iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069183

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01095693

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000016630.2	ENSNLET00000021253.2	ENSNLEP00000020243.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-40	133.6	637	668
UBD/Beta-Prp	2.20e-62	210.9	57	372

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWD 29
           gHt+++t++a+   +d++lvs+s+Dgt +vWD
   Q: 637  GHTAKITSVAWsphHDGRLVSASYDGTAQVWD 668
           8***********8766**************** PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcl 129
           + +l gh++ v+  +fs++     + +t+s+D+t+k+wd++t + v     h++++ +l++sp  +d lvsG++  ++ ++  + +   
   Q: 57   IGELVGHTERVSGFTFSHHPGqynLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPrVKDLLVSGDEKGVVFCYWFNRNDSQ 145
           7899**************965677***************************************666**************855555555 PP
   S: 130  eetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls...........fdsng............. 192
              l ++ +++ c++ +p   +l++ G +D++v + d+ k g+++++l+g h+d ++s++           +                 
   Q: 146  --HLFIEPRTIFCLTCSPHHeDLVAIGYKDGIVVIIDIsKKGEVIHRLRG-HDDEIHSIAwcplpgedclsI---Nqeetseeaeitng 228
           ..4899999999999999999*****************999********9.*********777666666441...04667788888999 PP
   S: 193  ...........kelvsgsldgtvklwdlqtgec......................................vrtlnght.......... 222
                       +l++gs+d+t+++w++++g+                                       v      +          
   Q: 229  navaqapvtkgCYLATGSKDQTIRIWSCSRGRGvmilklpflkrrgagtdptvkerlwltlhwpsnqptqlV------Sscfggellqw 311
           99999999999******************8877445555555555555555555555555555555555552......05555557777 PP
   S: 223  ..........................dnvksvrfspnderlvsgssDgsiriWdlrsgdll 257
                                      n + +++ +++++l+s+s+D+ +++Wd+ + ++ 
   Q: 312  dltqswrrkytlfsassegqnhsrivFNLCPLQTEDDKQLLLSTSMDRDVKCWDMATLECC 372
           77777777777777777777777888788889999*******************9998885 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MGQEPRTLPP SPNWYCARCS DAVPGGLFGF AARTSVFLVR VGPGAGESPG TPPFRVIGEL 60
VGHTERVSGF TFSHHPGQYN LCATSSDDGT VKIWDVETKT VVTEHALHQH TISTLHWSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAGTTCAC CCCGCCCCGC TCCCTACCTA AAGCGTGAGG CTGCGAGCGG TCGGCTGTGG 60
CAGCTTCTCT TGGCTGTGGC AGCTTCTCTT GGCTCTGACG GCTTGTAGTT ATGGGGCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	88.10	0.00e+00	2574.00
IUUC-Apl-003586	Anas platyrhynchos	61.43	0.00e+00	1559.00
IUUC-Aca-004956	Anolis carolinensis	61.92	0.00e+00	1798.00
IUUC-Ame-010753	Astyanax mexicanus	62.24	0.00e+00	997.00
IUUC-Bta-012315	Bos taurus	87.05	0.00e+00	2573.00
IUUC-Cja-019334	Callithrix jacchus	94.77	0.00e+00	2850.00
IUUC-Cfa-021254	Canis familiaris	87.81	0.00e+00	2640.00
IUUC-Cpo-021984	Cavia porcellus	81.27	0.00e+00	2299.00
IUUC-Csa-023650	Chlorocebus sabaeus	96.36	0.00e+00	2847.00
IUUC-Cho-024860	Choloepus hoffmanni	82.36	0.00e+00	2344.00
IUUC-Cin-025778	Ciona intestinalis	37.23	0.00e+00	659.00
IUUC-Csv-026313	Ciona savignyi	40.45	5.00e-163	568.00
IUUC-Dre-028096	Danio rerio	63.17	0.00e+00	1007.00
IUUC-Dno-029799	Dasypus novemcinctus	89.08	0.00e+00	2230.00
IUUC-Dor-030885	Dipodomys ordii	73.85	0.00e+00	1078.00
IUUC-Ete-032918	Echinops telfairi	80.52	0.00e+00	2363.00
IUUC-Eca-034144	Equus caballus	87.64	0.00e+00	2521.00
IUUC-Eeu-034843	Erinaceus europaeus	78.14	0.00e+00	1736.00
IUUC-Fca-035948	Felis catus	87.91	0.00e+00	2580.00
IUUC-Fal-037303	Ficedula albicollis	61.22	0.00e+00	1732.00
IUUC-Gmo-039591	Gadus morhua	53.02	0.00e+00	841.00
IUUC-Gga-040570	Gallus gallus	61.82	0.00e+00	1582.00
IUUC-Gac-042646	Gasterosteus aculeatus	48.18	0.00e+00	1344.00
IUUC-Ggo-045605	Gorilla gorilla	87.74	0.00e+00	1974.00
IUUC-Hsa-046122	Homo sapiens	98.01	0.00e+00	2868.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	91.48	0.00e+00	2315.00
IUUC-Lch-050489	Latimeria chalumnae	57.10	0.00e+00	640.00
IUUC-Loc-052259	Lepisosteus oculatus	60.52	0.00e+00	973.00
IUUC-Laf-053338	Loxodonta africana	87.36	0.00e+00	2562.00
IUUC-Mcc-055442	Macaca mulatta	96.56	0.00e+00	2850.00
IUUC-Meu-056245	Macropus eugenii	80.90	0.00e+00	848.00
IUUC-Mga-060202	Meleagris gallopavo	62.06	0.00e+00	1644.00
IUUC-Mmr-061730	Microcebus murinus	89.27	0.00e+00	2600.00
IUUC-Mdo-062880	Monodelphis domestica	73.88	0.00e+00	2149.00
IUUC-Mmu-063930	Mus musculus	81.94	0.00e+00	2274.00
IUUC-Mpu-066605	Mustela putorius furo	87.76	0.00e+00	2601.00
IUUC-Mlu-067765	Myotis lucifugus	88.25	0.00e+00	2625.00
IUUC-Opr-070659	Ochotona princeps	77.53	0.00e+00	1142.00
IUUC-Ont-072356	Oreochromis niloticus	61.79	0.00e+00	1007.00
IUUC-Oan-073056	Ornithorhynchus anatinus	70.38	0.00e+00	1943.00
IUUC-Ocu-073881	Oryctolagus cuniculus	88.12	0.00e+00	2608.00
IUUC-Ola-087120	Oryzias latipes	57.49	3.00e-67	247.00
IUUC-Olu-087648	Ostreococcus lucimarinus	24.95	3.00e-31	130.00
IUUC-Oga-088343	Otolemur garnettii	90.07	0.00e+00	2643.00
IUUC-Oar-089257	Ovis aries	87.43	0.00e+00	2595.00
IUUC-Ptr-090497	Pan troglodytes	97.74	0.00e+00	2831.00
IUUC-Pan-092638	Papio anubis	96.17	0.00e+00	2835.00
IUUC-Psi-093096	Pelodiscus sinensis	64.42	0.00e+00	1574.00
IUUC-Pma-094571	Petromyzon marinus	43.55	6.00e-87	314.00
IUUC-Pfo-096742	Poecilia formosa	48.81	0.00e+00	1344.00
IUUC-Pab-098153	Pongo abelii	97.28	0.00e+00	2871.00
IUUC-Pca-100957	Procavia capensis	80.52	0.00e+00	2358.00
IUUC-Pva-102439	Pteropus vampyrus	89.34	0.00e+00	2657.00
IUUC-Rno-105891	Rattus norvegicus	82.14	0.00e+00	2265.00
IUUC-Sha-107181	Sarcophilus harrisii	73.91	0.00e+00	2057.00
IUUC-Ssc-115413	Sus scrofa	87.65	0.00e+00	2617.00
IUUC-Tgu-117082	Taeniopygia guttata	61.92	0.00e+00	1721.00
IUUC-Tru-118491	Takifugu rubripes	58.96	0.00e+00	946.00
IUUC-Tsy-119629	Tarsius syrichta	93.43	9.00e-165	574.00
IUUC-Tni-120240	Tetraodon nigroviridis	59.59	0.00e+00	952.00
IUUC-Tbe-127673	Tupaia belangeri	77.87	0.00e+00	2133.00
IUUC-Ttr-128562	Tursiops truncatus	85.17	0.00e+00	2518.00
IUUC-Vpa-130596	Vicugna pacos	84.39	0.00e+00	1852.00
IUUC-Xtr-132469	Xenopus tropicalis	56.36	0.00e+00	1602.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence