iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062082

UUCD1 version

UUC-MoD-00487

Ensembl Protein ID

ENSMODP00000018408.2

UniProt Accession

F6ZD39; F6ZD39_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000014725.2	ENSMODT00000018741.2	ENSMODP00000018408.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.40e-16	58.1	98	172
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.20e-09	37.3	206	236

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvg...geeffahkivLaasSsvFyalflmeleesksklmveikd......vqpevfrallkFlYtgklde 67
           +D++l+ g   g+ef+ah++vLaa+ ++F  l++++++es+ +++ve++        +p+ ++a+++++Ytg+++ 
   Q: 98   CDITLCFGgagGREFRAHRSVLAAATEYFTPLLSGQFSESR-SGRVEMRKwssepgPEPDTVEAVIEYMYTGRIRV 172
           8******7788******************************.*******4456799*****************975 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           l+Nc++i ++A++y++++L+++a d+i ++F
   Q: 206  LSNCVAIHSLAHMYTLSQLALKAADMIRRNF 236
           69****************************9 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

RSLLRTRSNM AASAAASLQV VEMEGVEAAV SGPVGLGVEG MGISGSVAAE AGLGAGLASM 60
AEVVGREPGP ESEDFECSTH CSELSWRQNE QRRQGLFCDI TLCFGGAGGR EFRAHRSVLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAAGCCTGC TGCGTACCCG GAGCAATATG GCTGCGTCGG CGGCTGCATC CCTTCAGGTG 60
GTGGAGATGG AGGGGGTGGA AGCAGCCGTC TCCGGGCCCG TGGGGCTGGG AGTGGAAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002239	Ailuropoda melanoleuca	89.56	0.00e+00	1243.00
IUUC-Apl-003928	Anas platyrhynchos	88.53	0.00e+00	1091.00
IUUC-Aca-004801	Anolis carolinensis	83.98	0.00e+00	1132.00
IUUC-Ame-010943	Astyanax mexicanus	77.58	0.00e+00	933.00
IUUC-Bta-012341	Bos taurus	98.81	3.00e-96	343.00
IUUC-Cja-019924	Callithrix jacchus	88.49	0.00e+00	1281.00
IUUC-Cfa-021076	Canis familiaris	88.63	0.00e+00	1286.00
IUUC-Cpo-022193	Cavia porcellus	85.61	0.00e+00	1216.00
IUUC-Csa-023614	Chlorocebus sabaeus	90.15	0.00e+00	1276.00
IUUC-Cho-024806	Choloepus hoffmanni	77.08	0.00e+00	858.00
IUUC-Dre-028622	Danio rerio	76.41	0.00e+00	1019.00
IUUC-Dno-029965	Dasypus novemcinctus	86.70	0.00e+00	1245.00
IUUC-Dor-030136	Dipodomys ordii	91.06	0.00e+00	1023.00
IUUC-Eca-034191	Equus caballus	91.10	0.00e+00	1260.00
IUUC-Eeu-034746	Erinaceus europaeus	87.77	0.00e+00	1272.00
IUUC-Fca-035702	Felis catus	83.23	0.00e+00	1149.00
IUUC-Fal-037360	Ficedula albicollis	87.67	0.00e+00	1077.00
IUUC-Gmo-038582	Gadus morhua	76.13	0.00e+00	1032.00
IUUC-Ggr-039747	Gaeumannomyces graminis	23.83	7.00e-08	51.20
IUUC-Gga-040375	Gallus gallus	88.04	0.00e+00	1185.00
IUUC-Gac-042523	Gasterosteus aculeatus	78.08	0.00e+00	1019.00
IUUC-Ggo-045632	Gorilla gorilla	91.10	0.00e+00	1023.00
IUUC-Hsa-046817	Homo sapiens	88.63	0.00e+00	1285.00
IUUC-Itr-048433	Ictidomys tridecemlineatus	88.78	0.00e+00	1288.00
IUUC-Lch-049985	Latimeria chalumnae	79.65	0.00e+00	1046.00
IUUC-Loc-052594	Lepisosteus oculatus	77.25	0.00e+00	1013.00
IUUC-Lma-053111	Leptosphaeria maculans	31.65	9.00e-05	40.40
IUUC-Laf-054357	Loxodonta africana	88.63	0.00e+00	1288.00
IUUC-Mcc-055454	Macaca mulatta	91.86	0.00e+00	1268.00
IUUC-Meu-056012	Macropus eugenii	94.65	0.00e+00	649.00
IUUC-Mga-060048	Meleagris gallopavo	90.02	0.00e+00	914.00
IUUC-Mmu-063119	Mus musculus	88.20	0.00e+00	1302.00
IUUC-Mpu-066511	Mustela putorius furo	88.49	0.00e+00	1286.00
IUUC-Mlu-067301	Myotis lucifugus	87.77	0.00e+00	1255.00
IUUC-Nfi-068503	Neosartorya fischeri	33.33	7.00e-03	34.30
IUUC-Nle-069912	Nomascus leucogenys	88.63	0.00e+00	1285.00
IUUC-Opr-070762	Ochotona princeps	88.15	0.00e+00	772.00
IUUC-Ont-071916	Oreochromis niloticus	78.76	0.00e+00	1016.00
IUUC-Oan-072932	Ornithorhynchus anatinus	79.70	0.00e+00	849.00
IUUC-Ocu-074172	Oryctolagus cuniculus	90.77	0.00e+00	1008.00
IUUC-Ola-086483	Oryzias latipes	78.45	0.00e+00	1014.00
IUUC-Oga-088112	Otolemur garnettii	88.86	0.00e+00	1234.00
IUUC-Oar-090129	Ovis aries	88.63	0.00e+00	1285.00
IUUC-Ptr-090571	Pan troglodytes	91.06	0.00e+00	1020.00
IUUC-Pan-092073	Papio anubis	88.63	0.00e+00	1285.00
IUUC-Psi-093836	Pelodiscus sinensis	89.47	0.00e+00	1127.00
IUUC-Pno-095007	Phaeosphaeria nodorum	31.08	6.00e-05	41.60
IUUC-Pfo-096477	Poecilia formosa	78.60	0.00e+00	1016.00
IUUC-Pab-098473	Pongo abelii	88.63	0.00e+00	1285.00
IUUC-Pca-100239	Procavia capensis	87.33	0.00e+00	761.00
IUUC-Pte-104232	Pyrenophora teres	35.62	7.00e-05	41.20
IUUC-Pyt-104638	Pyrenophora triticirepentis	38.10	5.00e-05	41.60
IUUC-Rno-104859	Rattus norvegicus	88.20	0.00e+00	1303.00
IUUC-Sha-106746	Sarcophilus harrisii	96.07	0.00e+00	1375.00
IUUC-Tgu-117183	Taeniopygia guttata	87.35	0.00e+00	1184.00
IUUC-Tru-118655	Takifugu rubripes	74.93	0.00e+00	1014.00
IUUC-Tsy-119430	Tarsius syrichta	92.63	0.00e+00	1255.00
IUUC-Tni-119698	Tetraodon nigroviridis	78.21	0.00e+00	897.00
IUUC-Vda-129848	Verticillium dahliae	33.33	1.00e-03	37.40
IUUC-Vpa-130715	Vicugna pacos	87.88	0.00e+00	1273.00
IUUC-Xtr-132276	Xenopus tropicalis	78.19	0.00e+00	1010.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence