iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003927

Ensembl Protein ID

ENSAPLP00000010806.1

UniProt Accession

U3IU83; U3IU83_ANAPL

Genbank Protein ID

ENSAPLP00000010806

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01089269

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000011021.1	ENSAPLT00000011524.1	ENSAPLP00000010806.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-29	100.3	629	666
UBD/Beta-Prp	3.20e-45	154.3	544	703

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H d vt+la  ++  +l sGs+D++i++W+l + ++++
   Q: 629  HLDAVTSLAVdPNgLYLMSGSHDCSIRLWNLESKTCIQ 666
           99*********77799***************9999987 PP

UBD/Beta-Prp

   S: 16   vkf.spdksllatgsrdgtikvwdvttgkllrslsgheae.......vtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           v+  s d sl+++++ +g + +++++t + + +l++  ++       ++ v  +p+ +i +t++eDr+ik +d +tgk +h++ +h d 
   Q: 544  VDLvSSDPSLMVASFNTGHTSIFNMETRQRILTLESGVDTtvssscqINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLDA 632
           555578999*********************9999555555466666666666677777******************************* PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlW 164
           v+sl+++p+g +l sGshd  ir+w+le+++c++e     ++ d+++  v++hp++++++s+++D   +++
   Q: 633  VTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEftaHRKKFDESIHDVAFHPSKCYIASAGADALAKVF 703
           **********************************877666777889999****************988887 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

LQAQIAFLQG ERKGQENLKK DLVRRIKMLE YALKQESRAK YHKLKYGTEL NQGDMKPPNY 60
DSDEGNETEI QPQQNSQLIW KQGRQLLRQY LQEVGYTDTI LDVKSKQVRA LLGLSSDASE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCAGGCCC AGATCGCTTT CCTTCAAGGT GAAAGGAAGG GACAAGAAAA TCTGAAGAAG 60
GATCTAGTGC GGAGAATCAA AATGCTGGAA TATGCACTTA AACAGGAAAG GTACATTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	87.66	0.00e+00	1182.00
IUUC-Aca-004933	Anolis carolinensis	84.88	0.00e+00	1176.00
IUUC-Ame-010997	Astyanax mexicanus	75.63	0.00e+00	982.00
IUUC-Bta-013077	Bos taurus	87.80	0.00e+00	1182.00
IUUC-Cja-018973	Callithrix jacchus	88.65	0.00e+00	1191.00
IUUC-Cfa-020988	Canis familiaris	84.38	0.00e+00	1125.00
IUUC-Cpo-022496	Cavia porcellus	87.80	0.00e+00	1194.00
IUUC-Csa-023829	Chlorocebus sabaeus	88.37	0.00e+00	1189.00
IUUC-Dre-028560	Danio rerio	70.47	0.00e+00	896.00
IUUC-Dno-029742	Dasypus novemcinctus	82.84	0.00e+00	1129.00
IUUC-Dor-030721	Dipodomys ordii	79.43	0.00e+00	1056.00
IUUC-Eca-033760	Equus caballus	87.93	0.00e+00	1179.00
IUUC-Eeu-034953	Erinaceus europaeus	90.36	0.00e+00	714.00
IUUC-Fca-036530	Felis catus	87.64	0.00e+00	1182.00
IUUC-Fal-037353	Ficedula albicollis	91.40	0.00e+00	969.00
IUUC-Gmo-039094	Gadus morhua	72.84	7.00e-178	617.00
IUUC-Gga-040132	Gallus gallus	97.87	0.00e+00	1213.00
IUUC-Gac-041713	Gasterosteus aculeatus	74.03	0.00e+00	967.00
IUUC-Ggo-045455	Gorilla gorilla	78.42	0.00e+00	998.00
IUUC-Hsa-046415	Homo sapiens	88.09	0.00e+00	1186.00
IUUC-Lch-050475	Latimeria chalumnae	84.44	0.00e+00	1117.00
IUUC-Loc-051859	Lepisosteus oculatus	79.16	0.00e+00	1060.00
IUUC-Laf-053537	Loxodonta africana	88.23	0.00e+00	1205.00
IUUC-Mcc-055817	Macaca mulatta	88.37	0.00e+00	1189.00
IUUC-Meu-055946	Macropus eugenii	65.48	0.00e+00	765.00
IUUC-Mga-059694	Meleagris gallopavo	97.44	0.00e+00	1209.00
IUUC-Mmr-060768	Microcebus murinus	88.37	0.00e+00	1189.00
IUUC-Mdo-061901	Monodelphis domestica	84.33	0.00e+00	1164.00
IUUC-Mmu-064154	Mus musculus	86.38	0.00e+00	1169.00
IUUC-Mpu-065827	Mustela putorius furo	82.43	0.00e+00	1169.00
IUUC-Mlu-067102	Myotis lucifugus	88.23	0.00e+00	1188.00
IUUC-Ncr-068831	Neurospora crassa	39.60	3.00e-22	100.00
IUUC-Nle-070008	Nomascus leucogenys	88.35	0.00e+00	1187.00
IUUC-Opr-071067	Ochotona princeps	56.01	6.00e-150	524.00
IUUC-Ont-072025	Oreochromis niloticus	74.83	0.00e+00	964.00
IUUC-Oan-072950	Ornithorhynchus anatinus	88.77	0.00e+00	1139.00
IUUC-Ocu-074316	Oryctolagus cuniculus	87.64	0.00e+00	1172.00
IUUC-Ola-087279	Oryzias latipes	72.14	0.00e+00	929.00
IUUC-Oga-088284	Otolemur garnettii	87.80	0.00e+00	1188.00
IUUC-Oar-090304	Ovis aries	87.94	0.00e+00	1185.00
IUUC-Ptr-091052	Pan troglodytes	88.23	0.00e+00	1187.00
IUUC-Pan-092270	Papio anubis	85.15	0.00e+00	1154.00
IUUC-Psi-093907	Pelodiscus sinensis	91.59	0.00e+00	1070.00
IUUC-Pfo-097042	Poecilia formosa	73.46	0.00e+00	1035.00
IUUC-Pab-098110	Pongo abelii	88.23	0.00e+00	1187.00
IUUC-Pca-100266	Procavia capensis	75.21	0.00e+00	818.00
IUUC-Pva-102824	Pteropus vampyrus	86.38	0.00e+00	1144.00
IUUC-Pgr-103483	Puccinia graminis	37.28	8.00e-57	215.00
IUUC-Rno-105638	Rattus norvegicus	87.09	0.00e+00	1180.00
IUUC-Sha-107004	Sarcophilus harrisii	84.32	0.00e+00	1080.00
IUUC-Ssc-115280	Sus scrofa	88.09	0.00e+00	1189.00
IUUC-Tgu-116759	Taeniopygia guttata	97.44	0.00e+00	1229.00
IUUC-Tru-117944	Takifugu rubripes	74.83	0.00e+00	968.00
IUUC-Tsy-119405	Tarsius syrichta	78.09	0.00e+00	989.00
IUUC-Tni-120571	Tetraodon nigroviridis	74.16	0.00e+00	979.00
IUUC-Vpa-130294	Vicugna pacos	87.48	0.00e+00	1167.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence