iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106686

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01119454

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000018397.1	ENSSHAT00000021900.1	ENSSHAP00000021726.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.40e-86	288.5	446	949

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCYmNSv+Q+L++ +++r+++l+     l+e    +++++l+++lq lf+ l +s++ avsp+++l+a +   + fs  +qq
   Q: 446  GLINLGNTCYMNSVIQALFMASDFRHCVLH-----LPE----DNSQPLMTKLQWLFAFLEHSQRPAVSPESFLSASW--TPWFSPGAQQ 523
           9*****************************.....554....34689***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           D++E+l++lld+l+ee k   +   ++++++++ + ++e  ++++ ++ +++ ++++F+g++ ++i+cl+c nvs+ree f+dlsl++p
   Q: 524  DCSEYLKYLLDRLHEEEKT-GKRICQKLKQSNTPSPPEEqpSPNSSPNPSPTAVEKMFGGKIVTRIRCLRCLNVSTREEAFTDLSLAFP 611
           *****************44.444444444444444444434666677777799************************************ PP
   S: 178  gkeetkke................................................................................. 185
             + +  +                                                                                 
   Q: 612  PPDRRRRRvgsvmlpvedvrvqgppspaktpapgtegarrqrkhciagdalppvvsieilgfqepgghrekeeeiekkqeeekekmeer 700
           8887766699******************************************************************************* PP
   S: 186  ....................................................................slqdcLesftkeeelegenky 206
                                                                               s+ d+L+ f ++e+l+ en+y
   Q: 701  ekkeesedkkhqkekekkkeeeekevekkkekeekevekqkekekglraggnqgvafgeqmcgpegsrSVPDLLNYFLSPETLTAENRY 789
           ***************************************************************************************** PP
   S: 207  ycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls..pfctspeekqkekkkYeLiavvvHsG.slss 292
           +ce+c ++q+aek ++l++ P++Lil L Rfsf+ ++++r+ki ++v++pl L l     c ++e++q  +  Y+L++vvvHsG s++s
   Q: 790  HCEHCASLQDAEKVVELSEGPRYLILTLLRFSFDLRTMRRKKILDNVSIPLFLRLPmaGGCPQQEQGQ-ACAAYDLCSVVVHSGiSSES 877
           **************************************************775555216777766666.5******************* PP
   S: 293  GHYvayvkn......................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
           GHY++y+++                       + +W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 878  GHYYCYAREgataivnpsgpaglsaaekppgLESQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 949
           *********99999999999999888887777999*******************999************985 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MDKILEAVML STYPINVKQG LARRVIEAAK QPMDSAQCWA MLELSTKLFL VGDTKFKREI 60
GQEVLEVYGR YHLEAFVEFF NAHFLLTLLQ EGYGTPGHPS PYVLDYVQLG LQFIPEGPPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGATCTCTT GCTGCAGCCC AGGCGAGGAG CAGCTATGGA CAAGATCCTG GAAGCTGTGA 60
TGCTATCAAC CTATCCTATC AATGTGAAGC AAGGGCTGGC ACGGCGAGTG ATCGAGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	78.57	0.00e+00	835.00
IUUC-Apl-004121	Anas platyrhynchos	75.33	0.00e+00	1032.00
IUUC-Aca-005070	Anolis carolinensis	67.84	3.00e-172	598.00
IUUC-Bta-012545	Bos taurus	72.90	0.00e+00	957.00
IUUC-Cja-019731	Callithrix jacchus	73.68	0.00e+00	957.00
IUUC-Cfa-020095	Canis familiaris	74.78	0.00e+00	979.00
IUUC-Cpo-021961	Cavia porcellus	71.68	0.00e+00	946.00
IUUC-Csa-023167	Chlorocebus sabaeus	72.79	0.00e+00	934.00
IUUC-Cin-025604	Ciona intestinalis	28.07	7.00e-41	160.00
IUUC-Dno-029186	Dasypus novemcinctus	70.32	0.00e+00	697.00
IUUC-Dor-030538	Dipodomys ordii	75.70	0.00e+00	795.00
IUUC-Eca-033279	Equus caballus	80.12	0.00e+00	778.00
IUUC-Eeu-035120	Erinaceus europaeus	56.26	0.00e+00	669.00
IUUC-Fca-035969	Felis catus	79.72	0.00e+00	796.00
IUUC-Fal-037625	Ficedula albicollis	74.60	0.00e+00	1028.00
IUUC-Gga-040767	Gallus gallus	75.11	0.00e+00	1037.00
IUUC-Ggo-045323	Gorilla gorilla	77.65	0.00e+00	796.00
IUUC-Hsa-046124	Homo sapiens	73.01	0.00e+00	941.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	73.42	0.00e+00	949.00
IUUC-Lch-049513	Latimeria chalumnae	64.44	0.00e+00	835.00
IUUC-Loc-052698	Lepisosteus oculatus	58.67	0.00e+00	786.00
IUUC-Laf-053999	Loxodonta africana	71.16	0.00e+00	956.00
IUUC-Mcc-055266	Macaca mulatta	71.99	0.00e+00	917.00
IUUC-Meu-056906	Macropus eugenii	95.57	0.00e+00	1289.00
IUUC-Mga-059595	Meleagris gallopavo	72.86	0.00e+00	998.00
IUUC-Mdo-062167	Monodelphis domestica	94.68	0.00e+00	1290.00
IUUC-Mmu-063298	Mus musculus	74.17	0.00e+00	953.00
IUUC-Mpu-066195	Mustela putorius furo	73.78	0.00e+00	961.00
IUUC-Mlu-067583	Myotis lucifugus	79.11	0.00e+00	706.00
IUUC-Opr-070454	Ochotona princeps	64.57	6.00e-115	408.00
IUUC-Ocu-074121	Oryctolagus cuniculus	68.83	0.00e+00	801.00
IUUC-Oga-088593	Otolemur garnettii	72.98	0.00e+00	932.00
IUUC-Oar-090140	Ovis aries	72.46	0.00e+00	942.00
IUUC-Pan-092168	Papio anubis	72.94	0.00e+00	936.00
IUUC-Psi-093707	Pelodiscus sinensis	75.29	0.00e+00	1041.00
IUUC-Pab-097614	Pongo abelii	72.79	0.00e+00	944.00
IUUC-Pca-100683	Procavia capensis	69.56	0.00e+00	920.00
IUUC-Pva-103146	Pteropus vampyrus	64.60	0.00e+00	840.00
IUUC-Rno-105061	Rattus norvegicus	72.46	0.00e+00	953.00
IUUC-Tgu-117024	Taeniopygia guttata	75.11	0.00e+00	1034.00
IUUC-Tsy-119505	Tarsius syrichta	69.78	7.00e-150	524.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence