iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cin-025115

Ensembl Protein ID

ENSCINP00000017775.3

UniProt Accession

F6WCA3; F6WCA3_CIOIN

Genbank Protein ID

ENSCINP00000017775

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01002834

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000008711.3	ENSCINT00000017775.3	ENSCINP00000017775.3
ENSCING00000008711.3	ENSCINT00000026172.2	ENSCINP00000025926.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.60e-16	59.2	799	854

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
             vl+++++ +  eL l++G  v vi+ +    gW+kg  e eg+ G fP+ Fve+++
   Q: 799  AVVLFNFSPRSPQELGLREGQPVNVISTAGDAHGWWKG--ESEGQVGYFPATFVEEIR 854
           579***********************999*********..9**************996 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

KELWRQCVRW LTDTGVLPRD HKTCQPHAVV FDLAQTLRDG VILCNLLNVI QPGSVDFTQI 60
NLRPQMLQFS CLQNIRTTLH ALNNVFRLQE TFLPSDLYDM TNIPLVLQVL SLLSQTPASQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGGAATTGT GGCGTCAGTG TGTACGCTGG CTGACGGACA CTGGTGTACT GCCCAGAGAC 60
CATAAAACCT GCCAACCTCA TGCTGTTGTG TTTGACCTGG CACAAACATT AAGAGATGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00307--CH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001362	Ailuropoda melanoleuca	36.16	5.00e-128	450.00
IUUC-Apl-003262	Anas platyrhynchos	35.33	7.00e-133	466.00
IUUC-Aca-004477	Anolis carolinensis	35.90	3.00e-128	451.00
IUUC-Ame-011608	Astyanax mexicanus	37.11	6.00e-154	536.00
IUUC-Bta-012722	Bos taurus	35.59	1.00e-127	449.00
IUUC-Cel-018578	Caenorhabditis elegans	29.91	1.00e-62	233.00
IUUC-Cja-020009	Callithrix jacchus	37.86	2.00e-137	481.00
IUUC-Cfa-020768	Canis familiaris	38.13	1.00e-136	478.00
IUUC-Cpo-021543	Cavia porcellus	33.03	4.00e-102	364.00
IUUC-Csa-024204	Chlorocebus sabaeus	34.98	1.00e-135	475.00
IUUC-Csv-025995	Ciona savignyi	67.82	0.00e+00	1139.00
IUUC-Cne-027023	Cryptococcus neoformans	23.32	2.00e-11	63.90
IUUC-Cme-027247	Cyanidioschyzon merolae	21.65	2.00e-11	62.80
IUUC-Dre-028308	Danio rerio	35.67	1.00e-150	525.00
IUUC-Dno-029602	Dasypus novemcinctus	37.53	2.00e-135	475.00
IUUC-Dor-031014	Dipodomys ordii	30.96	1.00e-82	299.00
IUUC-Eca-033448	Equus caballus	35.11	1.00e-130	459.00
IUUC-Eeu-034719	Erinaceus europaeus	28.26	7.00e-52	197.00
IUUC-Fca-035629	Felis catus	37.90	5.00e-142	496.00
IUUC-Fal-036684	Ficedula albicollis	35.71	1.00e-137	482.00
IUUC-Gmo-039409	Gadus morhua	35.82	3.00e-131	461.00
IUUC-Gga-040999	Gallus gallus	36.76	9.00e-141	493.00
IUUC-Gac-041395	Gasterosteus aculeatus	37.41	1.00e-139	489.00
IUUC-Ggo-044558	Gorilla gorilla	35.52	8.00e-138	483.00
IUUC-Hsa-046208	Homo sapiens	35.63	7.00e-139	486.00
IUUC-Itr-048730	Ictidomys tridecemlineatus	36.72	4.00e-130	457.00
IUUC-Lch-049650	Latimeria chalumnae	38.86	2.00e-32	130.00
IUUC-Loc-052827	Lepisosteus oculatus	35.02	2.00e-143	501.00
IUUC-Laf-054537	Loxodonta africana	38.06	3.00e-143	501.00
IUUC-Mcc-055054	Macaca mulatta	35.67	5.00e-139	487.00
IUUC-Meu-056680	Macropus eugenii	38.34	1.00e-88	320.00
IUUC-Mga-060106	Meleagris gallopavo	35.69	5.00e-136	477.00
IUUC-Mmr-061118	Microcebus murinus	35.22	2.00e-134	472.00
IUUC-Mdo-061875	Monodelphis domestica	36.63	9.00e-134	469.00
IUUC-Mmu-063135	Mus musculus	36.11	1.00e-138	486.00
IUUC-Mpu-066000	Mustela putorius furo	38.25	5.00e-137	480.00
IUUC-Mlu-067818	Myotis lucifugus	38.09	6.00e-134	470.00
IUUC-Ncr-068849	Neurospora crassa	38.30	6.00e-06	44.70
IUUC-Nle-069863	Nomascus leucogenys	34.85	8.00e-121	426.00
IUUC-Opr-070372	Ochotona princeps	32.17	1.00e-73	270.00
IUUC-Ont-071945	Oreochromis niloticus	35.65	9.00e-143	499.00
IUUC-Oan-073384	Ornithorhynchus anatinus	33.02	4.00e-99	354.00
IUUC-Ocu-074194	Oryctolagus cuniculus	36.46	4.00e-128	451.00
IUUC-Ola-086336	Oryzias latipes	36.84	3.00e-139	488.00
IUUC-Oga-089104	Otolemur garnettii	38.20	2.00e-136	478.00
IUUC-Oar-089272	Ovis aries	36.24	5.00e-132	463.00
IUUC-Ptr-090507	Pan troglodytes	35.76	1.00e-136	479.00
IUUC-Pan-092325	Papio anubis	36.65	3.00e-140	491.00
IUUC-Psi-094021	Pelodiscus sinensis	36.29	7.00e-136	476.00
IUUC-Pma-094372	Petromyzon marinus	32.77	7.00e-89	320.00
IUUC-Pfo-096732	Poecilia formosa	35.24	5.00e-142	497.00
IUUC-Pab-098630	Pongo abelii	37.49	8.00e-134	469.00
IUUC-Pca-100295	Procavia capensis	34.75	5.00e-117	414.00
IUUC-Pva-102406	Pteropus vampyrus	37.99	1.00e-127	449.00
IUUC-Rno-105332	Rattus norvegicus	35.55	2.00e-134	471.00
IUUC-Sha-107325	Sarcophilus harrisii	36.37	1.00e-135	475.00
IUUC-Sar-113456	Sorex araneus	34.09	7.00e-121	426.00
IUUC-Ssc-115338	Sus scrofa	37.28	2.00e-121	428.00
IUUC-Tgu-116595	Taeniopygia guttata	35.99	9.00e-127	446.00
IUUC-Tru-117884	Takifugu rubripes	36.43	3.00e-141	494.00
IUUC-Tsy-119429	Tarsius syrichta	34.51	5.00e-62	231.00
IUUC-Tni-120835	Tetraodon nigroviridis	35.69	2.00e-132	465.00
IUUC-Tbe-127995	Tupaia belangeri	34.62	1.00e-47	183.00
IUUC-Ttr-128281	Tursiops truncatus	35.86	3.00e-125	441.00
IUUC-Xtr-132747	Xenopus tropicalis	36.19	2.00e-135	474.00
IUUC-Xma-133428	Xiphophorus maculatus	37.70	4.00e-141	494.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence