iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118335

UUCD1 version

UUC-TaR-00563

Ensembl Protein ID

ENSTRUP00000027007.1

UniProt Accession

H2TQQ0; H2TQQ0_TAKRU

Protein Name

Uncharacterized protein

Gene Name

wdr37 (1 of many); LOC101078020

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000010707.1	ENSTRUT00000027116.1	ENSTRUP00000027007.1
ENSTRUG00000010707.1	ENSTRUT00000027117.1	ENSTRUP00000027008.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.60e-24	84.4	375	406
UBD/Beta-Prp	6.60e-46	158.1	286	496

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 375  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 406
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtl 90
           tlk+ h++v+ + ++  ++++++t+s+d+   +++v+t  l+++l gh++e t ++ +p++ + vt+s+D t ++wd++++++  v ++
   Q: 286  TLKS-HQGVVIAADWLVGGRQVVTASWDRAANLYEVETSELVHTLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVF 373
           4444.555666699999**************************************************************665422889* PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtlt 176
           +gh+d+v+s  f   gd +vsGs+drt++vwdl++          +d++vn ++v+ ++++++  +++r+vrl+d+   + ++l r  +
   Q: 374  QGHTDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPI-ATIRTDSAVNRISVSANQRIIALPHDNRQVRLFDMsgvRLARLPRSNR 460
           *********99999.********************99987.7788899****************************7878888888889 PP
   S: 177  gghtdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            gh ++v +++++++     l +++ d++ + w++ 
   Q: 461  MGHRRMVCCTAWNEENqsCNLFTCGFDRQAIGWNIN 496
           99*********999984456799*********9986 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MPGEGGSTSG SALAGRHPKQ KRKAHSLSIR RTNSTEERPL GILRGDMLEG QDSKLPLSLR 60
NNLLDLFSQI EREFENLYIE NIELRREIDS LNERLTGDGQ TVEGGDPSKG VLKTKETASH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCATGTGAT ACGGAAGTAA GTGCAGCAAC AAAATAAGTG ATGTGTCAAA TTTTACATTA 60
TTCGGGATCT TTCTTGGTTA CTGCTGTAGA TTTTTAAGGA CACACGCGGA CATTTCCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018499	Caenorhabditis elegans	40.43	1.00e-88	320.00
IUUC-Cin-025460	Ciona intestinalis	45.40	6.00e-104	370.00
IUUC-Dme-031936	Drosophila melanogaster	48.94	7.00e-116	410.00
IUUC-Gmo-038476	Gadus morhua	91.63	0.00e+00	858.00
IUUC-Gac-042110	Gasterosteus aculeatus	92.48	0.00e+00	887.00
IUUC-Ont-071816	Oreochromis niloticus	94.05	0.00e+00	930.00
IUUC-Ola-087068	Oryzias latipes	93.45	0.00e+00	959.00
IUUC-Pfo-097088	Poecilia formosa	93.75	0.00e+00	812.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence