iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Opu-083370

Ensembl Protein ID

OPUNC03G28830.1

UniProt Accession

A0A0E0KI52; A0A0E0KI52_ORYPU

Protein Name

Coatomer subunit alpha

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OPUNC03G28830	OPUNC03G28830.1	OPUNC03G28830.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-39	131.6	50	86
UBD/Beta-Prp	3.40e-77	260.4	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++t+++l
   Q: 50   HDGPVRGVHFhaTQPLFVSGGDDYKIKVWNYKTHRCL 86
           99*********6449********************98 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           t +++++++++ + f+p +++++++  +g i+ wd+++g+ll ++ +h+++v+ v f+ +++++v+g++D+ ikvw+++t  c+ tl+gh d++
   Q: 3    TKFETKSNRVKGLSFHPRRPWILASLHSGVIQMWDYRMGTLLDRFDEHDGPVRGVHFHATQPLFVSGGDDYKIKVWNYKTHRCLFTLHGHLDYI 96
           67889999************************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl......................... 166
           ++++f+ +  ++vs+s+d+tir+w++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                         
   Q: 97   RTVQFHHEYPWIVSASDDQTIRIWNWQSRTCVA-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgalrkktvspaddilrltqmntdlf 189
           *********************************.*************************************************97777777777 PP
   S: 167  ..ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
               + + + l+g h++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+siriWd ++++ 
   Q: 190  ggVDAVVKYVLEG-HDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRIWDATKRTG 282
           6444444444466.********************************777668****************************************** PP
   S: 257  lktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           ++t+ +++++++  ++ +++ n l++g  ds   ++kl++++p
   Q: 283  IQTFRREHDRFWILSA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           ****************.6666655555.689999999988765 PP

Organism

Oryza punctata

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPR RPWILASLHS GVIQMWDYRM GTLLDRFDEH DGPVRGVHFH 60
ATQPLFVSGG DDYKIKVWNY KTHRCLFTLH GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGACCA AGTTCGAGAC GAAGAGCAAC CGGGTGAAGG GTCTGAGCTT CCACCCGCGG 60
CGGCCATGGA TCCTTGCCAG CCTCCACAGC GGGGTGATCC AGATGTGGGA CTACCGCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005154	Anolis carolinensis	77.03	3.00e-95	340.00
IUUC-Acl-008027	Aspergillus clavatus	47.03	0.00e+00	1105.00
IUUC-Ame-011229	Astyanax mexicanus	52.92	0.00e+00	1297.00
IUUC-Bgr-012300	Blumeria graminis	46.82	0.00e+00	1077.00
IUUC-Bta-012524	Bos taurus	54.85	0.00e+00	1340.00
IUUC-Cpo-021813	Cavia porcellus	55.12	0.00e+00	1361.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	69.59	0.00e+00	1239.00
IUUC-Dor-030290	Dipodomys ordii	53.17	1.00e-166	580.00
IUUC-Dse-031543	Dothistroma septosporum	45.97	0.00e+00	1056.00
IUUC-Dme-031945	Drosophila melanogaster	60.58	0.00e+00	1023.00
IUUC-Ete-032873	Echinops telfairi	52.57	0.00e+00	1197.00
IUUC-Fal-037263	Ficedula albicollis	50.81	0.00e+00	1192.00
IUUC-Gmo-039602	Gadus morhua	50.44	0.00e+00	1216.00
IUUC-Gga-040590	Gallus gallus	54.57	0.00e+00	1346.00
IUUC-Lch-049706	Latimeria chalumnae	54.52	0.00e+00	1338.00
IUUC-Loc-051867	Lepisosteus oculatus	49.88	0.00e+00	818.00
IUUC-Mmr-061102	Microcebus murinus	54.30	0.00e+00	1335.00
IUUC-Mmu-063736	Mus musculus	54.56	0.00e+00	1348.00
IUUC-Nle-069634	Nomascus leucogenys	65.87	0.00e+00	950.00
IUUC-Ont-072488	Oreochromis niloticus	53.46	0.00e+00	1314.00
IUUC-Olo-080466	Oryza longistaminata	98.90	0.00e+00	1696.00
IUUC-Oni-082608	Oryza nivara	98.19	0.00e+00	2340.00
IUUC-Osa-085841	Oryza sativa	98.03	0.00e+00	2343.00
IUUC-Ola-086921	Oryzias latipes	52.84	0.00e+00	1306.00
IUUC-Pan-092475	Papio anubis	54.73	0.00e+00	1352.00
IUUC-Pab-098497	Pongo abelii	54.93	0.00e+00	1360.00
IUUC-Rno-105428	Rattus norvegicus	54.97	0.00e+00	1355.00
IUUC-Sce-106464	Saccharomyces cerevisiae	42.14	0.00e+00	939.00
IUUC-Spo-108217	Schizosaccharomyces pombe	44.41	0.00e+00	1056.00
IUUC-Smo-109582	Selaginella moellendorffii	74.56	0.00e+00	1364.00
IUUC-Tsy-119105	Tarsius syrichta	51.88	0.00e+00	1025.00
IUUC-Tae-125527	Triticum aestivum	93.51	0.00e+00	2290.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence