC-Tni-119951 Tetraodon nigroviridis 69.24 0.00e+00 1146.00
IUUC-Tbe-127995 Tupaia belangeri 85.25 2.00e-179 622.00
IUUC-Ttr-128281 Tursiops truncatus 96.93 0.00e+00 1614.00
IUUC-Xtr-132427 Xenopus tropicalis 72.62 0.00e+00 1288.00
Created Date 25-Jun-2017

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